(92 nodes) Glycerophospholipid metabolism network (Habropoda laboriosa)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	WH47_07197	Choline O-acetyltransferase. (555 aa)
	WH47_00798	Diacylglycerol kinase. (531 aa)
	WH47_00806	RNA-directed DNA polymerase from mobile element jockey. (277 aa)
	WH47_11448	Phosphatidylinositol transfer protein alpha isoform. (276 aa)
	WH47_10987	Diacylglycerol kinase. (920 aa)
	WH47_10995	Lysophospholipid acyltransferase 2; Belongs to the membrane-bound acyltransferase family. (480 aa)
	WH47_10986	Eye-specific diacylglycerol kinase. (470 aa)
	WH47_08663	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (444 aa)
	WH47_05725	Dihydroxyacetone phosphate acyltransferase. (587 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (974 aa)
	WH47_07136	Choline/ethanolaminephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (494 aa)
	WH47_04335	Ethanolamine-phosphate cytidylyltransferase. (373 aa)
	WH47_07093	Uncharacterized protein. (86 aa)
	WH47_05778	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (474 aa)
	WH47_05746	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (753 aa)
	WH47_05777	Acetylcholinesterase. (423 aa)
	WH47_03034	Ancient ubiquitous protein 1. (378 aa)
	WH47_05879	Putative complex I intermediate-associated protein 30, mitochondrial. (282 aa)
	WH47_01872	Regulator of microtubule dynamics protein 1. (245 aa)
	WH47_01816	Choline-phosphate cytidylyltransferase B. (402 aa)
	WH47_01831	Extended synaptotagmin-2. (805 aa)
	WH47_05880	Putative cardiolipin synthase. (285 aa)
	WH47_05193	Protein NDRG3. (470 aa)
	WH47_03801	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (188 aa)
	WH47_04118	Phospholipase A2 isozymes PA3A/PA3B/PA5. (255 aa)
	WH47_03812	Phospholipase A1 member A. (291 aa)
	WH47_04178	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (617 aa)
	WH47_05282	Glycerol-3-phosphate acyltransferase 3-like. (581 aa)
	WH47_04836	Phosphatidylserine synthase 1. (462 aa)
	WH47_04868	Phospholipase A1 member A. (355 aa)
	WH47_03878	Phosphatidylserine decarboxylase proenzyme. (378 aa)
	WH47_02685	Tafazzin family protein; Belongs to the taffazin family. (284 aa)
	WH47_03711	Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (457 aa)
	WH47_03146	Coiled-coil domain-containing protein 115. (167 aa)
	WH47_03083	Ubiquitin thioesterase otubain-like. (264 aa)
	WH47_00746	Spondin domain-containing protein. (149 aa)
	WH47_00744	Spondin-2. (464 aa)
	WH47_00766	Phosphatidate phosphatase PPAPDC1A. (191 aa)
	WH47_00770	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (840 aa)
	WH47_01121	Glycerophosphocholine phosphodiesterase GPCPD1. (809 aa)
	WH47_01132	Carnitine O-acetyltransferase. (470 aa)
	WH47_01523	Cytoplasmic phosphatidylinositol transfer protein 1. (252 aa)
	WH47_01535	Ethanolaminephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (391 aa)
	WH47_01095	1-acylglycerophosphocholine O-acyltransferase 1. (579 aa)
	WH47_00262	Group 3 secretory phospholipase A2. (339 aa)
	WH47_00214	Protein HEXIM1. (398 aa)
	WH47_04627	Spondin-1. (832 aa)
	WH47_04640	Phospholipase A(2). (125 aa)
	WH47_09986	Lipid phosphate phosphohydrolase 1. (315 aa)
	WH47_10293	Putative phosphatidate phosphatase. (271 aa)
	WH47_12837	Neuropathy target esterase sws. (1296 aa)
	WH47_12775	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (218 aa)
	WH47_08852	Phospholipase A2. (182 aa)
	WH47_11712	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
	WH47_11824	Small proline-rich protein 3. (100 aa)
	WH47_09285	Tricalbin-1. (1163 aa)
	WH47_10486	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (513 aa)
	WH47_03186	Phospholipase D3. (671 aa)
	WH47_03216	Group XV phospholipase A2. (384 aa)
	WH47_03357	Cat eye syndrome critical region protein 5 like protein. (374 aa)
	WH47_03536	Diacylglycerol kinase. (840 aa)
	WH47_03568	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (365 aa)
	WH47_06559	Group XIIA secretory phospholipase A2. (206 aa)
	WH47_06497	Nucleolar protein 11-like. (449 aa)
	WH47_06518	Mitochondrial cardiolipin hydrolase. (180 aa)
	WH47_10782	Choline/ethanolamine kinase. (372 aa)
	WH47_06533	85 kDa calcium-independent phospholipase A2. (793 aa)
	WH47_07563	DDE_Tnp_1_7 domain-containing protein. (192 aa)
	WH47_07584	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (252 aa)
	WH47_09342	Lysophospholipid acyltransferase 7; Belongs to the membrane-bound acyltransferase family. (464 aa)
	WH47_09392	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (476 aa)
	WH47_08437	Uncharacterized protein. (598 aa)
	WH47_05556	Ethanolamine kinase. (348 aa)
	WH47_08531	1-acyl-sn-glycerol-3-phosphate acyltransferase gamma. (302 aa)
	WH47_06958	Phospholipase. (1107 aa)
	WH47_00628	SEC23-interacting protein. (1441 aa)
	WH47_03585	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (365 aa)
	WH47_06754	Acyl-protein thioesterase 1. (153 aa)
	WH47_06769	Phospholipase A2. (232 aa)
	WH47_06778	Glycerophosphodiester phosphodiesterase 1. (361 aa)
	WH47_06816	Phosphatidate phosphatase LPIN2. (1062 aa)
	WH47_05240	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (419 aa)
	WH47_05241	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic. (173 aa)
	WH47_00060	Uncharacterized protein. (185 aa)
	WH47_00077	Spondin-1. (688 aa)
	WH47_00062	Uncharacterized protein. (133 aa)
	WH47_01754	Lysocardiolipin acyltransferase 1. (755 aa)
	WH47_00064	Uncharacterized protein. (499 aa)
	WH47_02151	Protein retinal degeneration B. (1256 aa)
	WH47_01755	Phospholipase DDHD1. (584 aa)
	WH47_07189	Phospholipase B1, membrane-associated. (372 aa)
	WH47_07190	Phospholipase B1, membrane-associated. (451 aa)

Your Current Organism:

Habropoda laboriosa

NCBI taxonomy Id: 597456
Other names: H. laboriosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED16	WH47_00798	A0A0L7QQV9	A0A0L7QK09	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Diacylglycerol kinase.	0.435
MED16	WH47_01095	A0A0L7QQV9	A0A0L7R134	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	1-acylglycerophosphocholine O-acyltransferase 1.	0.537
MED16	WH47_01535	A0A0L7QQV9	A0A0L7R0J2	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Ethanolaminephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.467
MED16	WH47_01754	A0A0L7QQV9	A0A0L7RK49	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Lysocardiolipin acyltransferase 1.	0.540
MED16	WH47_01872	A0A0L7QQV9	A0A0L7QTY1	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Regulator of microtubule dynamics protein 1.	0.540
MED16	WH47_03034	A0A0L7QQV9	A0A0L7QT10	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Ancient ubiquitous protein 1.	0.555
MED16	WH47_03186	A0A0L7QQV9	A0A0L7RB09	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Phospholipase D3.	0.517
MED16	WH47_03216	A0A0L7QQV9	A0A0L7RB39	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Group XV phospholipase A2.	0.709
MED16	WH47_03536	A0A0L7QQV9	A0A0L7RC29	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Diacylglycerol kinase.	0.437
MED16	WH47_03585	A0A0L7QQV9	A0A0L7RIB0	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1.	0.540
MED16	WH47_03801	A0A0L7QQV9	A0A0L7QUT3	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.736
MED16	WH47_05240	A0A0L7QQV9	A0A0L7RKN2	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.422
MED16	WH47_05241	A0A0L7QQV9	A0A0L7RKL2	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic.	0.422
MED16	WH47_05282	A0A0L7QQV9	A0A0L7QVJ6	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Glycerol-3-phosphate acyltransferase 3-like.	0.555
MED16	WH47_05725	A0A0L7QQV9	A0A0L7QQP5	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Dihydroxyacetone phosphate acyltransferase.	0.539
MED16	WH47_05746	A0A0L7QQV9	A0A0L7QSS0	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.703
MED16	WH47_05880	A0A0L7QQV9	A0A0L7QU57	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Putative cardiolipin synthase.	0.709
MED16	WH47_06518	A0A0L7QQV9	A0A0L7RD98	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mitochondrial cardiolipin hydrolase.	0.650
MED16	WH47_06816	A0A0L7QQV9	A0A0L7RJ49	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Phosphatidate phosphatase LPIN2.	0.686
MED16	WH47_06958	A0A0L7QQV9	A0A0L7RHA9	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Phospholipase.	0.670