56 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UQCRQ	Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
	TPM4	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (803 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (933 aa)
	CACNA2D1	VWFA domain-containing protein. (1085 aa)
	SLC9A6	Solute carrier family 9 member A6. (681 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (323 aa)
	LOC100221209	Uncharacterized protein. (145 aa)
	ATP2A3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (952 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
	CACNG1	Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (226 aa)
	CACNA2D2	VGCC_alpha2 domain-containing protein. (1113 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1043 aa)
	COX7B	Putative cytochrome c oxidase subunit VIIb variant 1. (78 aa)
	MYL2	Myosin light chain 2. (165 aa)
	COX7C	Putative cytochrome c oxidase subunit VIIc. (75 aa)
	CACNA2D3	Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1103 aa)
	UQCRH	Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (146 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (289 aa)
	UQCRFS1	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (273 aa)
	UQCR10	Uncharacterized protein. (59 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
	ACTC1	Actin alpha cardiac muscle 1. (377 aa)
	UQCRB	Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
	COX6C	Putative cytochrome c oxidase subunit VIc. (107 aa)
	COX7A2	Putative cytochrome c oxidase subunit VIIa 2. (83 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (407 aa)
	COX5B	Cytochrome c oxidase subunit 5B, mitochondrial. (126 aa)
	CACNA2D4	VWFA domain-containing protein. (1098 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2148 aa)
	CACNG3	Calcium voltage-gated channel auxiliary subunit gamma 3. (401 aa)
	UQCRC1	Ubiquinol-cytochrome c reductase core protein 1. (486 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1327 aa)
	FXYD2	Sodium/potassium-transporting ATPase subunit gamma. (78 aa)
	ENSTGUP00000024467	Myosin heavy chain 6/7. (1925 aa)
	CACNG5	Calcium voltage-gated channel auxiliary subunit gamma 5. (279 aa)
	TPM1	Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
	RYR2	Ryanodine receptor 2. (4939 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha-2. (1020 aa)
	TPM3	Tropomyosin 3; Belongs to the tropomyosin family. (294 aa)
	ATP2A1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1. (1187 aa)
	SLC8A3	Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
	UQCRC2	Ubiquinol-cytochrome c reductase core protein 2. (457 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1849 aa)
	CACNB2	Calcium voltage-gated channel auxiliary subunit beta 2. (651 aa)
	TNNC1	Troponin C1, slow skeletal and cardiac type. (176 aa)
	COX7A2L	Cytochrome c oxidase subunit 7A2 like. (116 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2179 aa)
	MYH7	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (295 aa)
	CACNB4	SH3 domain-containing protein. (478 aa)
	LOC100222254	Cytochrome c oxidase subunit 4I1. (464 aa)
	SLC9A7	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (709 aa)
	MYL4	Uncharacterized protein. (203 aa)
	LOC115492946	Cytochrome c oxidase subunit 6B1. (111 aa)
	CACNB1	Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (501 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTC1	ENSTGUP00000024467	ENSTGUP00000012148	ENSTGUP00000024467	Actin alpha cardiac muscle 1.	Myosin heavy chain 6/7.	0.936
ACTC1	MYH7	ENSTGUP00000012148	ENSTGUP00000034137	Actin alpha cardiac muscle 1.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.936
ACTC1	MYL2	ENSTGUP00000012148	ENSTGUP00000006639	Actin alpha cardiac muscle 1.	Myosin light chain 2.	0.934
ACTC1	MYL4	ENSTGUP00000012148	ENSTGUP00000038051	Actin alpha cardiac muscle 1.	Uncharacterized protein.	0.931
ACTC1	TPM1	ENSTGUP00000012148	ENSTGUP00000025553	Actin alpha cardiac muscle 1.	Uncharacterized protein; Belongs to the tropomyosin family.	0.951
ACTC1	TPM3	ENSTGUP00000012148	ENSTGUP00000028562	Actin alpha cardiac muscle 1.	Tropomyosin 3; Belongs to the tropomyosin family.	0.951
ACTC1	TPM4	ENSTGUP00000012148	ENSTGUP00000000739	Actin alpha cardiac muscle 1.	Uncharacterized protein; Belongs to the tropomyosin family.	0.951
ATP1A1	ATP1A2	ENSTGUP00000023777	ENSTGUP00000028350	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha-2.	0.900
ATP1A1	ATP1B1	ENSTGUP00000023777	ENSTGUP00000035523	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
ATP1A1	ATP1B3	ENSTGUP00000023777	ENSTGUP00000008695	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.960
ATP1A1	ATP1B4	ENSTGUP00000023777	ENSTGUP00000003580	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.959
ATP1A1	FXYD2	ENSTGUP00000023777	ENSTGUP00000023879	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit gamma.	0.979
ATP1A2	ATP1A1	ENSTGUP00000028350	ENSTGUP00000023777	Sodium/potassium-transporting ATPase subunit alpha-2.	Sodium/potassium-transporting ATPase subunit alpha.	0.900
ATP1A2	ATP1B1	ENSTGUP00000028350	ENSTGUP00000035523	Sodium/potassium-transporting ATPase subunit alpha-2.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.982
ATP1A2	ATP1B3	ENSTGUP00000028350	ENSTGUP00000008695	Sodium/potassium-transporting ATPase subunit alpha-2.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.960
ATP1A2	ATP1B4	ENSTGUP00000028350	ENSTGUP00000003580	Sodium/potassium-transporting ATPase subunit alpha-2.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.959
ATP1A2	FXYD2	ENSTGUP00000028350	ENSTGUP00000023879	Sodium/potassium-transporting ATPase subunit alpha-2.	Sodium/potassium-transporting ATPase subunit gamma.	0.979
ATP1B1	ATP1A1	ENSTGUP00000035523	ENSTGUP00000023777	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit alpha.	0.982
ATP1B1	ATP1A2	ENSTGUP00000035523	ENSTGUP00000028350	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit alpha-2.	0.982
ATP1B1	ATP1B3	ENSTGUP00000035523	ENSTGUP00000008695	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.940