(13 nodes) G0 and Early G1, and Drug-mediated inhibition of CDK4/CDK6 activity network (Habropoda laboriosa)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	WH47_08734	G1/S-specific cyclin-E; Belongs to the cyclin family. (466 aa)
	WH47_05645	Retinoblastoma-like protein 1. (882 aa)
	WH47_01164	Transcription factor E2F5. (293 aa)
	WH47_00358	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (53 aa)
	WH47_04630	G1/S-specific cyclin-D2. (301 aa)
	WH47_10220	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (299 aa)
	WH47_07239	Cyclin-A2; Belongs to the cyclin family. (103 aa)
	WH47_07238	G2/mitotic-specific cyclin-A. (286 aa)
	WH47_08871	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (463 aa)
	WH47_11969	Uncharacterized protein. (224 aa)
	WH47_12428	Transcription factor Dp-1. (502 aa)
	WH47_10805	Uncharacterized protein. (141 aa)
	WH47_07065	Transcription factor E2F2. (450 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WH47_00358	WH47_01164	A0A0L7R1X4	A0A0L7QYX9	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Transcription factor E2F5.	0.714
WH47_00358	WH47_04630	A0A0L7R1X4	A0A0L7R2D6	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	G1/S-specific cyclin-D2.	0.902
WH47_00358	WH47_05645	A0A0L7R1X4	A0A0L7QQH1	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Retinoblastoma-like protein 1.	0.792
WH47_00358	WH47_07065	A0A0L7R1X4	A0A0L7RG92	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Transcription factor E2F2.	0.665
WH47_00358	WH47_07238	A0A0L7R1X4	A0A0L7R5S8	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	G2/mitotic-specific cyclin-A.	0.960
WH47_00358	WH47_07239	A0A0L7R1X4	A0A0L7R5K8	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-A2; Belongs to the cyclin family.	0.960
WH47_00358	WH47_08734	A0A0L7R1X4	A0A0L7QP46	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	G1/S-specific cyclin-E; Belongs to the cyclin family.	0.843
WH47_00358	WH47_08871	A0A0L7R1X4	A0A0L7R6K4	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.957
WH47_00358	WH47_10220	A0A0L7R1X4	A0A0L7R4I8	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.957
WH47_00358	WH47_10805	A0A0L7R1X4	A0A0L7RCV1	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Uncharacterized protein.	0.969
WH47_00358	WH47_11969	A0A0L7R1X4	A0A0L7R7Q4	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Uncharacterized protein.	0.913
WH47_00358	WH47_12428	A0A0L7R1X4	A0A0L7R8B5	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Transcription factor Dp-1.	0.767
WH47_01164	WH47_00358	A0A0L7QYX9	A0A0L7R1X4	Transcription factor E2F5.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.714
WH47_01164	WH47_04630	A0A0L7QYX9	A0A0L7R2D6	Transcription factor E2F5.	G1/S-specific cyclin-D2.	0.839
WH47_01164	WH47_05645	A0A0L7QYX9	A0A0L7QQH1	Transcription factor E2F5.	Retinoblastoma-like protein 1.	0.993
WH47_01164	WH47_07065	A0A0L7QYX9	A0A0L7RG92	Transcription factor E2F5.	Transcription factor E2F2.	0.962
WH47_01164	WH47_07238	A0A0L7QYX9	A0A0L7R5S8	Transcription factor E2F5.	G2/mitotic-specific cyclin-A.	0.848
WH47_01164	WH47_07239	A0A0L7QYX9	A0A0L7R5K8	Transcription factor E2F5.	Cyclin-A2; Belongs to the cyclin family.	0.848
WH47_01164	WH47_08734	A0A0L7QYX9	A0A0L7QP46	Transcription factor E2F5.	G1/S-specific cyclin-E; Belongs to the cyclin family.	0.893
WH47_01164	WH47_08871	A0A0L7QYX9	A0A0L7R6K4	Transcription factor E2F5.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.790