(8 nodes) Positive regulation of mitotic cell cycle spindle assembly checkpoint network (Ficedula albicollis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (347 aa)
	PCID2	PCI domain containing 2. (400 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (206 aa)
	LOC101816865	DUF5595 domain-containing protein. (637 aa)
	GEN1	GEN1 Holliday junction 5' flap endonuclease. (525 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (717 aa)
	NDC80	DUF5595 domain-containing protein. (642 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2400 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GEN1	XRCC3	ENSFALP00000001895	ENSFALP00000002997	GEN1 Holliday junction 5' flap endonuclease.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.634
LOC101816865	MAD2L1	ENSFALP00000000907	ENSFALP00000000894	DUF5595 domain-containing protein.	Mitotic arrest deficient 2 like 1.	0.858
MAD1L1	MAD2L1	ENSFALP00000014519	ENSFALP00000000894	Mitotic arrest deficient 1 like 1.	Mitotic arrest deficient 2 like 1.	0.999
MAD1L1	PCID2	ENSFALP00000014519	ENSFALP00000003349	Mitotic arrest deficient 1 like 1.	PCI domain containing 2.	0.531
MAD1L1	TPR	ENSFALP00000014519	ENSFALP00000003427	Mitotic arrest deficient 1 like 1.	Translocated promoter region, nuclear basket protein.	0.587
MAD2L1	LOC101816865	ENSFALP00000000894	ENSFALP00000000907	Mitotic arrest deficient 2 like 1.	DUF5595 domain-containing protein.	0.858
MAD2L1	MAD1L1	ENSFALP00000000894	ENSFALP00000014519	Mitotic arrest deficient 2 like 1.	Mitotic arrest deficient 1 like 1.	0.999
MAD2L1	NDC80	ENSFALP00000000894	ENSFALP00000006543	Mitotic arrest deficient 2 like 1.	DUF5595 domain-containing protein.	0.858
MAD2L1	PCID2	ENSFALP00000000894	ENSFALP00000003349	Mitotic arrest deficient 2 like 1.	PCI domain containing 2.	0.510
MAD2L1	XRCC3	ENSFALP00000000894	ENSFALP00000002997	Mitotic arrest deficient 2 like 1.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.404
NDC80	MAD2L1	ENSFALP00000006543	ENSFALP00000000894	DUF5595 domain-containing protein.	Mitotic arrest deficient 2 like 1.	0.858
PCID2	MAD1L1	ENSFALP00000003349	ENSFALP00000014519	PCI domain containing 2.	Mitotic arrest deficient 1 like 1.	0.531
PCID2	MAD2L1	ENSFALP00000003349	ENSFALP00000000894	PCI domain containing 2.	Mitotic arrest deficient 2 like 1.	0.510
TPR	MAD1L1	ENSFALP00000003427	ENSFALP00000014519	Translocated promoter region, nuclear basket protein.	Mitotic arrest deficient 1 like 1.	0.587
XRCC3	GEN1	ENSFALP00000002997	ENSFALP00000001895	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	GEN1 Holliday junction 5' flap endonuclease.	0.634
XRCC3	MAD2L1	ENSFALP00000002997	ENSFALP00000000894	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	Mitotic arrest deficient 2 like 1.	0.404