STRINGSTRING
SMAD2 SMAD2 SMAD7 SMAD7 ACVR2B ACVR2B ID3 ID3 BAMBI BAMBI RGMB RGMB SMAD5 SMAD5 PPP2CA PPP2CA SKP1 SKP1 LOC100218902 LOC100218902 PPP2CB PPP2CB CUL1 CUL1 INHBA INHBA FST FST SMAD1 SMAD1 RBL1 RBL1 TGFBR2 TGFBR2 GDF5 GDF5 LOC100224677 LOC100224677 CREBBP CREBBP LOC100232580 LOC100232580 PITX2 PITX2 E2F4 E2F4 BMPR1A BMPR1A RPS6KB2 RPS6KB2 ID4 ID4 RHOA RHOA TGFBR1 TGFBR1 SMURF1 SMURF1 RPS6KB1 RPS6KB1 ZFYVE9 ZFYVE9 TFDP1 TFDP1 SMAD6 SMAD6 EP300 EP300 RBX1 RBX1 BMPR2 BMPR2 ROCK1 ROCK1 THBS1 THBS1 E2F5 E2F5 SMAD9 SMAD9 ACVR2A ACVR2A MYC MYC BMP5 BMP5 ID2 ID2 HJV HJV INHBC INHBC PPP2R1A PPP2R1A FMOD FMOD ZFYVE16 ZFYVE16 LOC100217480 LOC100217480 LOC115491349 LOC115491349 GREM1 GREM1 BMP6 BMP6 LOC115496678 LOC115496678 SMURF2 SMURF2 BMP4 BMP4 BMP2 BMP2 H0Z191_TAEGU H0Z191_TAEGU ACVR1B ACVR1B GDF6 GDF6 TGIF1 TGIF1 THSD4 THSD4 TGFB3 TGFB3 TGIF2 TGIF2 ID1 ID1 MAPK1 MAPK1 BMP7 BMP7 LTBP1 LTBP1 GDF7 GDF7 AMHR2 AMHR2 NBL1 NBL1 IFNG IFNG RGMA RGMA BMPR1B BMPR1B ENSTGUP00000035464 ENSTGUP00000035464 INHBB INHBB GREM2 GREM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD2Mothers against decapentaplegic homolog. (487 aa)
SMAD7MH1 domain-containing protein. (392 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (125 aa)
BAMBIBMP and activin membrane bound inhibitor. (261 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (406 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC100218902ANK_REP_REGION domain-containing protein. (294 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
INHBAInhibin subunit beta A. (559 aa)
FSTFollistatin. (343 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
RBL1RB transcriptional corepressor like 1. (977 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
GDF5Growth differentiation factor 5. (500 aa)
LOC100224677TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
CREBBPCREB binding protein. (1929 aa)
LOC100232580TGF_BETA_2 domain-containing protein. (364 aa)
PITX2Homeobox protein. (360 aa)
E2F4E2F transcription factor 4. (402 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
RPS6KB2Ribosomal protein S6 kinase beta-2 isoform X1. (671 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (139 aa)
RHOAUncharacterized protein. (193 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (501 aa)
SMURF1E3 ubiquitin-protein ligase. (737 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1410 aa)
TFDP1Transcription factor. (412 aa)
SMAD6SMAD family member 6. (477 aa)
EP300E1A binding protein p300. (2445 aa)
RBX1Ring-box 1. (108 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
ROCK1Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1358 aa)
THBS1Uncharacterized protein. (1173 aa)
E2F5E2F transcription factor 5. (372 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (418 aa)
BMP5Bone morphogenetic protein 5. (453 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
HJVHemojuvelin BMP co-receptor. (575 aa)
INHBCInhibin subunit beta C. (449 aa)
PPP2R1AUncharacterized protein. (587 aa)
FMODFibromodulin. (382 aa)
ZFYVE16FYVE-type domain-containing protein. (1520 aa)
LOC100217480TGF_BETA_2 domain-containing protein. (376 aa)
LOC115491349Transcription factor Sp1. (764 aa)
GREM1Gremlin. (184 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
LOC115496678Neogenin 1. (1433 aa)
SMURF2E3 ubiquitin-protein ligase. (777 aa)
BMP4Bone morphogenetic protein 4. (420 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
H0Z191_TAEGUMothers against decapentaplegic homolog. (343 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (516 aa)
GDF6Growth differentiation factor 6. (318 aa)
TGIF1TGFB induced factor homeobox 1. (269 aa)
THSD4Thrombospondin type 1 domain containing 4. (1033 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (533 aa)
TGIF2Uncharacterized protein. (245 aa)
ID1DNA-binding protein inhibitor ID-1. (162 aa)
MAPK1Mitogen-activated protein kinase. (369 aa)
BMP7Bone morphogenetic protein 7. (459 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1709 aa)
GDF7Growth differentiation factor 7. (369 aa)
AMHR2LOW QUALITY PROTEIN: anti-Muellerian hormone type-2 receptor. (574 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (196 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (445 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ENSTGUP00000035464Inhibin beta C chain. (514 aa)
INHBBInhibin beta B chain. (392 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (341 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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