(28 nodes) Fatty acid metabolism network (Agaricus bisporus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

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protein homology

Your Input:
	K5VP72_AGABU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
	K5VUH0_AGABU	Carrier domain-containing protein. (3931 aa)
	K5W8U0_AGABU	AMP-binding domain-containing protein. (697 aa)
	K5WAD7_AGABU	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (673 aa)
	K5WJB4_AGABU	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (677 aa)
	K5WPV1_AGABU	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (685 aa)
	K5WXW7_AGABU	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (467 aa)
	K5WY50_AGABU	Uncharacterized protein. (418 aa)
	K5WZ39_AGABU	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (297 aa)
	K5WZC9_AGABU	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (261 aa)
	K5X1H7_AGABU	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa)
	K5X511_AGABU	AMP-binding domain-containing protein. (571 aa)
	K5X7Z3_AGABU	Cytochrome b5 heme-binding domain-containing protein. (392 aa)
	K5X8E2_AGABU	Uncharacterized protein. (253 aa)
	K5X8T4_AGABU	Uncharacterized protein. (291 aa)
	K5X8Z8_AGABU	AMP-binding domain-containing protein. (653 aa)
	K5XBT2_AGABU	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (332 aa)
	K5XBZ2_AGABU	Uncharacterized protein. (314 aa)
	K5XG90_AGABU	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	K5XHP0_AGABU	AMP-binding domain-containing protein. (692 aa)
	K5XJ55_AGABU	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
	K5XKL6_AGABU	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
	K5XNF3_AGABU	AMP-binding domain-containing protein. (682 aa)
	K5XRW3_AGABU	Uncharacterized protein. (563 aa)
	K5XRY1_AGABU	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (430 aa)
	K5XW41_AGABU	FA_desaturase domain-containing protein. (439 aa)
	K5XYC4_AGABU	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
	K5XYP5_AGABU	Uncharacterized protein. (452 aa)

Your Current Organism:

Agaricus bisporus

NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K5VP72_AGABU	K5VUH0_AGABU	K5VP72	K5VUH0	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Carrier domain-containing protein.	0.903
K5VUH0_AGABU	K5VP72_AGABU	K5VUH0	K5VP72	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.903
K5VUH0_AGABU	K5W8U0_AGABU	K5VUH0	K5W8U0	Carrier domain-containing protein.	AMP-binding domain-containing protein.	0.913
K5VUH0_AGABU	K5WXW7_AGABU	K5VUH0	K5WXW7	Carrier domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.428
K5VUH0_AGABU	K5X1H7_AGABU	K5VUH0	K5X1H7	Carrier domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.903
K5VUH0_AGABU	K5X511_AGABU	K5VUH0	K5X511	Carrier domain-containing protein.	AMP-binding domain-containing protein.	0.913
K5VUH0_AGABU	K5X8E2_AGABU	K5VUH0	K5X8E2	Carrier domain-containing protein.	Uncharacterized protein.	0.910
K5VUH0_AGABU	K5X8T4_AGABU	K5VUH0	K5X8T4	Carrier domain-containing protein.	Uncharacterized protein.	0.910
K5VUH0_AGABU	K5X8Z8_AGABU	K5VUH0	K5X8Z8	Carrier domain-containing protein.	AMP-binding domain-containing protein.	0.913
K5VUH0_AGABU	K5XHP0_AGABU	K5VUH0	K5XHP0	Carrier domain-containing protein.	AMP-binding domain-containing protein.	0.913
K5VUH0_AGABU	K5XNF3_AGABU	K5VUH0	K5XNF3	Carrier domain-containing protein.	AMP-binding domain-containing protein.	0.913
K5W8U0_AGABU	K5VUH0_AGABU	K5W8U0	K5VUH0	AMP-binding domain-containing protein.	Carrier domain-containing protein.	0.913
K5W8U0_AGABU	K5WJB4_AGABU	K5W8U0	K5WJB4	AMP-binding domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.583
K5W8U0_AGABU	K5WPV1_AGABU	K5W8U0	K5WPV1	AMP-binding domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.583
K5W8U0_AGABU	K5WXW7_AGABU	K5W8U0	K5WXW7	AMP-binding domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.492
K5W8U0_AGABU	K5WY50_AGABU	K5W8U0	K5WY50	AMP-binding domain-containing protein.	Uncharacterized protein.	0.448
K5W8U0_AGABU	K5X511_AGABU	K5W8U0	K5X511	AMP-binding domain-containing protein.	AMP-binding domain-containing protein.	0.932
K5W8U0_AGABU	K5X7Z3_AGABU	K5W8U0	K5X7Z3	AMP-binding domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein.	0.492
K5W8U0_AGABU	K5X8Z8_AGABU	K5W8U0	K5X8Z8	AMP-binding domain-containing protein.	AMP-binding domain-containing protein.	0.943
K5W8U0_AGABU	K5XBZ2_AGABU	K5W8U0	K5XBZ2	AMP-binding domain-containing protein.	Uncharacterized protein.	0.919