72 items (Ficedula albicollis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U3K4K5_FICAL	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
	BID	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (184 aa)
	MALT1	MALT1 paracaspase. (764 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
	U3K5P8_FICAL	Uncharacterized protein. (295 aa)
	GRAMD4	GRAM domain containing 4. (604 aa)
	F2R	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1053 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (951 aa)
	PIDD1	P53-induced death domain protein 1. (881 aa)
	PAWR	Uncharacterized protein. (85 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (415 aa)
	CTSD	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (396 aa)
	U3KAZ9_FICAL	Uncharacterized protein. (742 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (575 aa)
	USP50	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (338 aa)
	NKX3-1	NK3 homeobox 1. (228 aa)
	HTRA2	HtrA serine peptidase 2. (332 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (219 aa)
	APAF1	Apoptotic peptidase activating factor 1. (1267 aa)
	U3K8N7_FICAL	Uncharacterized protein. (318 aa)
	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain. (204 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (349 aa)
	PML	Uncharacterized protein. (49 aa)
	U3KJX2_FICAL	Uncharacterized protein. (65 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	HIP1	Huntingtin interacting protein 1. (919 aa)
	ARL6IP5	PRA1 family protein. (188 aa)
	SIRT1	Sirtuin 1. (645 aa)
	PDCD5	Programmed cell death 5. (126 aa)
	LCK	LCK proto-oncogene, Src family tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (506 aa)
	TTBK1	Tau tubulin kinase 1. (1369 aa)
	LAPTM5	Lysosomal protein transmembrane 5. (258 aa)
	FADD	Fas associated via death domain. (227 aa)
	CARD9	Caspase recruitment domain family member 9. (542 aa)
	F3	Coagulation factor III, tissue factor. (293 aa)
	LGMN	Legumain. (431 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (436 aa)
	ACVR1C	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (475 aa)
	ACER2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
	CASP8AP2	Caspase 8 associated protein 2. (2043 aa)
	PDCD2	Programmed cell death 2. (198 aa)
	BAK1	BCL2 antagonist/killer 1. (213 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (507 aa)
	U3JNE7_FICAL	Uncharacterized protein; Belongs to the peptidase C14A family. (468 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (484 aa)
	CFLAR	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (489 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (594 aa)
	TFAP4	Transcription factor AP-4. (327 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (422 aa)
	FAM162A	Family with sequence similarity 162 member A. (158 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (573 aa)
	UACA	Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1379 aa)
	TNFSF15	TNF superfamily member 15. (242 aa)
	ASPH	Aspartate beta-hydroxylase. (776 aa)
	BCL10	CARD domain-containing protein. (214 aa)
	CCN1	Cellular communication network factor 1. (367 aa)
	IFT57	Intraflagellar transport 57. (418 aa)
	REST	RE1 silencing transcription factor. (893 aa)
	NGFR	Nerve growth factor receptor. (409 aa)
	FAS	Fas cell surface death receptor. (369 aa)
	U3JZ18_FICAL	Uncharacterized protein. (570 aa)
	DAP	Uncharacterized protein. (86 aa)
	FASLG	Fas ligand; Belongs to the tumor necrosis factor family. (283 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (319 aa)
	U3K017_FICAL	Uncharacterized protein. (278 aa)
	CYFIP2	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
	TNFSF10	TNF superfamily member 10; Belongs to the tumor necrosis factor family. (301 aa)
	U3K1D1_FICAL	Uncharacterized protein. (76 aa)
	MYCN	MYCN proto-oncogene, bHLH transcription factor. (464 aa)
	DIABLO	Uncharacterized protein. (273 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1057 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIFM1	APAF1	ENSFALP00000012130	ENSFALP00000011473	Apoptosis inducing factor mitochondria associated 1.	Apoptotic peptidase activating factor 1.	0.512
AIFM1	CASP9	ENSFALP00000012130	ENSFALP00000010959	Apoptosis inducing factor mitochondria associated 1.	Caspase 9; Belongs to the peptidase C14A family.	0.523
AIFM1	DIABLO	ENSFALP00000012130	ENSFALP00000009500	Apoptosis inducing factor mitochondria associated 1.	Uncharacterized protein.	0.525
AIFM1	U3K4K5_FICAL	ENSFALP00000012130	ENSFALP00000009959	Apoptosis inducing factor mitochondria associated 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.524
APAF1	AIFM1	ENSFALP00000011473	ENSFALP00000012130	Apoptotic peptidase activating factor 1.	Apoptosis inducing factor mitochondria associated 1.	0.512
APAF1	BAK1	ENSFALP00000011473	ENSFALP00000004061	Apoptotic peptidase activating factor 1.	BCL2 antagonist/killer 1.	0.647
APAF1	CASP10	ENSFALP00000011473	ENSFALP00000004303	Apoptotic peptidase activating factor 1.	Caspase 10; Belongs to the peptidase C14A family.	0.810
APAF1	CASP2	ENSFALP00000011473	ENSFALP00000004700	Apoptotic peptidase activating factor 1.	Caspase 2; Belongs to the peptidase C14A family.	0.859
APAF1	CASP8	ENSFALP00000011473	ENSFALP00000004295	Apoptotic peptidase activating factor 1.	Caspase 8; Belongs to the peptidase C14A family.	0.844
APAF1	CASP9	ENSFALP00000011473	ENSFALP00000010959	Apoptotic peptidase activating factor 1.	Caspase 9; Belongs to the peptidase C14A family.	0.991
APAF1	CFLAR	ENSFALP00000011473	ENSFALP00000004309	Apoptotic peptidase activating factor 1.	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.	0.800
APAF1	DIABLO	ENSFALP00000011473	ENSFALP00000009500	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.961
APAF1	FADD	ENSFALP00000011473	ENSFALP00000001425	Apoptotic peptidase activating factor 1.	Fas associated via death domain.	0.540
APAF1	FASLG	ENSFALP00000011473	ENSFALP00000008132	Apoptotic peptidase activating factor 1.	Fas ligand; Belongs to the tumor necrosis factor family.	0.577
APAF1	HTRA2	ENSFALP00000011473	ENSFALP00000011542	Apoptotic peptidase activating factor 1.	HtrA serine peptidase 2.	0.461
APAF1	LGMN	ENSFALP00000011473	ENSFALP00000002537	Apoptotic peptidase activating factor 1.	Legumain.	0.533
APAF1	PIDD1	ENSFALP00000011473	ENSFALP00000010925	Apoptotic peptidase activating factor 1.	P53-induced death domain protein 1.	0.417
APAF1	U3JNE7_FICAL	ENSFALP00000011473	ENSFALP00000004301	Apoptotic peptidase activating factor 1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.844
APAF1	U3K1D1_FICAL	ENSFALP00000011473	ENSFALP00000008835	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.690
APAF1	U3K4K5_FICAL	ENSFALP00000011473	ENSFALP00000009959	Apoptotic peptidase activating factor 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999