51 items (Ficedula albicollis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (461 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	TRIM32	Tripartite motif containing 32. (647 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	MCL1	Uncharacterized protein. (91 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	TRIAP1	TP53 regulated inhibitor of apoptosis 1. (76 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	PARL	Rhomboid domain-containing protein. (285 aa)
	PTTG1IP	PTTG1 interacting protein. (179 aa)
	MARCHF7	Membrane associated ring-CH-type finger 7. (714 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (584 aa)
	IVNS1ABP	Influenza virus NS1A binding protein. (552 aa)
	U3JJU8_FICAL	Uncharacterized protein. (79 aa)
	BAG5	BCL2 associated athanogene 5. (473 aa)
	CLU	Clusterin; Belongs to the clusterin family. (392 aa)
	ATAD5	ATPase family AAA domain containing 5. (1816 aa)
	CREB3	cAMP responsive element binding protein 3. (428 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (786 aa)
	URI1	URI1 prefoldin like chaperone. (443 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (146 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (620 aa)
	OPA1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (887 aa)
	HELLS	Helicase, lymphoid specific. (828 aa)
	HERPUD1	Homocysteine inducible ER protein with ubiquitin like domain 1. (383 aa)
	TMEM161A	Transmembrane protein 161A. (420 aa)
	NDUFS3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (308 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (499 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (464 aa)
	SNAI2	Uncharacterized protein. (268 aa)
	TXNDC12	Thioredoxin domain containing 12. (166 aa)
	SRC	Tyrosine-protein kinase. (539 aa)
	WFS1	Wolframin ER transmembrane glycoprotein. (873 aa)
	HYOU1	Hypoxia up-regulated 1. (984 aa)
	LRRK2	Leucine rich repeat kinase 2. (2450 aa)
	SELENOS	Uncharacterized protein. (202 aa)
	PINK1	PTEN induced kinase 1. (473 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1239 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	SIRT1	Sirtuin 1. (645 aa)
	BCL2L1	BCL2 like 1. (230 aa)
	MMP9	Matrix metallopeptidase 9. (709 aa)
	TRAP1	TNF receptor associated protein 1. (709 aa)
	NME5	NME/NM23 family member 5; Belongs to the NDK family. (208 aa)
	U3JZ40_FICAL	Uncharacterized protein. (147 aa)
	DDIAS	Rep_fac-A_C domain-containing protein. (419 aa)
	CD74	CD74 molecule. (289 aa)
	TPT1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (173 aa)
	XBP1	X-box binding protein 1. (264 aa)
	PDX1	Homeobox domain-containing protein. (261 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (194 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	HELLS	ENSFALP00000002381	ENSFALP00000007445	ATPase family AAA domain containing 5.	Helicase, lymphoid specific.	0.445
BAG5	PRKN	ENSFALP00000002982	ENSFALP00000012711	BCL2 associated athanogene 5.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.457
BCL2	BCL2L1	ENSFALP00000013568	ENSFALP00000005771	BCL2 apoptosis regulator.	BCL2 like 1.	0.978
BCL2	MCL1	ENSFALP00000013568	ENSFALP00000015690	BCL2 apoptosis regulator.	Uncharacterized protein.	0.727
BCL2	MMP9	ENSFALP00000013568	ENSFALP00000004869	BCL2 apoptosis regulator.	Matrix metallopeptidase 9.	0.525
BCL2	SIRT1	ENSFALP00000013568	ENSFALP00000013509	BCL2 apoptosis regulator.	Sirtuin 1.	0.456
BCL2L1	BCL2	ENSFALP00000005771	ENSFALP00000013568	BCL2 like 1.	BCL2 apoptosis regulator.	0.978
BCL2L1	MCL1	ENSFALP00000005771	ENSFALP00000015690	BCL2 like 1.	Uncharacterized protein.	0.540
BCL2L1	PINK1	ENSFALP00000005771	ENSFALP00000010988	BCL2 like 1.	PTEN induced kinase 1.	0.932
CD74	NDUFS3	ENSFALP00000008366	ENSFALP00000006688	CD74 molecule.	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.	0.449
CD74	NME5	ENSFALP00000008366	ENSFALP00000007977	CD74 molecule.	NME/NM23 family member 5; Belongs to the NDK family.	0.611
CD74	SOD2	ENSFALP00000008366	ENSFALP00000012652	CD74 molecule.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.661
CD74	TPT1	ENSFALP00000008366	ENSFALP00000008525	CD74 molecule.	Tumor protein, translationally-controlled 1; Belongs to the TCTP family.	0.812
CD74	XBP1	ENSFALP00000008366	ENSFALP00000008660	CD74 molecule.	X-box binding protein 1.	0.402
CREB3	CREB3L1	ENSFALP00000002303	ENSFALP00000006514	cAMP responsive element binding protein 3.	cAMP responsive element binding protein 3 like 1.	0.924
CREB3L1	CREB3	ENSFALP00000006514	ENSFALP00000002303	cAMP responsive element binding protein 3 like 1.	cAMP responsive element binding protein 3.	0.924
HELLS	ATAD5	ENSFALP00000007445	ENSFALP00000002381	Helicase, lymphoid specific.	ATPase family AAA domain containing 5.	0.445
HSPB1	TRAP1	ENSFALP00000009992	ENSFALP00000004499	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	TNF receptor associated protein 1.	0.480
HYOU1	TRAP1	ENSFALP00000010293	ENSFALP00000004499	Hypoxia up-regulated 1.	TNF receptor associated protein 1.	0.639
HYOU1	XBP1	ENSFALP00000010293	ENSFALP00000008660	Hypoxia up-regulated 1.	X-box binding protein 1.	0.633