STRINGSTRING
NR1H4 NR1H4 NR1D1 NR1D1 MPC2 MPC2 STXBP4 STXBP4 ADCY8 ADCY8 HMGN3 HMGN3 KLF7 KLF7 LOC101808801 LOC101808801 BIRC5 BIRC5 SRI SRI PDX1 PDX1 PIM3 PIM3 C2CD2L C2CD2L CFTR CFTR NDUFAF2 NDUFAF2 RFX6 RFX6 PLA2G6 PLA2G6 LRP5 LRP5 GPLD1 GPLD1 GPR68 GPR68
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR1H4Nuclear receptor subfamily 1 group H member 4. (473 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (598 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (98 aa)
STXBP4Syntaxin binding protein 4. (546 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa)
HMGN3High mobility group nucleosomal binding domain 3. (93 aa)
KLF7Kruppel like factor 7. (296 aa)
LOC101808801Uncharacterized protein. (183 aa)
BIRC5Baculoviral IAP repeat containing 5. (140 aa)
SRISorcin. (222 aa)
PDX1Homeobox domain-containing protein. (261 aa)
PIM3Pim-3 proto-oncogene, serine/threonine kinase. (405 aa)
C2CD2LC2CD2 like. (640 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1403 aa)
NDUFAF2NADH:ubiquinone oxidoreductase complex assembly factor 2. (157 aa)
RFX6Regulatory factor X6. (855 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1609 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (836 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (366 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
Server load: low (20%) [HD]