STRINGSTRING
PPP2CA PPP2CA PPP2CB PPP2CB MTOR MTOR IGBP1 IGBP1 BECN1 BECN1 PIK3R4 PIK3R4 ATG4A ATG4A ATG9A ATG9A ATG4B ATG4B ATG10 ATG10 ULK2 ULK2 ATG16L1 ATG16L1 ATG4C ATG4C ATG2B ATG2B ATG101 ATG101 ATG12 ATG12 MLST8 MLST8 GABARAPL2 GABARAPL2 ATG4D ATG4D ATG5 ATG5 ATG7 ATG7 GABARAPL1 GABARAPL1 WIPI2 WIPI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (1322 aa)
IGBP1Uncharacterized protein. (341 aa)
BECN1Uncharacterized protein. (449 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1361 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (397 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (869 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (377 aa)
ATG10Autophagy related 10. (226 aa)
ULK2Protein kinase domain-containing protein. (1076 aa)
ATG16L1Autophagy related 16 like 1. (608 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (456 aa)
ATG2BUncharacterized protein. (2078 aa)
ATG101Uncharacterized protein. (310 aa)
ATG12Autophagy related 12. (249 aa)
MLST8MTOR associated protein, LST8 homolog. (325 aa)
GABARAPL2Uncharacterized protein. (120 aa)
ATG4DCysteine protease ATG4D isoform X1. (590 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (796 aa)
GABARAPL1GABA type A receptor associated protein like 1. (132 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (456 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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