(14 nodes) Histone ubiquitination network (Habropoda laboriosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WH47_11875	E3 ubiquitin protein ligase. (960 aa)
	WH47_06307	E3 ubiquitin-protein ligase RING2. (380 aa)
	WH47_08258	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	WH47_08361	E3 ubiquitin-protein ligase RNF8-A. (447 aa)
	WH47_11879	E3 ubiquitin-protein ligase TRIM37. (1023 aa)
	WH47_00456	Polycomb complex protein BMI-1. (1402 aa)
	WH47_08847	Polycomb group protein Psc. (1364 aa)
	WH47_08848	Polycomb group RING finger protein 2. (781 aa)
	WH47_02027	WW domain-containing adapter protein with coiled-coil. (458 aa)
	WH47_04525	JmjC domain-containing histone demethylation protein 1. (983 aa)
	Sgf11	SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (329 aa)
	WH47_08113	Transcription initiation factor TFIID subunit 1. (176 aa)
	WH47_08112	Transcription initiation factor TFIID subunit 1. (1697 aa)
	WH47_10558	Polycomb group RING finger protein 3. (230 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Sgf11	WH47_11879	A0A0L7QXD8	A0A0L7R8L2	SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.	E3 ubiquitin-protein ligase TRIM37.	0.431
WH47_00456	WH47_04525	A0A0L7R7F2	A0A0L7R2D8	Polycomb complex protein BMI-1.	JmjC domain-containing histone demethylation protein 1.	0.911
WH47_00456	WH47_06307	A0A0L7R7F2	A0A0L7RCN9	Polycomb complex protein BMI-1.	E3 ubiquitin-protein ligase RING2.	0.963
WH47_00456	WH47_08258	A0A0L7R7F2	A0A0L7RG96	Polycomb complex protein BMI-1.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.545
WH47_00456	WH47_08848	A0A0L7R7F2	A0A0L7R6F2	Polycomb complex protein BMI-1.	Polycomb group RING finger protein 2.	0.675
WH47_00456	WH47_10558	A0A0L7R7F2	A0A0L7QMU2	Polycomb complex protein BMI-1.	Polycomb group RING finger protein 3.	0.672
WH47_02027	WH47_08258	A0A0L7R2R0	A0A0L7RG96	WW domain-containing adapter protein with coiled-coil.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.694
WH47_02027	WH47_11875	A0A0L7R2R0	A0A0L7R8R2	WW domain-containing adapter protein with coiled-coil.	E3 ubiquitin protein ligase.	0.896
WH47_04525	WH47_00456	A0A0L7R2D8	A0A0L7R7F2	JmjC domain-containing histone demethylation protein 1.	Polycomb complex protein BMI-1.	0.911
WH47_04525	WH47_06307	A0A0L7R2D8	A0A0L7RCN9	JmjC domain-containing histone demethylation protein 1.	E3 ubiquitin-protein ligase RING2.	0.994
WH47_04525	WH47_08847	A0A0L7R2D8	A0A0L7R6K2	JmjC domain-containing histone demethylation protein 1.	Polycomb group protein Psc.	0.915
WH47_04525	WH47_08848	A0A0L7R2D8	A0A0L7R6F2	JmjC domain-containing histone demethylation protein 1.	Polycomb group RING finger protein 2.	0.924
WH47_04525	WH47_10558	A0A0L7R2D8	A0A0L7QMU2	JmjC domain-containing histone demethylation protein 1.	Polycomb group RING finger protein 3.	0.926
WH47_06307	WH47_00456	A0A0L7RCN9	A0A0L7R7F2	E3 ubiquitin-protein ligase RING2.	Polycomb complex protein BMI-1.	0.963
WH47_06307	WH47_04525	A0A0L7RCN9	A0A0L7R2D8	E3 ubiquitin-protein ligase RING2.	JmjC domain-containing histone demethylation protein 1.	0.994
WH47_06307	WH47_08258	A0A0L7RCN9	A0A0L7RG96	E3 ubiquitin-protein ligase RING2.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.646
WH47_06307	WH47_08847	A0A0L7RCN9	A0A0L7R6K2	E3 ubiquitin-protein ligase RING2.	Polycomb group protein Psc.	0.974
WH47_06307	WH47_08848	A0A0L7RCN9	A0A0L7R6F2	E3 ubiquitin-protein ligase RING2.	Polycomb group RING finger protein 2.	0.974
WH47_06307	WH47_10558	A0A0L7RCN9	A0A0L7QMU2	E3 ubiquitin-protein ligase RING2.	Polycomb group RING finger protein 3.	0.973
WH47_08112	WH47_08113	A0A0L7QNA2	A0A0L7QND0	Transcription initiation factor TFIID subunit 1.	Transcription initiation factor TFIID subunit 1.	0.466