(20 nodes) Autophagy - other network (Agaricus bisporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	K5W1I9_AGABU	Uncharacterized protein. (455 aa)
	K5WJE6_AGABU	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (1191 aa)
	K5WS97_AGABU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
	K5WVV9_AGABU	Uncharacterized protein. (279 aa)
	K5X0D6_AGABU	Uncharacterized protein. (455 aa)
	K5X2V0_AGABU	Uncharacterized protein. (1355 aa)
	K5X614_AGABU	Uncharacterized protein. (1658 aa)
	K5X6S8_AGABU	Phosphatidylinositol 3-kinase VPS34. (848 aa)
	K5XC29_AGABU	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (354 aa)
	K5XF85_AGABU	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (113 aa)
	K5XI43_AGABU	Autophagy-related protein. (127 aa)
	K5XIH5_AGABU	Uncharacterized protein. (186 aa)
	K5XJL3_AGABU	ATG16 domain-containing protein. (268 aa)
	K5XJY1_AGABU	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (657 aa)
	K5XMT6_AGABU	Autophagy-related protein 3. (390 aa)
	K5XR24_AGABU	ATG11 domain-containing protein. (1328 aa)
	K5XTD1_AGABU	DUF3543 domain-containing protein. (387 aa)
	K5Y3R1_AGABU	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (584 aa)
	K5Y3T2_AGABU	Uncharacterized protein. (1955 aa)
	K5Y692_AGABU	Uncharacterized protein. (919 aa)

Your Current Organism:

Agaricus bisporus

NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K5W1I9_AGABU	K5WJE6_AGABU	K5W1I9	K5WJE6	Uncharacterized protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.570
K5W1I9_AGABU	K5WS97_AGABU	K5W1I9	K5WS97	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
K5W1I9_AGABU	K5WVV9_AGABU	K5W1I9	K5WVV9	Uncharacterized protein.	Uncharacterized protein.	0.809
K5W1I9_AGABU	K5X0D6_AGABU	K5W1I9	K5X0D6	Uncharacterized protein.	Uncharacterized protein.	0.904
K5W1I9_AGABU	K5X2V0_AGABU	K5W1I9	K5X2V0	Uncharacterized protein.	Uncharacterized protein.	0.674
K5W1I9_AGABU	K5X614_AGABU	K5W1I9	K5X614	Uncharacterized protein.	Uncharacterized protein.	0.999
K5W1I9_AGABU	K5X6S8_AGABU	K5W1I9	K5X6S8	Uncharacterized protein.	Phosphatidylinositol 3-kinase VPS34.	0.999
K5W1I9_AGABU	K5XC29_AGABU	K5W1I9	K5XC29	Uncharacterized protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.873
K5W1I9_AGABU	K5XF85_AGABU	K5W1I9	K5XF85	Uncharacterized protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.908
K5W1I9_AGABU	K5XI43_AGABU	K5W1I9	K5XI43	Uncharacterized protein.	Autophagy-related protein.	0.890
K5W1I9_AGABU	K5XIH5_AGABU	K5W1I9	K5XIH5	Uncharacterized protein.	Uncharacterized protein.	0.892
K5W1I9_AGABU	K5XJL3_AGABU	K5W1I9	K5XJL3	Uncharacterized protein.	ATG16 domain-containing protein.	0.897
K5W1I9_AGABU	K5XJY1_AGABU	K5W1I9	K5XJY1	Uncharacterized protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.675
K5W1I9_AGABU	K5XMT6_AGABU	K5W1I9	K5XMT6	Uncharacterized protein.	Autophagy-related protein 3.	0.809
K5W1I9_AGABU	K5XR24_AGABU	K5W1I9	K5XR24	Uncharacterized protein.	ATG11 domain-containing protein.	0.678
K5W1I9_AGABU	K5XTD1_AGABU	K5W1I9	K5XTD1	Uncharacterized protein.	DUF3543 domain-containing protein.	0.947
K5W1I9_AGABU	K5Y3R1_AGABU	K5W1I9	K5Y3R1	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.884
K5W1I9_AGABU	K5Y3T2_AGABU	K5W1I9	K5Y3T2	Uncharacterized protein.	Uncharacterized protein.	0.630
K5W1I9_AGABU	K5Y692_AGABU	K5W1I9	K5Y692	Uncharacterized protein.	Uncharacterized protein.	0.996
K5WJE6_AGABU	K5W1I9_AGABU	K5WJE6	K5W1I9	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	Uncharacterized protein.	0.570