STRINGSTRING
DBNL DBNL CNKSR1 CNKSR1 MYO1A MYO1A RIMS3 RIMS3 RHOC RHOC RND2 RND2 INSC INSC SEPT9 SEPT9 ANKRD24 ANKRD24 U3JDW4_FICAL U3JDW4_FICAL EXOC7 EXOC7 CLTA CLTA LLGL2 LLGL2 HAX1 HAX1 GLRX3 GLRX3 SPTB SPTB CDK5RAP2 CDK5RAP2 EPB41 EPB41 SPTAN1 SPTAN1 FNBP1 FNBP1 TSC1 TSC1 SEPTIN6 SEPTIN6 RHOBTB2 RHOBTB2 U3JH65_FICAL U3JH65_FICAL RAI14 RAI14 FNBP1L FNBP1L ADD3 ADD3 MYO6 MYO6 C2CD5 C2CD5 GPSM2 GPSM2 DYNC1H1 DYNC1H1 SEPTIN7 SEPTIN7 EXOC3L4 EXOC3L4 TNFAIP2 TNFAIP2 ANLN ANLN U3JJH1_FICAL U3JJH1_FICAL GNAI3 GNAI3 SPIRE2 SPIRE2 CYTIP CYTIP FRYL FRYL CDH15 CDH15 EXOC8 EXOC8 ARV1 ARV1 U3JL77_FICAL U3JL77_FICAL PJVK PJVK SEPTIN2 SEPTIN2 SEPTIN10 SEPTIN10 CRIP2 CRIP2 EXOC1L EXOC1L EXOC1 EXOC1 EXOC5 EXOC5 U3JMA2_FICAL U3JMA2_FICAL PARD3B PARD3B SLC2A1 SLC2A1 SPTBN4 SPTBN4 ERC1 ERC1 AXIN1 AXIN1 MYO1B MYO1B LOC101811337 LOC101811337 SEPTIN12 SEPTIN12 LOC101822000 LOC101822000 PAFAH1B1 PAFAH1B1 PARD6G PARD6G SAPCD2 SAPCD2 CTBP2 CTBP2 EXOC3 EXOC3 NOS2 NOS2 ARHGAP32 ARHGAP32 ACTN1 ACTN1 CLASP2 CLASP2 PKD2 PKD2 MAPRE1 MAPRE1 PSEN1 PSEN1 ASPH ASPH NSMF NSMF STXBP6 STXBP6 U3JTQ4_FICAL U3JTQ4_FICAL U3JTR0_FICAL U3JTR0_FICAL SPTBN5 SPTBN5 RIMS2 RIMS2 CDH2 CDH2 NUMA1 NUMA1 PHLDB2 PHLDB2 FLOT2 FLOT2 SPIRE1 SPIRE1 KDF1 KDF1 COTL1 COTL1 LOC101812659 LOC101812659 PARD6A PARD6A RIMS1 RIMS1 VCL VCL NF2 NF2 EXOC3L1 EXOC3L1 PARD3 PARD3 MTSS2 MTSS2 MYO10 MYO10 COBL COBL U3JYK7_FICAL U3JYK7_FICAL EXOC6 EXOC6 LOC101816078 LOC101816078 SEPTIN5 SEPTIN5 U3K028_FICAL U3K028_FICAL U3K031_FICAL U3K031_FICAL DCTN4 DCTN4 ECT2 ECT2 FRY FRY SEPTIN11 SEPTIN11 ERC2 ERC2 CLTB CLTB PDLIM7 PDLIM7 DBN1 DBN1 RHOA RHOA GNAI2 GNAI2 U3K2K1_FICAL U3K2K1_FICAL U3K2Q8_FICAL U3K2Q8_FICAL NDFIP1 NDFIP1 FGF1 FGF1 RHOF RHOF HIP1R HIP1R WDR1 WDR1 CALD1 CALD1 UNC13B UNC13B C2CD2L C2CD2L PHLDB1 PHLDB1 AQP7 AQP7 MAEA MAEA CTTNBP2 CTTNBP2 CTBP1 CTBP1 CAPZA2 CAPZA2 CAV1 CAV1 STIM1 STIM1 PPP1R9A PPP1R9A AKAP13 AKAP13 GNAI1 GNAI1 GOLGB1 GOLGB1 LOC101805706 LOC101805706 CAPZB CAPZB CIB2 CIB2 CTSZ CTSZ LOC101816873 LOC101816873 NRBP1 NRBP1 U3K9T4_FICAL U3K9T4_FICAL U3K9U4_FICAL U3K9U4_FICAL SPTBN1 SPTBN1 U3KAF8_FICAL U3KAF8_FICAL U3KAH2_FICAL U3KAH2_FICAL PSEN2 PSEN2 MPP1 MPP1 EPB41L2 EPB41L2 RAC3 RAC3 SEPTIN3 SEPTIN3 U3KBE9_FICAL U3KBE9_FICAL RHOBTB3 RHOBTB3 EXOC4 EXOC4 MKLN1 MKLN1 U3KBS2_FICAL U3KBS2_FICAL UNC13C UNC13C CTNNB1 CTNNB1 U3KCV0_FICAL U3KCV0_FICAL RHOD RHOD TRAF6 TRAF6 ITCH ITCH EZR EZR PLEKHH2 PLEKHH2 MLPH MLPH RAC2 RAC2 MELK MELK STOX1 STOX1 PARD6B PARD6B EXOC2 EXOC2 CLASP1 CLASP1 U3KFN0_FICAL U3KFN0_FICAL RHOBTB1 RHOBTB1 RIC8B RIC8B SEPTIN8 SEPTIN8 U3KGA2_FICAL U3KGA2_FICAL CAV3 CAV3 ACTR2 ACTR2 BFSP1 BFSP1 LLGL1 LLGL1 SEPT4 SEPT4 MYO9B MYO9B RND3 RND3 MISP MISP RAC1 RAC1 SHROOM1 SHROOM1 BASP1 BASP1 ARF6 ARF6 ERMN ERMN CLDN5 CLDN5 U3KJM0_FICAL U3KJM0_FICAL RHOG RHOG RHOG-2 RHOG-2 RHOB RHOB ARC ARC RHOH RHOH LOC101809398 LOC101809398
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DBNLDrebrin like. (413 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (864 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1077 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (309 aa)
RHOCUncharacterized protein. (197 aa)
RND2Rho family GTPase 2. (195 aa)
INSCINSC spindle orientation adaptor protein. (487 aa)
SEPT9Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (584 aa)
ANKRD24ANK_REP_REGION domain-containing protein. (505 aa)
U3JDW4_FICALUncharacterized protein. (86 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (781 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (210 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1027 aa)
HAX1Uncharacterized protein. (111 aa)
GLRX3Glutaredoxin 3. (328 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2226 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1874 aa)
EPB41Erythrocyte membrane protein band 4.1. (866 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2510 aa)
FNBP1Formin binding protein 1. (617 aa)
TSC1TSC complex subunit 1. (1153 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (496 aa)
RHOBTB2Rho related BTB domain containing 2. (754 aa)
U3JH65_FICALUncharacterized protein. (1312 aa)
RAI14Retinoic acid induced 14. (974 aa)
FNBP1LFormin binding protein 1 like. (532 aa)
ADD3Adducin 3. (708 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1299 aa)
C2CD5C2 calcium dependent domain containing 5. (1134 aa)
GPSM2G protein signaling modulator 2. (662 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4467 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (391 aa)
EXOC3L4Exocyst complex component 3 like 4. (700 aa)
TNFAIP2TNF alpha induced protein 2. (691 aa)
ANLNAnillin actin binding protein. (1098 aa)
U3JJH1_FICALUncharacterized protein. (250 aa)
GNAI3G protein subunit alpha i3. (354 aa)
SPIRE2Spire type actin nucleation factor 2. (639 aa)
CYTIPPDZ domain-containing protein. (137 aa)
FRYLFRY like transcription coactivator. (3104 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (672 aa)
EXOC8Exocyst complex component 8. (687 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (201 aa)
U3JL77_FICALUncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (426 aa)
PJVKGasdermin domain-containing protein. (357 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (362 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (450 aa)
CRIP2Cysteine rich protein 2. (208 aa)
EXOC1LExocyst complex component 1 like. (121 aa)
EXOC1Exocyst complex component 1. (920 aa)
EXOC5Exocyst complex component 5. (709 aa)
U3JMA2_FICALUncharacterized protein. (56 aa)
PARD3BUncharacterized protein. (997 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (483 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2401 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1118 aa)
AXIN1Axin 1. (846 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
LOC101811337Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2040 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
LOC101822000Uncharacterized protein. (288 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
PARD6GPar-6 family cell polarity regulator gamma. (361 aa)
SAPCD2Suppressor APC domain containing 2. (399 aa)
CTBP2C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
EXOC3Exocyst complex component 3. (745 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1147 aa)
ARHGAP32Rho GTPase activating protein 32. (1633 aa)
ACTN1Actinin alpha 1. (849 aa)
CLASP2Uncharacterized protein. (1523 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (821 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (263 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ASPHAspartate beta-hydroxylase. (776 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (500 aa)
STXBP6Syntaxin binding protein 6. (210 aa)
U3JTQ4_FICALKIND domain-containing protein. (342 aa)
U3JTR0_FICALUncharacterized protein. (129 aa)
SPTBN5Uncharacterized protein. (3883 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1570 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
NUMA1Nuclear mitotic apparatus protein 1. (1622 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1254 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (432 aa)
SPIRE1Spire type actin nucleation factor 1. (688 aa)
KDF1Keratinocyte differentiation factor 1. (357 aa)
COTL1Coactosin like F-actin binding protein 1. (142 aa)
LOC101812659FERM domain-containing protein. (664 aa)
PARD6APar-6 family cell polarity regulator alpha. (327 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1111 aa)
VCLVinculin. (1168 aa)
NF2Neurofibromin 2. (558 aa)
EXOC3L1Exocyst complex component 3 like 1. (716 aa)
PARD3Par-3 family cell polarity regulator. (1277 aa)
MTSS2MTSS I-BAR domain containing 2. (743 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2049 aa)
COBLUncharacterized protein. (817 aa)
U3JYK7_FICALCobl domain-containing protein. (348 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (808 aa)
LOC101816078Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (349 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (369 aa)
U3K028_FICALPDZ domain-containing protein. (253 aa)
U3K031_FICALDUF4685 domain-containing protein. (64 aa)
DCTN4Dynactin subunit 4. (467 aa)
ECT2Epithelial cell transforming 2. (986 aa)
FRYFRY microtubule binding protein. (3012 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (444 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (968 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (259 aa)
PDLIM7PDZ and LIM domain 7. (721 aa)
DBN1Drebrin 1. (621 aa)
RHOARas homolog family member A. (172 aa)
GNAI2G protein subunit alpha i2. (355 aa)
U3K2K1_FICALUncharacterized protein. (620 aa)
U3K2Q8_FICALCAP-Gly domain-containing protein. (1236 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
RHOFRas homolog family member F, filopodia associated. (215 aa)
HIP1RHuntingtin interacting protein 1 related. (1057 aa)
WDR1WD repeat domain 1. (610 aa)
CALD1Caldesmon 1. (748 aa)
UNC13BUnc-13 homolog B. (1613 aa)
C2CD2LC2CD2 like. (640 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1374 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (297 aa)
MAEAMacrophage erythroblast attacher. (435 aa)
CTTNBP2Cortactin binding protein 2. (1631 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
STIM1Stromal interaction molecule 1. (607 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1343 aa)
AKAP13A-kinase anchoring protein 13. (2772 aa)
GNAI1G protein subunit alpha i1. (354 aa)
GOLGB1Golgin B1. (3145 aa)
LOC101805706SH3 domain-containing protein. (497 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (277 aa)
CIB2Uncharacterized protein. (187 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (304 aa)
LOC101816873Uncharacterized protein. (143 aa)
NRBP1Nuclear receptor binding protein 1. (455 aa)
U3K9T4_FICALUncharacterized protein. (194 aa)
U3K9U4_FICALSec3_C domain-containing protein. (808 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2359 aa)
U3KAF8_FICALUncharacterized protein. (1737 aa)
U3KAH2_FICALRho-GAP domain-containing protein. (324 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
MPP1Membrane palmitoylated protein 1; Belongs to the MAGUK family. (433 aa)
EPB41L2Erythrocyte membrane protein band 4.1 like 2. (1006 aa)
RAC3Rac family small GTPase 3. (180 aa)
SEPTIN3Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (350 aa)
U3KBE9_FICALUncharacterized protein. (480 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
EXOC4Uncharacterized protein. (179 aa)
MKLN1Muskelin 1. (769 aa)
U3KBS2_FICALC2 domain-containing protein. (160 aa)
UNC13CUnc-13 homolog C. (2207 aa)
CTNNB1Catenin beta 1. (781 aa)
U3KCV0_FICALRab_eff_C domain-containing protein. (686 aa)
RHODRas homolog family member D. (209 aa)
TRAF6TNF receptor-associated factor. (471 aa)
ITCHE3 ubiquitin-protein ligase. (878 aa)
EZREzrin. (648 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1512 aa)
MLPHMelanophilin. (680 aa)
RAC2Rac family small GTPase 2. (192 aa)
MELKNon-specific serine/threonine protein kinase. (617 aa)
STOX1Stork_head domain-containing protein. (298 aa)
PARD6BPar-6 family cell polarity regulator beta. (371 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (925 aa)
CLASP1Cytoplasmic linker associated protein 1. (1567 aa)
U3KFN0_FICALDH domain-containing protein. (553 aa)
RHOBTB1Rho related BTB domain containing 1. (694 aa)
RIC8BRIC8 guanine nucleotide exchange factor B. (550 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
U3KGA2_FICALASD2 domain-containing protein. (173 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (378 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (660 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1025 aa)
SEPT4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (464 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2047 aa)
RND3Rho family GTPase 3. (244 aa)
MISPAKAP2_C domain-containing protein. (771 aa)
RAC1Rac family small GTPase 1. (192 aa)
SHROOM1ASD1 domain-containing protein. (345 aa)
BASP1Brain abundant membrane attached signal protein 1. (243 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ERMNUncharacterized protein. (89 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
U3KJM0_FICALFlotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (50 aa)
RHOGUncharacterized protein. (191 aa)
RHOG-2Ras homolog family member G. (191 aa)
RHOBRas homolog family member B. (196 aa)
ARCActivity regulated cytoskeleton associated protein. (404 aa)
RHOHRas homolog family member H. (191 aa)
LOC101809398Uncharacterized protein. (191 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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