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IL12B IL12B IFNAR1 IFNAR1 MAP2K2 MAP2K2 MAP3K8 MAP3K8 LOC100223328 LOC100223328 LOC100222345 LOC100222345 MAPK13 MAPK13 TLR5 TLR5 PIK3R1 PIK3R1 TLR4 TLR4 MAPK12 MAPK12 MAPK11 MAPK11 LOC100228379 LOC100228379 CHUK CHUK IKBKB IKBKB CD40 CD40 MAP2K4 MAP2K4 TBK1 TBK1 TLR3 TLR3 MAP2K3 MAP2K3 LOC100221185 LOC100221185 MAP2K1 MAP2K1 JUN JUN TAB1 TAB1 LOC100223333 LOC100223333 TAB2 TAB2 PIK3CA PIK3CA STAT1 STAT1 LY96 LY96 NFKBIA NFKBIA CD86 CD86 CD80 CD80 MAPK10 MAPK10 PIK3CD PIK3CD PIK3R2 PIK3R2 TIRAP TIRAP AKT3 AKT3 PIK3CB PIK3CB RELA RELA IRF5 IRF5 IKBKE IKBKE MAP3K7 MAP3K7 TOLLIP TOLLIP TRAF6 TRAF6 TRAF3 TRAF3 LOC115497673 LOC115497673 IRAK4 IRAK4 RAC1 RAC1 LOC100232395 LOC100232395 FOS FOS CTSK CTSK LOC105760863 LOC105760863 ENSTGUP00000030391 ENSTGUP00000030391 CASP8 CASP8 NFKB1 NFKB1 MAPK1 MAPK1 AKT1 AKT1 TLR7 TLR7 RIPK1 RIPK1 MAP2K6 MAP2K6 FADD FADD LOC100226645 LOC100226645 MAPK14 MAPK14 MAPK9 MAPK9 CCL17 CCL17 C28H19orf25 C28H19orf25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (312 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (604 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (698 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)
LOC100223328Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
LOC100222345Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
MAPK13Mitogen-activated protein kinase. (361 aa)
TLR5TIR domain-containing protein; Belongs to the Toll-like receptor family. (859 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (842 aa)
MAPK12Mitogen-activated protein kinase. (361 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
LOC100228379Uncharacterized protein. (184 aa)
CHUKProtein kinase domain-containing protein. (762 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
CD40CD40 molecule. (280 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (483 aa)
TBK1TANK binding kinase 1. (729 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa)
LOC100221185Uncharacterized protein. (738 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (399 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
LOC100223333Caspase 8. (459 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT1Signal transducer and activator of transcription. (755 aa)
LY96Lymphocyte antigen 96. (154 aa)
NFKBIAANK_REP_REGION domain-containing protein. (331 aa)
CD86CD86 molecule. (302 aa)
CD80Uncharacterized protein. (361 aa)
MAPK10Mitogen-activated protein kinase. (472 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
PIK3R2Uncharacterized protein. (727 aa)
TIRAPTIR domain containing adaptor protein. (410 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (533 aa)
PIK3CBUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
RELATranscription factor p65 isoform X1. (371 aa)
IRF5IRF-3 domain-containing protein. (488 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (757 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (627 aa)
TOLLIPToll interacting protein. (280 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (544 aa)
LOC115497673Fibronectin type-III domain-containing protein. (501 aa)
IRAK4Protein kinase domain-containing protein. (527 aa)
RAC1Rac family small GTPase 1. (255 aa)
LOC100232395TIR domain-containing protein; Belongs to the Toll-like receptor family. (653 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (331 aa)
LOC105760863Uncharacterized protein. (190 aa)
ENSTGUP00000030391Interleukin-8-like. (96 aa)
CASP8Caspase 8. (480 aa)
NFKB1Nuclear factor kappa B subunit 1. (982 aa)
MAPK1Mitogen-activated protein kinase. (369 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
MAP2K6Protein kinase domain-containing protein. (334 aa)
FADDFas associated via death domain. (221 aa)
LOC100226645TIR domain-containing protein; Belongs to the Toll-like receptor family. (796 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CCL17C-C motif chemokine. (102 aa)
C28H19orf25Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein. (168 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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