node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ2 | DHDDS | ENSFALP00000005420 | ENSFALP00000000380 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.873 |
COQ2 | FBXO30 | ENSFALP00000005420 | ENSFALP00000013629 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | F-box protein 30. | 0.730 |
COQ2 | GGPS1 | ENSFALP00000005420 | ENSFALP00000014134 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.736 |
COQ2 | HMGCR | ENSFALP00000005420 | ENSFALP00000010514 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.689 |
COQ2 | IDI1 | ENSFALP00000005420 | ENSFALP00000007292 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.940 |
COQ2 | MVD | ENSFALP00000005420 | ENSFALP00000003642 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.457 |
COQ2 | MVK | ENSFALP00000005420 | ENSFALP00000009108 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.597 |
COQ2 | NUS1 | ENSFALP00000005420 | ENSFALP00000011637 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.873 |
COQ2 | PDSS1 | ENSFALP00000005420 | ENSFALP00000007513 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. | 0.962 |
COQ2 | PDSS2 | ENSFALP00000005420 | ENSFALP00000012216 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. | 0.962 |
DHDDS | COQ2 | ENSFALP00000000380 | ENSFALP00000005420 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.873 |
DHDDS | FBXO30 | ENSFALP00000000380 | ENSFALP00000013629 | Alkyl transferase; Belongs to the UPP synthase family. | F-box protein 30. | 0.759 |
DHDDS | FNTB | ENSFALP00000000380 | ENSFALP00000001251 | Alkyl transferase; Belongs to the UPP synthase family. | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | 0.942 |
DHDDS | GGPS1 | ENSFALP00000000380 | ENSFALP00000014134 | Alkyl transferase; Belongs to the UPP synthase family. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.961 |
DHDDS | HMGCR | ENSFALP00000000380 | ENSFALP00000010514 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.541 |
DHDDS | IDI1 | ENSFALP00000000380 | ENSFALP00000007292 | Alkyl transferase; Belongs to the UPP synthase family. | Nudix hydrolase domain-containing protein. | 0.874 |
DHDDS | MVD | ENSFALP00000000380 | ENSFALP00000003642 | Alkyl transferase; Belongs to the UPP synthase family. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.502 |
DHDDS | MVK | ENSFALP00000000380 | ENSFALP00000009108 | Alkyl transferase; Belongs to the UPP synthase family. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.510 |
DHDDS | NUS1 | ENSFALP00000000380 | ENSFALP00000011637 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.998 |
DHDDS | PDSS1 | ENSFALP00000000380 | ENSFALP00000007513 | Alkyl transferase; Belongs to the UPP synthase family. | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. | 0.956 |