STRINGSTRING
ANA80844.1 ANA80844.1 ANA81024.1 ANA81024.1 ANA81230.1 ANA81230.1 ANA81426.1 ANA81426.1 ruvA ruvA aspS aspS ANA81500.1 ANA81500.1 ANA81584.1 ANA81584.1 ANA81625.1 ANA81625.1 recO recO rsgA-2 rsgA-2 recG recG metG-2 metG-2 efp efp ANA82021.1 ANA82021.1 asnS asnS polC polC nusA nusA pnp pnp ANA78688.1 ANA78688.1 ANA78820.1 ANA78820.1 pheT pheT ANA83322.1 ANA83322.1 ANA79261.1 ANA79261.1 ANA79551.1 ANA79551.1 infA infA rpsQ rpsQ rplB rplB rpsL rpsL ligA ligA ANA79771.1 ANA79771.1 ANA80148.1 ANA80148.1 ANA82650.1 ANA82650.1 lysS lysS ANA80233.1 ANA80233.1 rho rho ANA80310.1 ANA80310.1 rnr rnr ANA80463.1 ANA80463.1 ANA80647.1 ANA80647.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANA80844.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (351 aa)
ANA81024.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (502 aa)
ANA81230.123S rRNA (uracil-5-)-methyltransferase RumA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (530 aa)
ANA81426.1Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
aspSaspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (591 aa)
ANA81500.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
ANA81584.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CvfB family. (299 aa)
ANA81625.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (251 aa)
rsgA-2Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (302 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (683 aa)
metG-2methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (662 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
ANA82021.130S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
asnSasparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
polCPolC-type DNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1438 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (365 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (706 aa)
ANA78688.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
ANA78820.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (816 aa)
ANA83322.1RNA-binding transcriptional accessory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (730 aa)
ANA79261.1DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ANA79551.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (368 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (71 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (139 aa)
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (670 aa)
ANA79771.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
ANA80148.1Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (165 aa)
ANA82650.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (503 aa)
ANA80233.1RNA-binding protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (442 aa)
ANA80310.1Glycerol-3-phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (374 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (891 aa)
ANA80463.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
ANA80647.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
Your Current Organism:
Paenibacillus glucanolyticus
NCBI taxonomy Id: 59843
Other names: ATCC 49278, Bacillus glucanolyticus, CCUG 28523, CIP 106935, DSM 5162, HSCC 171, IFO 15330, LMG 12239, LMG:12239, NBRC 15330, NCIMB 12809, NRRL B-14679, P. glucanolyticus
Server load: low (22%) [HD]