STRINGSTRING
PIGH PIGH INPP4B INPP4B PIGQ PIGQ LPCAT3 LPCAT3 PIGA PIGA C2orf66 C2orf66 PGAP1 PGAP1 U3JNI7_FICAL U3JNI7_FICAL FAM126B FAM126B PCYT1B PCYT1B PIK3CB PIK3CB INPP4A INPP4A IP6K3 IP6K3 ATG14 ATG14 HMGCS2 HMGCS2 PIKFYVE PIKFYVE MVD MVD SOCS7 SOCS7 PLA2G4A PLA2G4A DGKG DGKG GNPAT GNPAT CWH43 CWH43 PIP5K1B PIP5K1B PIGX PIGX HDHD5 HDHD5 TMEM38B TMEM38B IMPA2 IMPA2 FAM102B FAM102B ETNK1 ETNK1 AGPAT1 AGPAT1 CEPT1 CEPT1 DGKE DGKE GPAM GPAM LPCAT1 LPCAT1 SH3YL1 SH3YL1 AGPAT2 AGPAT2 ADGRF5 ADGRF5 DPM2 DPM2 FAM102A FAM102A DGKQ DGKQ PIK3C2A PIK3C2A PGAP3 PGAP3 DGKI DGKI ETNK2 ETNK2 ATM ATM PIK3C2B PIK3C2B DHDDS DHDDS PIGV PIGV CDS2 CDS2 TAMM41 TAMM41 U3JB71_FICAL U3JB71_FICAL GPAT2 GPAT2 RUSC1 RUSC1 PIGS PIGS MBOAT2 MBOAT2 SAMD8 SAMD8 IDI1 IDI1 PIGZ PIGZ TMEM150A TMEM150A PIP4K2A PIP4K2A PIK3CD PIK3CD VAC14 VAC14 PRR14L PRR14L PISD PISD PCYT1A PCYT1A PI4KA PI4KA LPCAT2 LPCAT2 U3JZZ5_FICAL U3JZZ5_FICAL RGSL1 RGSL1 IP6K2 IP6K2 PIK3CA PIK3CA PI4K2A PI4K2A PLD1 PLD1 FABP5 FABP5 IMPA1 IMPA1 MVK MVK PIK3C3 PIK3C3 SELENOI SELENOI CISH CISH IP6K1 IP6K1 CHPT1 CHPT1 ABHD5 ABHD5 PI4K2B PI4K2B ISYNA1 ISYNA1 PIK3R3 PIK3R3 FAM126A FAM126A PIGO PIGO PIK3R1 PIK3R1 SERINC5 SERINC5 DGKB DGKB HEXB HEXB PGAP2 PGAP2 PIK3CG PIK3CG IMPAD1 IMPAD1 PLA2G2A PLA2G2A SOCS2 SOCS2 PI4KB PI4KB HMGCS1 HMGCS1 NUS1 NUS1 SERINC4 SERINC4 LCLAT1 LCLAT1 ITPKB ITPKB PTDSS2 PTDSS2 PIP5K1C PIP5K1C FIG4 FIG4 PCYT2 PCYT2 UVRAG UVRAG PIGB PIGB BPNT1 BPNT1 AGPAT4 AGPAT4 PGS1 PGS1 TTC7B TTC7B AGPAT3 AGPAT3 SGMS2 SGMS2 PIK3R4 PIK3R4 SERAC1 SERAC1 PIGU PIGU PLA2G6 PLA2G6 CHKA CHKA TTC7A TTC7A PIGF PIGF PIGN PIGN DPM1 DPM1 SGMS1 SGMS1 IPMK IPMK PIP4K2B PIP4K2B MBOAT1 MBOAT1 GGPS1 GGPS1 CRLS1 CRLS1 ABHD8 ABHD8 AGPAT1-2 AGPAT1-2 U3KH27_FICAL U3KH27_FICAL PEMT PEMT DHRS7B DHRS7B PIK3R2 PIK3R2 SMG1-2 SMG1-2 U3KI07_FICAL U3KI07_FICAL U3KID9_FICAL U3KID9_FICAL TMPPE TMPPE SOCS5 SOCS5 PIGC PIGC SOCS6 SOCS6 SOCS1 SOCS1 SOCS4 SOCS4 PIGM PIGM GPAT4 GPAT4 PIGW PIGW U3KL44_FICAL U3KL44_FICAL U3KL79_FICAL U3KL79_FICAL DOLK DOLK MPPE1 MPPE1 PTPMT1 PTPMT1 INPPL1 INPPL1 DGKZ DGKZ ITPKA ITPKA PIGL PIGL PYURF PYURF LOC101820004 LOC101820004 PIGK PIGK PTDSS1 PTDSS1 APOA1 APOA1 PIGT PIGT PIGG PIGG CDS1 CDS1 U3JRY6_FICAL U3JRY6_FICAL LOC101817598 LOC101817598 FITM2 FITM2 PIGP PIGP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIGHPhosphatidylinositol glycan anchor biosynthesis class H. (167 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (923 aa)
PIGQPhosphatidylinositol glycan anchor biosynthesis class Q. (573 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (400 aa)
PIGAPhosphatidylinositol glycan anchor biosynthesis class A. (461 aa)
C2orf66Chromosome 2 open reading frame 66. (101 aa)
PGAP1Post-GPI attachment to proteins 1. (925 aa)
U3JNI7_FICALSH2 domain-containing protein. (914 aa)
FAM126BFamily with sequence similarity 126 member B. (587 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (350 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (939 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (464 aa)
ATG14Autophagy related 14. (411 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (504 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2117 aa)
MVDDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (409 aa)
SOCS7Suppressor of cytokine signaling 7. (237 aa)
PLA2G4APhospholipase A2. (753 aa)
DGKGDiacylglycerol kinase. (875 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (660 aa)
CWH43Cell wall biogenesis 43 C-terminal homolog. (701 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (545 aa)
PIGXPhosphatidylinositol glycan anchor biosynthesis class X. (271 aa)
HDHD5Haloacid dehalogenase like hydrolase domain containing 5. (363 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
IMPA2Inositol-1-monophosphatase. (276 aa)
FAM102BFamily with sequence similarity 102 member B. (359 aa)
ETNK1Ethanolamine kinase 1. (363 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (206 aa)
CEPT1Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (414 aa)
DGKEDiacylglycerol kinase. (523 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (485 aa)
SH3YL1SH3 and SYLF domain containing 1. (307 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (272 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1348 aa)
DPM2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa)
FAM102AFamily with sequence similarity 102 member A. (381 aa)
DGKQDiacylglycerol kinase. (845 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1700 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (323 aa)
DGKIDiacylglycerol kinase. (926 aa)
ETNK2Ethanolamine kinase 2. (333 aa)
ATMNon-specific serine/threonine protein kinase. (3066 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1613 aa)
DHDDSAlkyl transferase; Belongs to the UPP synthase family. (333 aa)
PIGVGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (310 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (450 aa)
TAMM41Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (289 aa)
U3JB71_FICALUncharacterized protein. (394 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (744 aa)
RUSC1RUN and SH3 domain containing 1. (766 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (551 aa)
MBOAT2Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (496 aa)
SAMD8Sterile alpha motif domain containing 8. (411 aa)
IDI1Nudix hydrolase domain-containing protein. (227 aa)
PIGZMannosyltransferase. (556 aa)
TMEM150AUncharacterized protein. (267 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (370 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
VAC14VAC14 component of PIKFYVE complex. (779 aa)
PRR14LTantalus domain-containing protein. (462 aa)
PISDPhosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (398 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (407 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2045 aa)
LPCAT2Lysophosphatidylcholine acyltransferase 2. (540 aa)
U3JZZ5_FICALUncharacterized protein. (125 aa)
RGSL1Uncharacterized protein. (262 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (428 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PI4K2API3K/PI4K domain-containing protein. (417 aa)
PLD1Phospholipase. (1075 aa)
FABP5Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
IMPA1Inositol-1-monophosphatase. (278 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (882 aa)
SELENOISelenoprotein I; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (407 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (431 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (316 aa)
ABHD5Abhydrolase domain containing 5. (340 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (405 aa)
ISYNA1Inositol-3-phosphate synthase 1. (543 aa)
PIK3R3Uncharacterized protein. (753 aa)
FAM126AFamily with sequence similarity 126 member A. (515 aa)
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1101 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SERINC5Serine incorporator 5. (465 aa)
DGKBDiacylglycerol kinase. (814 aa)
HEXBBeta-hexosaminidase. (516 aa)
PGAP2Post-GPI attachment to proteins 2. (312 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (958 aa)
IMPAD1Inositol monophosphatase domain containing 1. (230 aa)
PLA2G2APhospholipase A(2). (140 aa)
SOCS2Suppressor of cytokine signaling 2. (196 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (731 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (220 aa)
SERINC4Serine incorporator 4. (472 aa)
LCLAT1Lysocardiolipin acyltransferase 1. (389 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (507 aa)
PTDSS2Phosphatidylserine synthase 2. (422 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (724 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (889 aa)
PCYT2Phosphate cytidylyltransferase 2, ethanolamine. (350 aa)
UVRAGUV radiation resistance associated. (586 aa)
PIGBMannosyltransferase. (456 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (307 aa)
AGPAT41-acylglycerol-3-phosphate O-acyltransferase 4. (382 aa)
PGS1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (513 aa)
TTC7BTetratricopeptide repeat domain 7B. (810 aa)
AGPAT31-acylglycerol-3-phosphate O-acyltransferase 3. (377 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1361 aa)
SERAC1Serine active site containing 1. (657 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U. (435 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
CHKACholine kinase alpha. (373 aa)
TTC7ATetratricopeptide repeat domain 7A. (742 aa)
PIGFPhosphatidylinositol glycan anchor biosynthesis class F. (219 aa)
PIGNPhosphatidylinositol glycan anchor biosynthesis class N. (842 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (242 aa)
SGMS1Sphingomyelin synthase 1. (413 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (420 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (366 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (471 aa)
GGPS1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (298 aa)
CRLS1Cardiolipin synthase 1. (200 aa)
ABHD8Abhydrolase domain containing 8. (411 aa)
AGPAT1-21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (289 aa)
U3KH27_FICAL1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (286 aa)
PEMTPhosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (204 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
PIK3R2Uncharacterized protein. (727 aa)
SMG1-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3310 aa)
U3KI07_FICALFATC domain-containing protein. (185 aa)
U3KID9_FICALUncharacterized protein. (50 aa)
TMPPETransmembrane protein with metallophosphoesterase domain. (438 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
PIGCPhosphatidylinositol glycan anchor biosynthesis class C. (294 aa)
SOCS6Suppressor of cytokine signaling 6. (534 aa)
SOCS1Suppressor of cytokine signaling 1. (207 aa)
SOCS4Suppressor of cytokine signaling 4. (436 aa)
PIGMGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (309 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (455 aa)
PIGWPhosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (506 aa)
U3KL44_FICALTafazzin family protein; Belongs to the taffazin family. (30 aa)
U3KL79_FICALSH2 domain-containing protein. (180 aa)
DOLKDolichol kinase. (523 aa)
MPPE1Metallophosphoesterase 1. (402 aa)
PTPMT1Protein tyrosine phosphatase mitochondrial 1. (167 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1201 aa)
DGKZDiacylglycerol kinase. (988 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (408 aa)
PIGLPhosphatidylinositol glycan anchor biosynthesis class L. (213 aa)
PYURFPIGY upstream reading frame. (79 aa)
LOC101820004Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (329 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (329 aa)
PTDSS1Phosphatidylserine synthase 1. (474 aa)
APOA1Apolipoprotein A1. (266 aa)
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (516 aa)
PIGGPhosphatidylinositol glycan anchor biosynthesis class G. (988 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (374 aa)
U3JRY6_FICALPlsC domain-containing protein. (445 aa)
LOC101817598PlsC domain-containing protein. (446 aa)
FITM2Fat storage inducing transmembrane protein 2. (213 aa)
PIGPPhosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (157 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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