67 items (Ficedula albicollis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POPDC3	Popeye domain containing 3. (288 aa)
	U3KL44_FICAL	Tafazzin family protein; Belongs to the taffazin family. (30 aa)
	U3KIX2_FICAL	Uncharacterized protein. (55 aa)
	ELN	Elastin. (682 aa)
	R3HDM1	R3H domain containing 1. (1166 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (615 aa)
	SOX8	SRY-box transcription factor 8. (433 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	MEF2D	Myocyte enhancer factor 2D. (493 aa)
	GPCPD1	Glycerophosphocholine phosphodiesterase 1. (678 aa)
	CDK5	Cyclin dependent kinase 5. (213 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	ATF3	Activating transcription factor 3. (198 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	U3KCH5_FICAL	Homeobox domain-containing protein. (130 aa)
	HLX	H2.0 like homeobox. (175 aa)
	EP300	E1A binding protein p300. (2447 aa)
	TCF21	Transcription factor 21. (179 aa)
	BVES	Blood vessel epicardial substance. (359 aa)
	BTG2	BTG anti-proliferation factor 2. (124 aa)
	COPS2	COP9 signalosome subunit 2. (369 aa)
	U3K9R1_FICAL	Uncharacterized protein. (384 aa)
	FOXN2	Forkhead box N2. (437 aa)
	MYF5	Myogenic factor. (258 aa)
	MYF6	Myogenic factor 6. (242 aa)
	SMYD1	SET and MYND domain containing 1. (491 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (114 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	MEOX2	Mesenchyme homeobox 2. (244 aa)
	HOMER1	Homer scaffold protein 1. (355 aa)
	EOMES	Eomesodermin. (440 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (555 aa)
	RB1	RB transcriptional corepressor 1. (924 aa)
	ANKRD33B	Ankyrin repeat domain 33B. (510 aa)
	ANKRD1	Ankyrin repeat domain 1. (341 aa)
	SVIL	Supervillin. (2112 aa)
	MYOZ1	Myozenin 1. (302 aa)
	DNER	Delta/notch like EGF repeat containing. (647 aa)
	U3JWM1_FICAL	Uncharacterized protein. (339 aa)
	PITX2	Homeobox protein. (334 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (371 aa)
	POPDC2	Popeye domain containing 2. (349 aa)
	SPG11	SPG11 vesicle trafficking associated, spatacsin. (2361 aa)
	BARX2	BARX homeobox 2. (246 aa)
	VRK3	VRK serine/threonine kinase 3. (278 aa)
	RIPOR2	PL48 domain-containing protein. (964 aa)
	KEL	Uncharacterized protein. (718 aa)
	MSTN	Myostatin. (375 aa)
	LEMD2	LEM domain containing 2. (300 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (583 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (727 aa)
	HOXD10	Homeobox D10. (339 aa)
	PHOX2B	Paired like homeobox 2B. (149 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (664 aa)
	MYOG	Myogenin. (221 aa)
	VAX1	Ventral anterior homeobox 1. (143 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (687 aa)
	MEGF10	Multiple EGF like domains 10. (1130 aa)
	HIVEP3	Human immunodeficiency virus type I enhancer binding protein 3. (1903 aa)
	KLHL40	Kelch like family member 40. (659 aa)
	KLF5	Kruppel like factor 5. (416 aa)
	MYOZ2	Myozenin 2. (263 aa)
	MYOD1	Myogenic factor. (261 aa)
	U3JCD3_FICAL	EF-hand domain-containing protein. (527 aa)
	R3HDM2	Uncharacterized protein. (889 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (587 aa)
	ANKRD33	Ankyrin repeat domain 33. (414 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD1	ASB2	ENSFALP00000008064	ENSFALP00000002587	Ankyrin repeat domain 1.	Ankyrin repeat and SOCS box containing 2.	0.440
ANKRD33	ASB2	ENSFALP00000000096	ENSFALP00000002587	Ankyrin repeat domain 33.	Ankyrin repeat and SOCS box containing 2.	0.411
ASB2	ANKRD1	ENSFALP00000002587	ENSFALP00000008064	Ankyrin repeat and SOCS box containing 2.	Ankyrin repeat domain 1.	0.440
ASB2	ANKRD33	ENSFALP00000002587	ENSFALP00000000096	Ankyrin repeat and SOCS box containing 2.	Ankyrin repeat domain 33.	0.411
ATF3	FOS	ENSFALP00000012954	ENSFALP00000006629	Activating transcription factor 3.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.787
ATF3	NR4A1	ENSFALP00000012954	ENSFALP00000000104	Activating transcription factor 3.	Nuclear receptor subfamily 4 group A member 1.	0.443
BCL2	NR4A1	ENSFALP00000013568	ENSFALP00000000104	BCL2 apoptosis regulator.	Nuclear receptor subfamily 4 group A member 1.	0.765
BTG2	NR4A1	ENSFALP00000012071	ENSFALP00000000104	BTG anti-proliferation factor 2.	Nuclear receptor subfamily 4 group A member 1.	0.458
CAV1	CAV2	ENSFALP00000010549	ENSFALP00000010554	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.995
CAV1	CAV3	ENSFALP00000010549	ENSFALP00000014211	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.960
CAV2	CAV1	ENSFALP00000010554	ENSFALP00000010549	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.995
CAV2	CAV3	ENSFALP00000010554	ENSFALP00000014211	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.995
CAV3	CAV1	ENSFALP00000014211	ENSFALP00000010549	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.960
CAV3	CAV2	ENSFALP00000014211	ENSFALP00000010554	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.995
CCNT2	CDK5	ENSFALP00000014323	ENSFALP00000013642	Cyclin T2; Belongs to the cyclin family.	Cyclin dependent kinase 5.	0.459
CDK5	CCNT2	ENSFALP00000013642	ENSFALP00000014323	Cyclin dependent kinase 5.	Cyclin T2; Belongs to the cyclin family.	0.459
EGR1	EP300	ENSFALP00000003551	ENSFALP00000012569	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	E1A binding protein p300.	0.414
EGR1	FOS	ENSFALP00000003551	ENSFALP00000006629	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.804
EP300	EGR1	ENSFALP00000012569	ENSFALP00000003551	E1A binding protein p300.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.414
EP300	FOS	ENSFALP00000012569	ENSFALP00000006629	E1A binding protein p300.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.751