STRINGSTRING
DSP DSP HPS1 HPS1 CPB2 CPB2 FGF2 FGF2 ANXA6 ANXA6 U3K0B5_FICAL U3K0B5_FICAL LOC101808210 LOC101808210 ITGB3 ITGB3 MYOF MYOF SERPIND1 SERPIND1 PRCP PRCP PRSS56 PRSS56 CLDN1 CLDN1 NMNAT1 NMNAT1 APOD APOD MYOZ1 MYOZ1 PLLP PLLP FIBP FIBP ADAM17 ADAM17 CDH7 CDH7 SARM1 SARM1 VASH1 VASH1 F2 F2 CCN1 CCN1 HPS4 HPS4 WNT5A WNT5A SCRIB SCRIB PDCD10 PDCD10 U3K274_FICAL U3K274_FICAL RHOA RHOA FGF1 FGF1 P2RX4 P2RX4 HBEGF HBEGF C8orf82 C8orf82 HGFAC HGFAC P2RX1 P2RX1 U3K5R9_FICAL U3K5R9_FICAL F2R F2R F2RL2 F2RL2 CHMP3 CHMP3 ANO6 ANO6 LYN LYN ARHGAP35 ARHGAP35 ABHD2 ABHD2 NREP NREP ELK3 ELK3 DYSF DYSF HPS5 HPS5 NEFL NEFL SERPING1 SERPING1 MAP2K4 MAP2K4 BLOC1S6 BLOC1S6 MERTK MERTK U3KAV0_FICAL U3KAV0_FICAL U3KAV4_FICAL U3KAV4_FICAL F8 F8 SYT7 SYT7 LOC101812892 LOC101812892 RANGAP1 RANGAP1 GP1BA GP1BA U3KCE5_FICAL U3KCE5_FICAL TGFB2 TGFB2 PLPP3 PLPP3 KCNK2 KCNK2 PDGFB PDGFB SLC1A2 SLC1A2 CD44 CD44 FN1 FN1 BCL2 BCL2 TXN2 TXN2 LAMB2 LAMB2 CDK5 CDK5 FGB FGB FGA FGA FGG FGG INHBB INHBB MORN4 MORN4 PROCR PROCR DTNBP1 DTNBP1 MTR MTR U3KGK7_FICAL U3KGK7_FICAL F2RL3 F2RL3 PDGFA PDGFA CNN2 CNN2 U3KIB6_FICAL U3KIB6_FICAL P2RY1 P2RY1 GP1BB GP1BB P2RY12 P2RY12 ADRA2C ADRA2C U3KKL2_FICAL U3KKL2_FICAL P2RY8 P2RY8 ADRA2A ADRA2A U3KL35_FICAL U3KL35_FICAL ZFP36L1 ZFP36L1 HPS6 HPS6 NOG NOG FZD7 FZD7 FLRT3 FLRT3 ACVRL1 ACVRL1 PLEC PLEC CREB3L2 CREB3L2 MACF1 MACF1 FKBP10 FKBP10 RHOC RHOC U3JDI8_FICAL U3JDI8_FICAL AQP1 AQP1 SRF SRF EVPL EVPL ITGB4 ITGB4 U3JFC3_FICAL U3JFC3_FICAL ENPP4 ENPP4 PROS1 PROS1 U3JGA0_FICAL U3JGA0_FICAL SDC1 SDC1 DST DST LRRC1 LRRC1 GDNF GDNF SLC1A3 SLC1A3 CHMP5 CHMP5 HABP2 HABP2 F3 F3 APOH APOH GNA13 GNA13 SERPINA10 SERPINA10 STXBP3 STXBP3 SYT11 SYT11 PPARA PPARA PTK2 PTK2 F13B F13B U3JJR2_FICAL U3JJR2_FICAL PCSK1 PCSK1 TREM2 TREM2 SERPINC1 SERPINC1 U3JK38_FICAL U3JK38_FICAL PROZ PROZ C6orf89 C6orf89 GAS6 GAS6 SIKE1 SIKE1 ECRG4 ECRG4 KDR KDR U3JM02_FICAL U3JM02_FICAL LOC101821176 LOC101821176 PPARD PPARD CD40LG CD40LG F9 F9 SYTL4 SYTL4 FGFR1OP2 FGFR1OP2 GRIN2A GRIN2A WNT5B WNT5B PIK3CB PIK3CB NMNAT3 NMNAT3 TMEFF2 TMEFF2 F10 F10 F7 F7 ITGB6 ITGB6 EPB41L4B EPB41L4B TFPI TFPI PPL PPL PTPN6 PTPN6 BLOC1S4 BLOC1S4 ENTPD2 ENTPD2 SLC7A11 SLC7A11 HPSE HPSE SDC4 SDC4 EDNRA EDNRA ARHGAP24 ARHGAP24 MPL MPL DCBLD2 DCBLD2 F5 F5 UBASH3B UBASH3B TMPRSS4 TMPRSS4 AMICA1 AMICA1 GAP43 GAP43 MMRN1 MMRN1 TYRO3 TYRO3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSPDesmoplakin. (2193 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (701 aa)
CPB2Carboxypeptidase B2. (422 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (118 aa)
ANXA6Annexin. (671 aa)
U3K0B5_FICALMetallophos domain-containing protein. (209 aa)
LOC101808210Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (780 aa)
MYOFMyoferlin. (2077 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (487 aa)
PRCPProlylcarboxypeptidase. (458 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (572 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (285 aa)
APODApolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
MYOZ1Myozenin 1. (302 aa)
PLLPPlasmolipin. (169 aa)
FIBPFGF1 intracellular binding protein. (364 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
SARM1Sterile alpha and TIR motif containing 1. (630 aa)
VASH1Vasohibin 1. (263 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (608 aa)
CCN1Cellular communication network factor 1. (367 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (692 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
SCRIBScribble planar cell polarity protein. (1377 aa)
PDCD10Programmed cell death 10. (212 aa)
U3K274_FICALG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
RHOARas homolog family member A. (172 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
HBEGFHeparin binding EGF like growth factor. (206 aa)
C8orf82Chromosome 8 open reading frame 82. (216 aa)
HGFACHGF activator. (583 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
U3K5R9_FICALUncharacterized protein. (145 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (381 aa)
CHMP3Uncharacterized protein. (220 aa)
ANO6Anoctamin. (895 aa)
LYNTyrosine-protein kinase. (528 aa)
ARHGAP35Rho GTPase activating protein 35. (1063 aa)
ABHD2Abhydrolase domain containing 2. (426 aa)
NREPNeuronal regeneration related protein. (67 aa)
ELK3ETS transcription factor ELK3. (406 aa)
DYSFDysferlin. (2097 aa)
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1135 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (556 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (457 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (396 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (174 aa)
MERTKMER proto-oncogene, tyrosine kinase. (978 aa)
U3KAV0_FICALUncharacterized protein. (205 aa)
U3KAV4_FICALUncharacterized protein. (494 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2167 aa)
SYT7Synaptotagmin 7. (686 aa)
LOC101812892Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (804 aa)
RANGAP1Ran GTPase activating protein 1. (571 aa)
GP1BALRRCT domain-containing protein. (720 aa)
U3KCE5_FICALUncharacterized protein. (487 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (251 aa)
SLC1A2Amino acid transporter. (572 aa)
CD44CD44 molecule (Indian blood group). (733 aa)
FN1Fibronectin 1. (2307 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TXN2Thioredoxin 2. (141 aa)
LAMB2Laminin subunit beta 2. (1642 aa)
CDK5Cyclin dependent kinase 5. (213 aa)
FGBFibrinogen beta chain. (480 aa)
FGAFibrinogen alpha chain. (760 aa)
FGGFibrinogen gamma chain. (436 aa)
INHBBInhibin subunit beta B. (320 aa)
MORN4MORN repeat containing 4. (146 aa)
PROCRUncharacterized protein. (230 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
MTR5-methyltetrahydrofolate-homocysteine methyltransferase. (1427 aa)
U3KGK7_FICALUncharacterized protein. (482 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (314 aa)
U3KIB6_FICALUncharacterized protein. (63 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (363 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (192 aa)
P2RY12Purinergic receptor P2Y12. (341 aa)
ADRA2CAdrenoceptor alpha 2C. (449 aa)
U3KKL2_FICALUncharacterized protein. (36 aa)
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (357 aa)
ADRA2AAdrenoceptor alpha 2A. (444 aa)
U3KL35_FICALUncharacterized protein. (68 aa)
ZFP36L1ZFP36 ring finger protein like 1. (314 aa)
HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3. (759 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
PLECPlectin. (3536 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (502 aa)
MACF1Microtubule actin crosslinking factor 1. (7232 aa)
FKBP10Peptidylprolyl isomerase. (570 aa)
RHOCUncharacterized protein. (197 aa)
U3JDI8_FICALUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (190 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SRFSerum response factor. (337 aa)
EVPLSH3 domain-containing protein. (2030 aa)
ITGB4Integrin beta. (1733 aa)
U3JFC3_FICALUncharacterized protein. (1004 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (455 aa)
PROS1Protein S. (619 aa)
U3JGA0_FICALUncharacterized protein. (204 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (307 aa)
DSTDystonin. (7453 aa)
LRRC1Leucine rich repeat containing 1. (478 aa)
GDNFGlial cell derived neurotrophic factor. (218 aa)
SLC1A3Amino acid transporter. (543 aa)
CHMP5Charged multivesicular body protein 5. (199 aa)
HABP2Hyaluronan binding protein 2. (558 aa)
F3Coagulation factor III, tissue factor. (293 aa)
APOHApolipoprotein H. (352 aa)
GNA13G protein subunit alpha 13. (291 aa)
SERPINA10Serpin family A member 10; Belongs to the serpin family. (444 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
SYT11Synaptotagmin 11. (442 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
F13BCoagulation factor XIII B chain. (657 aa)
U3JJR2_FICALG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (261 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (453 aa)
U3JK38_FICALUncharacterized protein. (1023 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (425 aa)
C6orf89Chromosome 6 open reading frame 89. (322 aa)
GAS6Growth arrest specific 6. (634 aa)
SIKE1Suppressor of IKBKE 1. (205 aa)
ECRG4ECRG4 augurin precursor. (152 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
U3JM02_FICALUncharacterized protein. (752 aa)
LOC101821176Uncharacterized protein. (473 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (274 aa)
F9Coagulation factor IX. (687 aa)
SYTL4Synaptotagmin like 4. (685 aa)
FGFR1OP2FGFR1 oncogene partner 2. (217 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1323 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (267 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (317 aa)
F10Coagulation factor X. (499 aa)
F7Coagulation factor VII. (425 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (791 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (797 aa)
TFPITissue factor pathway inhibitor. (269 aa)
PPLPeriplakin. (1758 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (136 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (446 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
HPSEHeparanase. (580 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
ARHGAP24Rho GTPase activating protein 24. (766 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (526 aa)
DCBLD2Discoidin, CUB and LCCL domain containing 2. (594 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2102 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (616 aa)
TMPRSS4Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (521 aa)
AMICA1Uncharacterized protein. (67 aa)
GAP43Growth associated protein 43. (247 aa)
MMRN1Multimerin 1. (1191 aa)
TYRO3TYRO3 protein tyrosine kinase. (942 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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