(39 nodes) Toll Like Receptor TLR6:TLR2 Cascade network (Agaricus bisporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	K5XJP0_AGABU	Uncharacterized protein. (336 aa)
	K5XJ54_AGABU	Uncharacterized protein. (301 aa)
	K5XHT9_AGABU	Uncharacterized protein. (307 aa)
	K5XGB0_AGABU	Uncharacterized protein. (294 aa)
	K5XEW1_AGABU	Ubiquitin-like domain-containing protein. (159 aa)
	K5XBK0_AGABU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	K5X7H8_AGABU	Uncharacterized protein. (593 aa)
	K5X7A1_AGABU	Uncharacterized protein. (164 aa)
	K5X766_AGABU	Uncharacterized protein. (114 aa)
	K5X2E2_AGABU	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (384 aa)
	K5X265_AGABU	Uncharacterized protein. (465 aa)
	K5X1I2_AGABU	Uncharacterized protein. (191 aa)
	K5X1F5_AGABU	Uncharacterized protein. (519 aa)
	K5X0S1_AGABU	APH domain-containing protein. (152 aa)
	K5WWJ8_AGABU	HEME_HALOPEROXIDASE domain-containing protein. (462 aa)
	K5WVM8_AGABU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	K5WV85_AGABU	Uncharacterized protein. (297 aa)
	K5WJK7_AGABU	Uncharacterized protein. (181 aa)
	K5W7E6_AGABU	Uncharacterized protein. (1104 aa)
	K5W4V4_AGABU	Mitogen-activated protein kinase. (711 aa)
	K5XJP2_AGABU	Uncharacterized protein. (305 aa)
	K5XK44_AGABU	Uncharacterized protein. (313 aa)
	K5XKV0_AGABU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (495 aa)
	K5XQY7_AGABU	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
	K5XZ40_AGABU	RING-type domain-containing protein. (452 aa)
	K5XZX5_AGABU	Uncharacterized protein. (127 aa)
	K5Y1W4_AGABU	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (166 aa)
	K5Y7K5_AGABU	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (344 aa)
	K5W1W1_AGABU	Uncharacterized protein. (197 aa)
	K5W1R2_AGABU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
	K5W1P9_AGABU	Protein kinase domain-containing protein. (328 aa)
	K5W0C4_AGABU	BZIP domain-containing protein. (373 aa)
	K5VZQ9_AGABU	Uncharacterized protein. (414 aa)
	K5VZE1_AGABU	Uncharacterized protein. (280 aa)
	K5VWK2_AGABU	Serine/threonine-protein phosphatase. (304 aa)
	K5VWC0_AGABU	Metallophos domain-containing protein. (471 aa)
	K5VV89_AGABU	APH domain-containing protein. (189 aa)
	K5VNW5_AGABU	Uncharacterized protein. (185 aa)
	K5VJF5_AGABU	Uncharacterized protein. (256 aa)

Your Current Organism:

Agaricus bisporus

NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K5VNW5_AGABU	K5W1R2_AGABU	K5VNW5	K5W1R2	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.434
K5VNW5_AGABU	K5W4V4_AGABU	K5VNW5	K5W4V4	Uncharacterized protein.	Mitogen-activated protein kinase.	0.434
K5VNW5_AGABU	K5X265_AGABU	K5VNW5	K5X265	Uncharacterized protein.	Uncharacterized protein.	0.434
K5VNW5_AGABU	K5X2E2_AGABU	K5VNW5	K5X2E2	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.434
K5VNW5_AGABU	K5XQY7_AGABU	K5VNW5	K5XQY7	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.434
K5VNW5_AGABU	K5Y7K5_AGABU	K5VNW5	K5Y7K5	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.434
K5VWC0_AGABU	K5W7E6_AGABU	K5VWC0	K5W7E6	Metallophos domain-containing protein.	Uncharacterized protein.	0.807
K5VWC0_AGABU	K5X7H8_AGABU	K5VWC0	K5X7H8	Metallophos domain-containing protein.	Uncharacterized protein.	0.807
K5VWC0_AGABU	K5XEW1_AGABU	K5VWC0	K5XEW1	Metallophos domain-containing protein.	Ubiquitin-like domain-containing protein.	0.402
K5VWK2_AGABU	K5W7E6_AGABU	K5VWK2	K5W7E6	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.807
K5VWK2_AGABU	K5X7H8_AGABU	K5VWK2	K5X7H8	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.995
K5VWK2_AGABU	K5XEW1_AGABU	K5VWK2	K5XEW1	Serine/threonine-protein phosphatase.	Ubiquitin-like domain-containing protein.	0.579
K5VWK2_AGABU	K5XJP2_AGABU	K5VWK2	K5XJP2	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.630
K5VZQ9_AGABU	K5XEW1_AGABU	K5VZQ9	K5XEW1	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.693
K5VZQ9_AGABU	K5XJP2_AGABU	K5VZQ9	K5XJP2	Uncharacterized protein.	Uncharacterized protein.	0.422
K5W0C4_AGABU	K5W1R2_AGABU	K5W0C4	K5W1R2	BZIP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.776
K5W0C4_AGABU	K5W4V4_AGABU	K5W0C4	K5W4V4	BZIP domain-containing protein.	Mitogen-activated protein kinase.	0.776
K5W0C4_AGABU	K5X265_AGABU	K5W0C4	K5X265	BZIP domain-containing protein.	Uncharacterized protein.	0.872
K5W0C4_AGABU	K5X2E2_AGABU	K5W0C4	K5X2E2	BZIP domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.764
K5W0C4_AGABU	K5XBK0_AGABU	K5W0C4	K5XBK0	BZIP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.570