(43 nodes) Regulation of epithelial cell migration network (Habropoda laboriosa)

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second shell of interactors

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proteins of unknown 3D structure

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	WH47_05924	Receptor protein-tyrosine kinase. (1373 aa)
	WH47_06723	Protein vein. (415 aa)
	WH47_04950	Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1994 aa)
	WH47_07935	Zinc transporter SLC39A7. (399 aa)
	WH47_06725	Pro-neuregulin-2, membrane-bound isoform. (187 aa)
	WH47_00371	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (831 aa)
	WH47_10930	Serine/threonine-protein kinase mig-15. (1256 aa)
	WH47_08464	Bone morphogenetic protein 10. (337 aa)
	WH47_08472	Insulin receptor substrate 1-B. (1227 aa)
	WH47_04368	Phosphoinositide phospholipase C. (1167 aa)
	WH47_06700	Protein sprint. (1377 aa)
	WH47_06098	GTP cyclohydrolase 1. (269 aa)
	WH47_05447	Protein patched. (1328 aa)
	WH47_01859	DnaJ like protein subfamily C member 13. (2177 aa)
	WH47_04049	Neuroligin-4, Y-linked. (776 aa)
	WH47_04163	Non-specific serine/threonine protein kinase. (525 aa)
	WH47_04268	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
	WH47_03725	Protein spitz. (216 aa)
	WH47_02701	Tyrosine-protein phosphatase non-receptor type 4. (898 aa)
	WH47_00765	F-box/WD repeat-containing protein 1A. (538 aa)
	WH47_12542	Tyrosine kinase receptor Cad96Ca; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1667 aa)
	WH47_01556	Slit like protein 2 protein. (949 aa)
	WH47_00295	Dual specificity protein phosphatase 10. (330 aa)
	WH47_00294	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (258 aa)
	WH47_04707	Protein slit. (1394 aa)
	WH47_00529	Paired amphipathic helix protein Sin3a. (1471 aa)
	WH47_10137	Protein virilizer. (1489 aa)
	WH47_10200	Disintegrin and metalloproteinase domain-containing protein 10. (979 aa)
	WH47_10301	Signal transducing adapter molecule 1. (491 aa)
	WH47_12749	Mitogen-activated protein kinase. (593 aa)
	WH47_12789	Dual specificity mitogen-activated protein kinase kinase 7. (756 aa)
	WH47_01436	Origin recognition complex subunit 3. (652 aa)
	WH47_01018	Angio-associated migratory cell protein. (414 aa)
	WH47_08959	Heterogeneous nuclear ribonucleoprotein 27C. (396 aa)
	WH47_11818	Ras-responsive element-binding protein 1. (1456 aa)
	WH47_11592	Tyrosine 3-monooxygenase. (528 aa)
	WH47_10387	Nuclear receptor coactivator 2. (1612 aa)
	WH47_03240	Apoptosis 1 inhibitor. (401 aa)
	WH47_03221	Non-specific serine/threonine protein kinase. (1146 aa)
	WH47_03311	E3 ubiquitin-protein ligase CBL. (454 aa)
	WH47_03313	UBA domain-containing protein. (290 aa)
	WH47_10779	Roundabout like protein 2. (1339 aa)
	WH47_09644	CCAAT/enhancer-binding protein. (362 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WH47_00294	WH47_03240	A0A0L7R1W1	A0A0L7RAY5	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Apoptosis 1 inhibitor.	0.491
WH47_00294	WH47_04163	A0A0L7R1W1	A0A0L7QV36	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Non-specific serine/threonine protein kinase.	0.448
WH47_00294	WH47_04268	A0A0L7R1W1	A0A0L7QVD9	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	0.496
WH47_00294	WH47_12749	A0A0L7R1W1	A0A0L7R4Z0	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.988
WH47_00294	WH47_12789	A0A0L7R1W1	A0A0L7R527	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity mitogen-activated protein kinase kinase 7.	0.711
WH47_00295	WH47_03240	A0A0L7R1R1	A0A0L7RAY5	Dual specificity protein phosphatase 10.	Apoptosis 1 inhibitor.	0.491
WH47_00295	WH47_04163	A0A0L7R1R1	A0A0L7QV36	Dual specificity protein phosphatase 10.	Non-specific serine/threonine protein kinase.	0.448
WH47_00295	WH47_04268	A0A0L7R1R1	A0A0L7QVD9	Dual specificity protein phosphatase 10.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	0.496
WH47_00295	WH47_12749	A0A0L7R1R1	A0A0L7R4Z0	Dual specificity protein phosphatase 10.	Mitogen-activated protein kinase.	0.960
WH47_00295	WH47_12789	A0A0L7R1R1	A0A0L7R527	Dual specificity protein phosphatase 10.	Dual specificity mitogen-activated protein kinase kinase 7.	0.711
WH47_00371	WH47_02701	A0A0L7QKE3	A0A0L7QX47	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Tyrosine-protein phosphatase non-receptor type 4.	0.715
WH47_00371	WH47_03311	A0A0L7QKE3	A0A0L7RBD8	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	E3 ubiquitin-protein ligase CBL.	0.663
WH47_00371	WH47_03313	A0A0L7QKE3	A0A0L7RBG2	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	UBA domain-containing protein.	0.663
WH47_00371	WH47_10301	A0A0L7QKE3	A0A0L7R4V1	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Signal transducing adapter molecule 1.	0.997
WH47_00529	WH47_10387	A0A0L7R406	A0A0L7R9R6	Paired amphipathic helix protein Sin3a.	Nuclear receptor coactivator 2.	0.698
WH47_00765	WH47_04163	A0A0L7QYS1	A0A0L7QV36	F-box/WD repeat-containing protein 1A.	Non-specific serine/threonine protein kinase.	0.685
WH47_00765	WH47_10387	A0A0L7QYS1	A0A0L7R9R6	F-box/WD repeat-containing protein 1A.	Nuclear receptor coactivator 2.	0.483
WH47_01556	WH47_10779	A0A0L7R0M7	A0A0L7RDF4	Slit like protein 2 protein.	Roundabout like protein 2.	0.959
WH47_02701	WH47_00371	A0A0L7QX47	A0A0L7QKE3	Tyrosine-protein phosphatase non-receptor type 4.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.715
WH47_02701	WH47_03311	A0A0L7QX47	A0A0L7RBD8	Tyrosine-protein phosphatase non-receptor type 4.	E3 ubiquitin-protein ligase CBL.	0.685