78 items (Ficedula albicollis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRF	Serum response factor. (337 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	FZD5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
	GPR18	G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (318 aa)
	GPR183	G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	RHOH	Ras homolog family member H. (191 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (117 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1040 aa)
	RAG2	Recombination activating 2. (528 aa)
	CCR9	C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	LFNG	Beta-1,3-N-acetylglucosaminyltransferase. (320 aa)
	CARD11	Caspase recruitment domain family member 11. (1166 aa)
	ZAP70	Tyrosine-protein kinase. (614 aa)
	CD83	CD83 molecule. (199 aa)
	CHD9	Chromodomain helicase DNA binding protein 9. (2420 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	ANXA1	Annexin. (372 aa)
	LEPR	Leptin receptor. (1123 aa)
	RORA	RAR related orphan receptor A. (465 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	LEF1	Lymphoid enhancer binding factor 1. (331 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	HLX	H2.0 like homeobox. (175 aa)
	SASH3	SAM and SH3 domain containing 3. (376 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	THEMIS	Thymocyte selection associated. (563 aa)
	TRAF3IP2	SEFIR domain-containing protein. (538 aa)
	TOX	Thymocyte selection associated high mobility group box. (525 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2523 aa)
	CD8A	CD8a molecule. (229 aa)
	IL6	Interleukin 6. (165 aa)
	EOMES	Eomesodermin. (440 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (284 aa)
	IL7	Interleukin 7. (178 aa)
	NKX2-3	NK2 homeobox 3. (309 aa)
	IL21	Uncharacterized protein. (100 aa)
	ABL2	Tyrosine-protein kinase. (1123 aa)
	CD74	CD74 molecule. (289 aa)
	TCF7	Transcription factor 7. (473 aa)
	U3JZ18_FICAL	Uncharacterized protein. (570 aa)
	FZD8	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
	RSAD2	Radical S-adenosyl methionine domain containing 2. (346 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (375 aa)
	FOXN1	Forkhead box N1. (653 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (125 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (683 aa)
	LOC101820502	Ig_4 domain-containing protein. (171 aa)
	CD3E	CD3e molecule. (197 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (3012 aa)
	TNFSF8	TNF superfamily member 8; Belongs to the tumor necrosis factor family. (235 aa)
	RABL3	RAB, member of RAS oncogene family like 3. (236 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (573 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (184 aa)
	CD4	Uncharacterized protein. (487 aa)
	U3JP27_FICAL	Uncharacterized protein. (343 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (583 aa)
	ZBTB1	Zinc finger and BTB domain containing 1. (642 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1238 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1140 aa)
	SP3	Sp3 transcription factor. (690 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1201 aa)
	SEMA4A	Semaphorin 4A; Belongs to the semaphorin family. (707 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (787 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (474 aa)
	RC3H2	Ring finger and CCCH-type domains 2. (1191 aa)
	PKNOX1	PBX/knotted 1 homeobox 1. (436 aa)
	GATA3	GATA binding protein 3. (444 aa)
	GPR89B	Uncharacterized protein. (455 aa)
	TSC1	TSC complex subunit 1. (1153 aa)
	ABL1	Tyrosine-protein kinase. (1127 aa)
	FADD	Fas associated via death domain. (227 aa)
	IL6R	Interleukin 6 receptor. (457 aa)
	LCK	LCK proto-oncogene, Src family tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (506 aa)
	IKZF3	IKAROS family zinc finger 3. (503 aa)
	SOX13	SRY-box transcription factor 13. (611 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSFALP00000001509	ENSFALP00000008528	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL1	CTNNB1	ENSFALP00000001509	ENSFALP00000012792	Tyrosine-protein kinase.	Catenin beta 1.	0.597
ABL2	ABL1	ENSFALP00000008528	ENSFALP00000001509	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL2	CTNNB1	ENSFALP00000008528	ENSFALP00000012792	Tyrosine-protein kinase.	Catenin beta 1.	0.597
ATG5	BCL2	ENSFALP00000012133	ENSFALP00000013568	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 apoptosis regulator.	0.539
ATG5	FADD	ENSFALP00000012133	ENSFALP00000001425	Autophagy protein 5; Involved in autophagic vesicle formation.	Fas associated via death domain.	0.752
ATG5	MTOR	ENSFALP00000012133	ENSFALP00000010712	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.534
BATF	BCL11B	ENSFALP00000006632	ENSFALP00000002668	Basic leucine zipper ATF-like transcription factor.	BAF chromatin remodeling complex subunit BCL11B.	0.538
BCL11B	BATF	ENSFALP00000002668	ENSFALP00000006632	BAF chromatin remodeling complex subunit BCL11B.	Basic leucine zipper ATF-like transcription factor.	0.538
BCL2	ATG5	ENSFALP00000013568	ENSFALP00000012133	BCL2 apoptosis regulator.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.539
BCL2	CD4	ENSFALP00000013568	ENSFALP00000004904	BCL2 apoptosis regulator.	Uncharacterized protein.	0.514
BCL2	CD8A	ENSFALP00000013568	ENSFALP00000010611	BCL2 apoptosis regulator.	CD8a molecule.	0.456
BCL2	CTNNB1	ENSFALP00000013568	ENSFALP00000012792	BCL2 apoptosis regulator.	Catenin beta 1.	0.460
BCL2	FADD	ENSFALP00000013568	ENSFALP00000001425	BCL2 apoptosis regulator.	Fas associated via death domain.	0.464
BCL2	IL6	ENSFALP00000013568	ENSFALP00000010154	BCL2 apoptosis regulator.	Interleukin 6.	0.521
CARD11	RIPK2	ENSFALP00000014481	ENSFALP00000005363	Caspase recruitment domain family member 11.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.421
CARD11	U3JZ18_FICAL	ENSFALP00000014481	ENSFALP00000008022	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.421
CARD11	ZAP70	ENSFALP00000014481	ENSFALP00000014412	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.516
CCR6	CCR7	ENSFALP00000012874	ENSFALP00000000386	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.564
CCR6	CCR9	ENSFALP00000012874	ENSFALP00000014957	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family.	0.498