(41 nodes) G-protein mediated events network (Ficedula albicollis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCLK1	Doublecortin like kinase 1. (729 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
	GNAL	G protein subunit alpha L. (379 aa)
	PRKACB	Uncharacterized protein; Belongs to the protein kinase superfamily. (401 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (713 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (382 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1241 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	GNAQ	Uncharacterized protein. (320 aa)
	PLA2G4A	Phospholipase A2. (753 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (702 aa)
	PDE1A	Phosphodiesterase. (504 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1345 aa)
	U3JPS4_FICAL	Uncharacterized protein; Belongs to the protein kinase superfamily. (318 aa)
	THAP1	THAP domain containing 1. (213 aa)
	LRBA	LPS responsive beige-like anchor protein. (2878 aa)
	SNX19	Sorting nexin 19. (930 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (973 aa)
	NBEA	Neurobeachin. (932 aa)
	GNAO1	G protein subunit alpha o1. (320 aa)
	U3KJ11_FICAL	Uncharacterized protein. (64 aa)
	U3KIX4_FICAL	THAP-type domain-containing protein. (52 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	GNA11	G protein subunit alpha 11. (315 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1127 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (304 aa)
	PDE1C	Phosphodiesterase. (726 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1124 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV. (324 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	PDE1B	Phosphodiesterase. (425 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (330 aa)
	CAMKK1	Calcium/calmodulin dependent protein kinase kinase 1. (507 aa)
	CAMKK2	Protein kinase domain-containing protein. (515 aa)
	U3K2M1_FICAL	PLCXc domain-containing protein. (334 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSFALP00000013795	ENSFALP00000007485	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.431
ADCY1	ADCY5	ENSFALP00000013795	ENSFALP00000013939	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.432
ADCY1	ADCY6	ENSFALP00000013795	ENSFALP00000000131	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY7	ENSFALP00000013795	ENSFALP00000000090	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.431
ADCY1	ADCY8	ENSFALP00000013795	ENSFALP00000002681	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.956
ADCY1	ADCY9	ENSFALP00000013795	ENSFALP00000004505	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.661
ADCY1	GNAI1	ENSFALP00000013795	ENSFALP00000010922	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.799
ADCY1	GNAI2	ENSFALP00000013795	ENSFALP00000009199	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.799
ADCY1	GNAI3	ENSFALP00000013795	ENSFALP00000002995	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.799
ADCY1	GNAL	ENSFALP00000013795	ENSFALP00000006695	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.964
ADCY1	GNAO1	ENSFALP00000013795	ENSFALP00000007920	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha o1.	0.450
ADCY1	PDE1A	ENSFALP00000013795	ENSFALP00000003757	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.676
ADCY1	PDE1C	ENSFALP00000013795	ENSFALP00000013694	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.676
ADCY1	PRKACB	ENSFALP00000013795	ENSFALP00000006254	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.932
ADCY2	ADCY1	ENSFALP00000007485	ENSFALP00000013795	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.431
ADCY2	ADCY5	ENSFALP00000007485	ENSFALP00000013939	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.640
ADCY2	ADCY6	ENSFALP00000007485	ENSFALP00000000131	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.646
ADCY2	ADCY8	ENSFALP00000007485	ENSFALP00000002681	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.431
ADCY2	ADCY9	ENSFALP00000007485	ENSFALP00000004505	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.551
ADCY2	GNAI1	ENSFALP00000007485	ENSFALP00000010922	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.793