(14 nodes) Canonical Wnt signaling pathway network (Habropoda laboriosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WH47_06534	Protein chibby like protein 1. (103 aa)
	WH47_03904	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
	WH47_02692	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
	WH47_09838	Protein BCL9 like protein. (1156 aa)
	WH47_08215	Protein pangolin, isoforms A/H/I. (157 aa)
	WH47_00533	Segment polarity protein dishevelled like protein DVL-3. (663 aa)
	WH47_08220	Protein pangolin, isoform J. (978 aa)
	WH47_03264	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (430 aa)
	WH47_11487	Protein pygopus. (500 aa)
	WH47_03011	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (662 aa)
	WH47_01873	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (425 aa)
	WH47_08986	Armadillo segment polarity protein. (812 aa)
	WH47_00436	Low-density lipoprotein receptor-related protein 5. (1633 aa)
	WH47_03261	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WH47_00436	WH47_00533	A0A0L7R7D2	A0A0L7R3Y8	Low-density lipoprotein receptor-related protein 5.	Segment polarity protein dishevelled like protein DVL-3.	0.972
WH47_00436	WH47_01873	A0A0L7R7D2	A0A0L7QUE1	Low-density lipoprotein receptor-related protein 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.965
WH47_00436	WH47_02692	A0A0L7R7D2	A0A0L7QX34	Low-density lipoprotein receptor-related protein 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.939
WH47_00436	WH47_03011	A0A0L7R7D2	A0A0L7QT69	Low-density lipoprotein receptor-related protein 5.	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.965
WH47_00436	WH47_03261	A0A0L7R7D2	A0A0L7RB86	Low-density lipoprotein receptor-related protein 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.965
WH47_00436	WH47_03264	A0A0L7R7D2	A0A0L7RBI4	Low-density lipoprotein receptor-related protein 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.929
WH47_00436	WH47_03904	A0A0L7R7D2	A0A0L7QUK5	Low-density lipoprotein receptor-related protein 5.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.604
WH47_00436	WH47_08986	A0A0L7R7D2	A0A0L7R6W9	Low-density lipoprotein receptor-related protein 5.	Armadillo segment polarity protein.	0.709
WH47_00533	WH47_00436	A0A0L7R3Y8	A0A0L7R7D2	Segment polarity protein dishevelled like protein DVL-3.	Low-density lipoprotein receptor-related protein 5.	0.972
WH47_00533	WH47_01873	A0A0L7R3Y8	A0A0L7QUE1	Segment polarity protein dishevelled like protein DVL-3.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.784
WH47_00533	WH47_02692	A0A0L7R3Y8	A0A0L7QX34	Segment polarity protein dishevelled like protein DVL-3.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.784
WH47_00533	WH47_03011	A0A0L7R3Y8	A0A0L7QT69	Segment polarity protein dishevelled like protein DVL-3.	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.977
WH47_00533	WH47_03261	A0A0L7R3Y8	A0A0L7RB86	Segment polarity protein dishevelled like protein DVL-3.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.784
WH47_00533	WH47_03264	A0A0L7R3Y8	A0A0L7RBI4	Segment polarity protein dishevelled like protein DVL-3.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.805
WH47_00533	WH47_08986	A0A0L7R3Y8	A0A0L7R6W9	Segment polarity protein dishevelled like protein DVL-3.	Armadillo segment polarity protein.	0.900
WH47_01873	WH47_00436	A0A0L7QUE1	A0A0L7R7D2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Low-density lipoprotein receptor-related protein 5.	0.965
WH47_01873	WH47_00533	A0A0L7QUE1	A0A0L7R3Y8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Segment polarity protein dishevelled like protein DVL-3.	0.784
WH47_01873	WH47_03011	A0A0L7QUE1	A0A0L7QT69	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.972
WH47_01873	WH47_03264	A0A0L7QUE1	A0A0L7RBI4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.549
WH47_01873	WH47_03904	A0A0L7QUE1	A0A0L7QUK5	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.540