STRINGSTRING
CFTR CFTR U3JB88_FICAL U3JB88_FICAL GMCL1 GMCL1 TTC12 TTC12 CEP57 CEP57 PAQR7 PAQR7 ATM ATM ZPBP2 ZPBP2 PITHD1 PITHD1 KLHL10 KLHL10 WDR77 WDR77 DDX20 DDX20 U3JEB1_FICAL U3JEB1_FICAL U3JEG7_FICAL U3JEG7_FICAL TDRD7 TDRD7 SYCP1 SYCP1 NAIF1 NAIF1 TDRD6 TDRD6 CFAP47 CFAP47 U3JFY3_FICAL U3JFY3_FICAL U3JFY8_FICAL U3JFY8_FICAL U3JFZ1_FICAL U3JFZ1_FICAL TDRD15 TDRD15 MEIG1 MEIG1 SPEF2 SPEF2 NANOS1 NANOS1 RSPH1 RSPH1 TDRD1 TDRD1 U3JIX9_FICAL U3JIX9_FICAL MEI4 MEI4 LOC101813094 LOC101813094 MLH1 MLH1 CFAP206 CFAP206 UBE2J1 UBE2J1 ACVR1 ACVR1 FBXW11 FBXW11 C14orf39 C14orf39 FANCC FANCC KIT KIT TUT7 TUT7 U3JMF5_FICAL U3JMF5_FICAL OCA2 OCA2 U3JNB8_FICAL U3JNB8_FICAL CFAP65 CFAP65 IHH IHH U3JP23_FICAL U3JP23_FICAL ZNF830 ZNF830 PAFAH1B1 PAFAH1B1 PTX3 PTX3 ACRBP ACRBP SPAG17 SPAG17 DDX25 DDX25 TMEM53 TMEM53 EDNRA EDNRA BCL2L1 BCL2L1 JAM3 JAM3 TUT4 TUT4 TBC1D20 TBC1D20 U3JT75_FICAL U3JT75_FICAL VPS13B VPS13B LOC101805674 LOC101805674 U3JTS6_FICAL U3JTS6_FICAL CFAP44 CFAP44 LOC101811636 LOC101811636 U3JUH2_FICAL U3JUH2_FICAL SELENOF SELENOF NECTIN3 NECTIN3 YTHDC1 YTHDC1 MTHFSD MTHFSD TTLL1 TTLL1 TDRKH TDRKH DRC7 DRC7 AGFG1 AGFG1 SPAG6 SPAG6 BBS2 BBS2 IQCG IQCG MEIOC MEIOC NME5 NME5 CFAP69 CFAP69 ROPN1L ROPN1L RBP4 RBP4 U3K0B4_FICAL U3K0B4_FICAL EREG EREG TDRD5 TDRD5 ADAD1 ADAD1 SLC26A6 SLC26A6 PRDM14 PRDM14 FNDC3A FNDC3A BRCA2 BRCA2 SOX30 SOX30 U3K1I5_FICAL U3K1I5_FICAL STAU2 STAU2 NEURL1 NEURL1 CFAP43 CFAP43 CFAP58 CFAP58 DAZL DAZL GDF9 GDF9 AFF4 AFF4 SYCP3 SYCP3 IFT81 IFT81 PACRGL PACRGL PIWIL1 PIWIL1 DND1 DND1 BBS4 BBS4 FANCG FANCG ZBTB16 ZBTB16 HEXB HEXB SLC26A3 SLC26A3 MTOR MTOR LGR5 LGR5 DMRT1 DMRT1 ABHD2 ABHD2 PCK1 PCK1 SPO11 SPO11 PIWIL2 PIWIL2 MKKS MKKS CIB1 CIB1 MSH2 MSH2 U3K9E3_FICAL U3K9E3_FICAL RNF8 RNF8 STRA8 STRA8 PSME4 PSME4 HMGB2 HMGB2 TTC26 TTC26 PRDM1 PRDM1 ARMC2 ARMC2 CEP57L1 CEP57L1 TBPL1 TBPL1 JAM2 JAM2 PYGO1 PYGO1 PACRG PACRG QKI QKI CTNNB1 CTNNB1 ZP3 ZP3 RPS6KA2 RPS6KA2 CCR6 CCR6 FBXO5 FBXO5 DMC1 DMC1 CEP131 CEP131 RSPH3 RSPH3 STAU1 STAU1 U3KEQ3_FICAL U3KEQ3_FICAL SPAG16 SPAG16 BCL2 BCL2 CCDC36 CCDC36 CDYL CDYL INHBB INHBB TRIP13 TRIP13 TMF1 TMF1 EDN1 EDN1 CFAP221 CFAP221 PLD6 PLD6 TNFAIP6 TNFAIP6 PDILT PDILT MARF1 MARF1 TPGS1 TPGS1 DMRTB1 DMRTB1 ING2 ING2 PAQR5 PAQR5 PAQR8 PAQR8 PYGO2 PYGO2 TSSK6 TSSK6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1403 aa)
U3JB88_FICALUncharacterized protein. (1365 aa)
GMCL1BTB domain-containing protein. (456 aa)
TTC12TPR_REGION domain-containing protein. (775 aa)
CEP57Centrosomal protein 57. (504 aa)
PAQR7Progestin and adipoQ receptor family member 7. (343 aa)
ATMNon-specific serine/threonine protein kinase. (3066 aa)
ZPBP2Zona pellucida binding protein 2. (349 aa)
PITHD1PITH domain containing 1. (204 aa)
KLHL10Kelch like family member 10. (590 aa)
WDR77WD repeat domain 77. (259 aa)
DDX20DEAD-box helicase 20; Belongs to the DEAD box helicase family. (700 aa)
U3JEB1_FICALUncharacterized protein. (387 aa)
U3JEG7_FICALUncharacterized protein. (491 aa)
TDRD7Tudor domain containing 7. (1056 aa)
SYCP1Synaptonemal complex protein 1. (993 aa)
NAIF1Nuclear apoptosis inducing factor 1. (320 aa)
TDRD6Tudor domain containing 6. (2311 aa)
CFAP47MSP domain-containing protein. (865 aa)
U3JFY3_FICALUncharacterized protein. (309 aa)
U3JFY8_FICALUncharacterized protein. (112 aa)
U3JFZ1_FICALUncharacterized protein. (356 aa)
TDRD15Tudor domain containing 15. (1094 aa)
MEIG1Meiosis/spermiogenesis associated 1. (95 aa)
SPEF2Sperm flagellar 2. (1681 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (281 aa)
RSPH1Radial spoke head component 1. (267 aa)
TDRD1Tudor domain containing 1. (732 aa)
U3JIX9_FICALUncharacterized protein. (1309 aa)
MEI4Meiotic double-stranded break formation protein 4. (370 aa)
LOC101813094Uncharacterized protein. (766 aa)
MLH1MutL homolog 1. (717 aa)
CFAP206Uncharacterized protein. (621 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (315 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
FBXW11F-box and WD repeat domain containing 11. (531 aa)
C14orf39Uncharacterized protein. (493 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (566 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
TUT7Terminal uridylyl transferase 7. (1483 aa)
U3JMF5_FICALUncharacterized protein. (114 aa)
OCA2OCA2 melanosomal transmembrane protein. (752 aa)
U3JNB8_FICALUncharacterized protein. (1034 aa)
CFAP65Cilia and flagella associated protein 65. (1763 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
U3JP23_FICALKH_dom_type_1 domain-containing protein. (122 aa)
ZNF830Zinc finger protein 830. (289 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
PTX3Pentraxin 3. (426 aa)
ACRBPAcrosin binding protein. (545 aa)
SPAG17Sperm associated antigen 17. (2137 aa)
DDX25DEAD-box helicase 25. (418 aa)
TMEM53Transmembrane protein 53. (308 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
BCL2L1BCL2 like 1. (230 aa)
JAM3Junctional adhesion molecule 3. (298 aa)
TUT4Terminal uridylyl transferase 4. (1626 aa)
TBC1D20TBC1 domain family member 20. (384 aa)
U3JT75_FICALChorein_N domain-containing protein. (196 aa)
VPS13BUncharacterized protein. (3900 aa)
LOC101805674DMRT like family B with proline rich C-terminal 1. (274 aa)
U3JTS6_FICALUncharacterized protein. (885 aa)
CFAP44Cilia and flagella associated protein 44. (879 aa)
LOC101811636Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (150 aa)
U3JUH2_FICALNanos-type domain-containing protein; Belongs to the nanos family. (84 aa)
SELENOFSelenoprotein F. (152 aa)
NECTIN3Nectin cell adhesion molecule 3. (496 aa)
YTHDC1YTH domain containing 1. (500 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (401 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
TDRKHTudor domain-containing protein. (216 aa)
DRC7Dynein regulatory complex subunit 7. (738 aa)
AGFG1ArfGAP with FG repeats 1. (534 aa)
SPAG6Sperm associated antigen 6. (434 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (683 aa)
IQCGIQ motif containing G. (383 aa)
MEIOCMeiosis specific with coiled-coil domain. (646 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (208 aa)
CFAP69Cilia and flagella associated protein 69. (909 aa)
ROPN1LRhophilin associated tail protein 1 like. (218 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
U3K0B4_FICALUncharacterized protein. (350 aa)
EREGEpiregulin. (153 aa)
TDRD5Tudor domain containing 5. (726 aa)
ADAD1Adenosine deaminase domain containing 1. (567 aa)
SLC26A6Solute carrier family 26 member 6. (758 aa)
PRDM14PR/SET domain 14. (321 aa)
FNDC3AFibronectin type III domain containing 3A. (1166 aa)
BRCA2BRCA2 DNA repair associated. (3362 aa)
SOX30SRY-box transcription factor 30. (486 aa)
U3K1I5_FICALKazal-like domain-containing protein. (72 aa)
STAU2Staufen double-stranded RNA binding protein 2. (680 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (555 aa)
CFAP43Cilia and flagella associated protein 43. (1683 aa)
CFAP58Cilia and flagella associated protein 58. (846 aa)
DAZLRRM domain-containing protein. (244 aa)
GDF9Growth differentiation factor 9. (451 aa)
AFF4AF4/FMR2 family member 4. (1170 aa)
SYCP3Cor1 domain-containing protein. (238 aa)
IFT81Intraflagellar transport 81. (676 aa)
PACRGLParkin coregulated like. (222 aa)
PIWIL1Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (762 aa)
DND1DND microRNA-mediated repression inhibitor 1. (351 aa)
BBS4Bardet-Biedl syndrome 4. (538 aa)
FANCGFA complementation group G. (604 aa)
ZBTB16Zinc finger and BTB domain containing 16. (674 aa)
HEXBBeta-hexosaminidase. (516 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (755 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2523 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (834 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (182 aa)
ABHD2Abhydrolase domain containing 2. (426 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (386 aa)
PIWIL2Piwi domain-containing protein. (247 aa)
MKKSMcKusick-Kaufman syndrome. (572 aa)
CIB1Calcium and integrin binding 1. (227 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (851 aa)
U3K9E3_FICALZP domain-containing protein. (474 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (470 aa)
STRA8Stimulated by retinoic acid 8. (263 aa)
PSME4Proteasome activator subunit 4. (1820 aa)
HMGB2High mobility group box 2. (208 aa)
TTC26Tetratricopeptide repeat domain 26. (554 aa)
PRDM1PR/SET domain 1. (858 aa)
ARMC2Armadillo repeat containing 2. (859 aa)
CEP57L1Centrosomal protein 57 like 1. (231 aa)
TBPL1TATA-box binding protein like 1. (183 aa)
JAM2Junctional adhesion molecule 2. (315 aa)
PYGO1Pygopus family PHD finger 1. (402 aa)
PACRGParkin coregulated. (216 aa)
QKIQKI, KH domain containing RNA binding. (302 aa)
CTNNB1Catenin beta 1. (781 aa)
ZP3ZP domain-containing protein. (419 aa)
RPS6KA2Non-specific serine/threonine protein kinase. (664 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (384 aa)
FBXO5F-box protein 5. (424 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa)
CEP131Centrosomal protein 131. (919 aa)
RSPH3Radial spoke head 3. (374 aa)
STAU1Staufen double-stranded RNA binding protein 1. (690 aa)
U3KEQ3_FICALWD_REPEATS_REGION domain-containing protein. (327 aa)
SPAG16Uncharacterized protein. (289 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CCDC36Uncharacterized protein. (127 aa)
CDYLChromo domain-containing protein. (544 aa)
INHBBInhibin subunit beta B. (320 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (457 aa)
TMF1TATA element modulatory factor 1. (1106 aa)
EDN1Endothelin 1. (209 aa)
CFAP221Cilia and flagella associated protein 221. (856 aa)
PLD6Phospholipase D family member 6. (158 aa)
TNFAIP6TNF alpha induced protein 6. (271 aa)
PDILTProtein disulfide isomerase like, testis expressed. (495 aa)
MARF1Meiosis regulator and mRNA stability factor 1. (1658 aa)
TPGS1Tubulin polyglutamylase complex subunit 1. (161 aa)
DMRTB1DM domain-containing protein. (123 aa)
ING2Inhibitor of growth protein. (233 aa)
PAQR5Uncharacterized protein. (33 aa)
PAQR8Progestin and adipoQ receptor family member 8. (353 aa)
PYGO2Pygopus family PHD finger 2. (408 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (269 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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