(21 nodes) Terpenoid backbone biosynthesis network (Taeniopygia guttata)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	PCYOX1L	Prenylcysteine oxidase 1 like. (403 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (368 aa)
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (333 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (382 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (777 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1030 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	LOC100223864	Uncharacterized protein. (409 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (507 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (282 aa)
	PDSS2	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (389 aa)
	FDPS	Farnesyl diphosphate synthase. (345 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (507 aa)
	IDI1	Nudix hydrolase domain-containing protein. (266 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (469 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (434 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (466 aa)
	LOC100222230	Prenylcysteine oxidase / farnesylcysteine lyase. (496 aa)
	LOC115492109	Prenyl protein peptidase. (314 aa)
	PMVK	Phosphomevalonate kinase. (205 aa)
	ACAT1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (423 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	ACAT2	ENSTGUP00000037793	ENSTGUP00000011754	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.915
ACAT1	HMGCR	ENSTGUP00000037793	ENSTGUP00000006291	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.461
ACAT1	HMGCS1	ENSTGUP00000037793	ENSTGUP00000002355	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
ACAT1	HMGCS2	ENSTGUP00000037793	ENSTGUP00000017522	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
ACAT1	IDI1	ENSTGUP00000037793	ENSTGUP00000020955	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Nudix hydrolase domain-containing protein.	0.437
ACAT1	MVK	ENSTGUP00000037793	ENSTGUP00000007608	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.680
ACAT2	ACAT1	ENSTGUP00000011754	ENSTGUP00000037793	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.915
ACAT2	FDPS	ENSTGUP00000011754	ENSTGUP00000016832	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Farnesyl diphosphate synthase.	0.449
ACAT2	HMGCR	ENSTGUP00000011754	ENSTGUP00000006291	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.546
ACAT2	HMGCS1	ENSTGUP00000011754	ENSTGUP00000002355	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.990
ACAT2	HMGCS2	ENSTGUP00000011754	ENSTGUP00000017522	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.987
ACAT2	IDI1	ENSTGUP00000011754	ENSTGUP00000020955	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Nudix hydrolase domain-containing protein.	0.553
ACAT2	MVK	ENSTGUP00000011754	ENSTGUP00000007608	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.683
DHDDS	FDPS	ENSTGUP00000001059	ENSTGUP00000016832	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyl diphosphate synthase.	0.957
DHDDS	FNTA	ENSTGUP00000001059	ENSTGUP00000000282	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyltransferase, CAAX box, alpha.	0.957
DHDDS	GGPS1	ENSTGUP00000001059	ENSTGUP00000025781	Alkyl transferase; Belongs to the UPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.960
DHDDS	HMGCR	ENSTGUP00000001059	ENSTGUP00000006291	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.540
DHDDS	IDI1	ENSTGUP00000001059	ENSTGUP00000020955	Alkyl transferase; Belongs to the UPP synthase family.	Nudix hydrolase domain-containing protein.	0.894
DHDDS	LOC100223864	ENSTGUP00000001059	ENSTGUP00000007714	Alkyl transferase; Belongs to the UPP synthase family.	Uncharacterized protein.	0.941
DHDDS	MVK	ENSTGUP00000001059	ENSTGUP00000007608	Alkyl transferase; Belongs to the UPP synthase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.537