41 items (Ficedula albicollis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (573 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (184 aa)
	CD40	CD40 molecule. (280 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	MSN	Moesin. (569 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (594 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (288 aa)
	IL20RB	Interleukin 20 receptor subunit beta. (307 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (274 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (702 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1140 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1201 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	RC3H2	Ring finger and CCCH-type domains 2. (1191 aa)
	U3K5P8_FICAL	Uncharacterized protein. (295 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2103 aa)
	U3KAZ9_FICAL	Uncharacterized protein. (742 aa)
	SASH3	SAM and SH3 domain containing 3. (376 aa)
	LEF1	Lymphoid enhancer binding factor 1. (331 aa)
	ITCH	E3 ubiquitin-protein ligase. (878 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	PELI1	Pellino E3 ubiquitin protein ligase 1. (418 aa)
	CARD11	Caspase recruitment domain family member 11. (1166 aa)
	LOC101815751	Uncharacterized protein. (189 aa)
	MALT1	MALT1 paracaspase. (764 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (713 aa)
	U3JG88_FICAL	SLAM domain-containing protein. (68 aa)
	EBI3	Epstein-Barr virus induced 3. (278 aa)
	RASSF5	Ras association domain family member 5. (266 aa)
	HELLS	Helicase, lymphoid specific. (828 aa)
	RASGRP1	RAS guanyl releasing protein 1. (671 aa)
	BCL2L1	BCL2 like 1. (230 aa)
	NTN1	Netrin 1. (582 aa)
	AZI2	5-azacytidine induced 2. (388 aa)
	U3K378_FICAL	TNFR-Cys domain-containing protein. (129 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (284 aa)
	IL7	Interleukin 7. (178 aa)
	FLT3	Fms related tyrosine kinase 3. (992 aa)
	U3JZ18_FICAL	Uncharacterized protein. (570 aa)
	NCSTN	Nicastrin. (657 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BCL2L1	ENSFALP00000013568	ENSFALP00000005771	BCL2 apoptosis regulator.	BCL2 like 1.	0.978
BCL2L1	BCL2	ENSFALP00000005771	ENSFALP00000013568	BCL2 like 1.	BCL2 apoptosis regulator.	0.978
CARD11	MALT1	ENSFALP00000014481	ENSFALP00000010199	Caspase recruitment domain family member 11.	MALT1 paracaspase.	0.856
CARD11	PRKCD	ENSFALP00000014481	ENSFALP00000003635	Caspase recruitment domain family member 11.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.771
CARD11	PRKCQ	ENSFALP00000014481	ENSFALP00000001865	Caspase recruitment domain family member 11.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.771
CARD11	RIPK2	ENSFALP00000014481	ENSFALP00000005363	Caspase recruitment domain family member 11.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.421
CARD11	U3JZ18_FICAL	ENSFALP00000014481	ENSFALP00000008022	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.421
CARD11	U3K5P8_FICAL	ENSFALP00000014481	ENSFALP00000010352	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.787
CARD11	U3KAZ9_FICAL	ENSFALP00000014481	ENSFALP00000012203	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.856
CD40	CD40LG	ENSFALP00000005022	ENSFALP00000003909	CD40 molecule.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.996
CD40	PTPRC	ENSFALP00000005022	ENSFALP00000002847	CD40 molecule.	Protein tyrosine phosphatase receptor type C.	0.400
CD40	TNFSF13B	ENSFALP00000005022	ENSFALP00000004383	CD40 molecule.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.642
CD40	U3K378_FICAL	ENSFALP00000005022	ENSFALP00000009482	CD40 molecule.	TNFR-Cys domain-containing protein.	0.535
CD40LG	CD40	ENSFALP00000003909	ENSFALP00000005022	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD40 molecule.	0.996
CD40LG	IL15	ENSFALP00000003909	ENSFALP00000005155	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin; Belongs to the IL-15/IL-21 family.	0.488
CD40LG	TNFSF13B	ENSFALP00000003909	ENSFALP00000004383	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.769
CD40LG	U3K378_FICAL	ENSFALP00000003909	ENSFALP00000009482	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNFR-Cys domain-containing protein.	0.523
FLT3	IL7R	ENSFALP00000008955	ENSFALP00000002170	Fms related tyrosine kinase 3.	Interleukin 7 receptor.	0.451
FLT3	PTPN6	ENSFALP00000008955	ENSFALP00000004837	Fms related tyrosine kinase 3.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.477
FLT3	PTPRC	ENSFALP00000008955	ENSFALP00000002847	Fms related tyrosine kinase 3.	Protein tyrosine phosphatase receptor type C.	0.419