(20 nodes) Mixed, incl. Nonhomologous end joining complex, and Single strand break repair network (Habropoda laboriosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WH47_09756	DNA ligase 4; Belongs to the ATP-dependent DNA ligase family. (872 aa)
	WH47_10576	X-ray repair cross-complementing protein 5. (554 aa)
	WH47_05677	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (337 aa)
	WH47_04191	Bifunctional polynucleotide phosphatase/kinase. (502 aa)
	WH47_04195	DNA ligase. (997 aa)
	WH47_02461	Uncharacterized protein. (502 aa)
	WH47_02627	Ubiquitin carboxyl-terminal hydrolase 47. (1223 aa)
	WH47_04722	Aprataxin and PNK-like factor. (364 aa)
	WH47_01956	Aprataxin. (184 aa)
	WH47_02925	Uncharacterized protein. (312 aa)
	WH47_01590	UPF0609 protein. (463 aa)
	WH47_01068	Uncharacterized protein. (226 aa)
	WH47_12029	Transcription termination factor 2. (959 aa)
	WH47_10098	DNA repair protein XRCC1. (490 aa)
	WH47_11703	Poly [ADP-ribose] polymerase. (992 aa)
	WH47_07586	Uncharacterized protein C16orf48 like protein. (391 aa)
	WH47_08164	DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3670 aa)
	WH47_06808	Poly(ADP-ribose) glycohydrolase. (921 aa)
	WH47_05894	Protein FAM162B. (115 aa)
	WH47_00070	Putative tyrosyl-DNA phosphodiesterase. (655 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WH47_00070	WH47_01956	A0A0L7RKH2	A0A0L7QY36	Putative tyrosyl-DNA phosphodiesterase.	Aprataxin.	0.735
WH47_00070	WH47_04191	A0A0L7RKH2	A0A0L7QV67	Putative tyrosyl-DNA phosphodiesterase.	Bifunctional polynucleotide phosphatase/kinase.	0.723
WH47_00070	WH47_04195	A0A0L7RKH2	A0A0L7QVE8	Putative tyrosyl-DNA phosphodiesterase.	DNA ligase.	0.838
WH47_00070	WH47_04722	A0A0L7RKH2	A0A0L7QXC6	Putative tyrosyl-DNA phosphodiesterase.	Aprataxin and PNK-like factor.	0.740
WH47_00070	WH47_05677	A0A0L7RKH2	A0A0L7QQR3	Putative tyrosyl-DNA phosphodiesterase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.809
WH47_00070	WH47_07586	A0A0L7RKH2	A0A0L7RE89	Putative tyrosyl-DNA phosphodiesterase.	Uncharacterized protein C16orf48 like protein.	0.619
WH47_00070	WH47_08164	A0A0L7RKH2	A0A0L7RGG9	Putative tyrosyl-DNA phosphodiesterase.	DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.772
WH47_00070	WH47_09756	A0A0L7RKH2	A0A0L7QMF4	Putative tyrosyl-DNA phosphodiesterase.	DNA ligase 4; Belongs to the ATP-dependent DNA ligase family.	0.760
WH47_00070	WH47_10098	A0A0L7RKH2	A0A0L7R3U2	Putative tyrosyl-DNA phosphodiesterase.	DNA repair protein XRCC1.	0.778
WH47_00070	WH47_10576	A0A0L7RKH2	A0A0L7QMM9	Putative tyrosyl-DNA phosphodiesterase.	X-ray repair cross-complementing protein 5.	0.826
WH47_00070	WH47_11703	A0A0L7RKH2	A0A0L7R840	Putative tyrosyl-DNA phosphodiesterase.	Poly [ADP-ribose] polymerase.	0.557
WH47_01068	WH47_01590	A0A0L7R0V9	A0A0L7R0N9	Uncharacterized protein.	UPF0609 protein.	0.824
WH47_01068	WH47_01956	A0A0L7R0V9	A0A0L7QY36	Uncharacterized protein.	Aprataxin.	0.540
WH47_01068	WH47_04191	A0A0L7R0V9	A0A0L7QV67	Uncharacterized protein.	Bifunctional polynucleotide phosphatase/kinase.	0.420
WH47_01068	WH47_04195	A0A0L7R0V9	A0A0L7QVE8	Uncharacterized protein.	DNA ligase.	0.509
WH47_01068	WH47_04722	A0A0L7R0V9	A0A0L7QXC6	Uncharacterized protein.	Aprataxin and PNK-like factor.	0.558
WH47_01068	WH47_05677	A0A0L7R0V9	A0A0L7QQR3	Uncharacterized protein.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.723
WH47_01068	WH47_05894	A0A0L7R0V9	A0A0L7RK98	Uncharacterized protein.	Protein FAM162B.	0.471
WH47_01068	WH47_06808	A0A0L7R0V9	A0A0L7RIY4	Uncharacterized protein.	Poly(ADP-ribose) glycohydrolase.	0.922
WH47_01068	WH47_07586	A0A0L7R0V9	A0A0L7RE89	Uncharacterized protein.	Uncharacterized protein C16orf48 like protein.	0.723