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mqnC mqnC ribH ribH kdsA kdsA NAMH_1686 NAMH_1686 NAMH_1577 NAMH_1577 NAMH_1476 NAMH_1476 NAMH_1412 NAMH_1412 miaA miaA NAMH_1410 NAMH_1410 NAMH_1333 NAMH_1333 mqnE mqnE NAMH_1211 NAMH_1211 uppS uppS aroA aroA NAMH_0034 NAMH_0034 ribE ribE NAMH_0050 NAMH_0050 NAMH_0074 NAMH_0074 nadA nadA metK metK cmoB cmoB hemC hemC NAMH_0828 NAMH_0828 NAMH_0889 NAMH_0889 murA murA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
mqnCConserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (348 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM TIGR01362; Belongs to the KdsA family. (261 aa)
NAMH_1686Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (281 aa)
NAMH_1577Cysteine synthase (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase); Identified by match to protein family HMM PF00291. (272 aa)
NAMH_1476Thiamine monophosphate synthase; Identified by match to protein family HMM PF02581. (173 aa)
NAMH_14123-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358. (453 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (284 aa)
NAMH_1410Putative 4-hydroxybenzoate polyprenyltransferase; Identified by match to protein family HMM PF01040; match to protein family HMM TIGR01475; Belongs to the UbiA prenyltransferase family. (279 aa)
NAMH_1333Putative Galanin. (312 aa)
mqnEConserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (354 aa)
NAMH_1211Dihydropteroate synthase; Identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496. (386 aa)
uppSUndecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (220 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa)
NAMH_0034Conserved hypothetical protein. (166 aa)
ribERiboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187. (201 aa)
NAMH_0050Thiamine monophosphate synthase; Identified by match to protein family HMM PF02581. (231 aa)
NAMH_0074Thiamine-phosphate pyrophosphorylase. (132 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (323 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (382 aa)
cmoBGeneric methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. (300 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (291 aa)
NAMH_0828Flavoprotein; Identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421. (171 aa)
NAMH_0889O-acetylhomoserine sulfhydrylase: MetY; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326. (420 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)
Your Current Organism:
Nautilia profundicola
NCBI taxonomy Id: 598659
Other names: N. profundicola AmH, Nautilia profundicola AmH, Nautilia profundicola str. AmH, Nautilia profundicola strain AmH, Nautilia sp. AmH, epsilon proteobacterium AmH
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