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KCND2 KCND2 ATP2B4 ATP2B4 U3JB93_FICAL U3JB93_FICAL FAHD2A FAHD2A KCNIP3 KCNIP3 NPR2 NPR2 LOC101821431 LOC101821431 U3JC54_FICAL U3JC54_FICAL GUCY1A2 GUCY1A2 U3JCX4_FICAL U3JCX4_FICAL KCND3 KCND3 LOC101807791 LOC101807791 U3JDB7_FICAL U3JDB7_FICAL PDE5A PDE5A TPM3 TPM3 TMOD1 TMOD1 CACNA1G CACNA1G TMOD4 TMOD4 U3JG75_FICAL U3JG75_FICAL LOC101810276 LOC101810276 TPM2 TPM2 KCNK18 KCNK18 TLN1 TLN1 SLC8A1 SLC8A1 LMOD1 LMOD1 CACNG4 CACNG4 CACNG5 CACNG5 DMD DMD TNNT2 TNNT2 TNNI1 TNNI1 KCNK9 KCNK9 SORBS3 SORBS3 CORIN CORIN ACTA1 ACTA1 KCNIP1 KCNIP1 LOC101810052 LOC101810052 ABCC9 ABCC9 ITPR3 ITPR3 ITPR2 ITPR2 PHEX PHEX DES DES FGF14 FGF14 U3JPP6_FICAL U3JPP6_FICAL TNNC2 TNNC2 U3JPW9_FICAL U3JPW9_FICAL LOC101816985 LOC101816985 SLC8A3 SLC8A3 MME MME U3JR53_FICAL U3JR53_FICAL KCNE1 KCNE1 MYL3 MYL3 KCNK15 KCNK15 ASPH ASPH SLC8A2 SLC8A2 RYR3 RYR3 U3JSQ3_FICAL U3JSQ3_FICAL ACTC1 ACTC1 ATP1B1 ATP1B1 U3JT83_FICAL U3JT83_FICAL SCN3B SCN3B MYH7B MYH7B FXYD6 FXYD6 SCN4B SCN4B CASQ2 CASQ2 ATP1A1 ATP1A1 U3JUX4_FICAL U3JUX4_FICAL MYL12B MYL12B MYBPC3 MYBPC3 MYH15 MYH15 KCNA5 KCNA5 U3JW60_FICAL U3JW60_FICAL U3JWC9_FICAL U3JWC9_FICAL LOC101819537 LOC101819537 ATP1B3 ATP1B3 VCL VCL TRPC1 TRPC1 SORBS1 SORBS1 SORBS1-2 SORBS1-2 FGF12 FGF12 MYH7 MYH7 CACNB2 CACNB2 VIM VIM LOC101809654 LOC101809654 PXN PXN ACTA2 ACTA2 MYOF MYOF SRI SRI U3JZM9_FICAL U3JZM9_FICAL ANXA6 ANXA6 SCN3A SCN3A U3K121_FICAL U3K121_FICAL SCN2A SCN2A SCN1A SCN1A ASPHD2 ASPHD2 KCNIP2 KCNIP2 U3K2B4_FICAL U3K2B4_FICAL NKX2-5 NKX2-5 TNNC1 TNNC1 CACNA2D2 CACNA2D2 MYL2 MYL2 MYBPC1 MYBPC1 STIM2 STIM2 ORAI1 ORAI1 SMIM20 SMIM20 RNF222 RNF222 ATP2A2 ATP2A2 KCNIP4 KCNIP4 U3K3X5_FICAL U3K3X5_FICAL MYL10 MYL10 ORAI2 ORAI2 MAST2 MAST2 MMEL1 MMEL1 CALD1 CALD1 MAST4 MAST4 LMOD2 LMOD2 ATP2A3 ATP2A3 U3K5X4_FICAL U3K5X4_FICAL U3K649_FICAL U3K649_FICAL NPPB NPPB STIM1 STIM1 U3K6N9_FICAL U3K6N9_FICAL AKAP9 AKAP9 CACNA2D1 CACNA2D1 ATP2B1 ATP2B1 ITGA1 ITGA1 LOC101807400 LOC101807400 GATD1 GATD1 KCNK16 KCNK16 KCNK17 KCNK17 KCNK5 KCNK5 DYSF DYSF U3K924_FICAL U3K924_FICAL KCNK12 KCNK12 U3KA67_FICAL U3KA67_FICAL KCNQ1 KCNQ1 TNNT3 TNNT3 TNNI2 TNNI2 MYH1 MYH1 U3KB47_FICAL U3KB47_FICAL TMOD2 TMOD2 U3KBD4_FICAL U3KBD4_FICAL U3KBE3_FICAL U3KBE3_FICAL TMOD3 TMOD3 CLIC2 CLIC2 SORBS2 SORBS2 LOC101813636 LOC101813636 KCNK2 KCNK2 CACNA1I CACNA1I KCNK13 KCNK13 KCNK10 KCNK10 KCNJ4 KCNJ4 MYL9 MYL9 TLN2 TLN2 TPM1 TPM1 UTRN UTRN MYL1 MYL1 GUCY1A1 GUCY1A1 LMOD3 LMOD3 RYR2 RYR2 ACTN2 ACTN2 TPM4 TPM4 ITGB5 ITGB5 ITPR1 ITPR1 KCNK1 KCNK1 CACNA1H CACNA1H SCN4A SCN4A KCNJ12 KCNJ12 MAST3 MAST3 NEB NEB LOC101818535 LOC101818535 U3KHW1_FICAL U3KHW1_FICAL KCNE2 KCNE2 TLNRD1 TLNRD1 U3KII5_FICAL U3KII5_FICAL KCNJ11 KCNJ11 KCNE3 KCNE3 U3KK46_FICAL U3KK46_FICAL KCNJ2 KCNJ2 KCNE4 KCNE4 PLN PLN
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (346 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1166 aa)
U3JB93_FICALUncharacterized protein. (905 aa)
FAHD2AFAA_hydrolase domain-containing protein. (278 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (227 aa)
NPR2Guanylate cyclase. (976 aa)
LOC101821431Guanylate cyclase. (828 aa)
U3JC54_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1893 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
U3JCX4_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1946 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
LOC101807791Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1944 aa)
U3JDB7_FICALUncharacterized protein. (1403 aa)
PDE5APhosphodiesterase. (845 aa)
TPM3Uncharacterized protein; Belongs to the tropomyosin family. (312 aa)
TMOD1Tropomodulin 1. (349 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2322 aa)
TMOD4Uncharacterized protein. (371 aa)
U3JG75_FICALUncharacterized protein. (48 aa)
LOC101810276Uncharacterized protein. (137 aa)
TPM2Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (378 aa)
TLN1Talin 1. (2544 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (988 aa)
LMOD1Leiomodin 1. (623 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (279 aa)
DMDDystrophin. (1573 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
SORBS3Sorbin and SH3 domain containing 3. (624 aa)
CORINCorin, serine peptidase. (1097 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (217 aa)
LOC101810052Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (275 aa)
ABCC9ATP binding cassette subfamily C member 9. (1574 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2692 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (747 aa)
DESDesmin; Belongs to the intermediate filament family. (463 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
U3JPP6_FICALVWFA domain-containing protein. (535 aa)
TNNC2Troponin C2, fast skeletal type. (178 aa)
U3JPW9_FICALIon_trans domain-containing protein; Belongs to the potassium channel family. (370 aa)
LOC101816985Uncharacterized protein. (181 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
MMEMembrane metalloendopeptidase. (698 aa)
U3JR53_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1736 aa)
KCNE1Uncharacterized protein. (127 aa)
MYL3Uncharacterized protein. (193 aa)
KCNK15Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (372 aa)
ASPHAspartate beta-hydroxylase. (776 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (774 aa)
RYR3Uncharacterized protein. (4330 aa)
U3JSQ3_FICALIns145_P3_rec domain-containing protein. (93 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
U3JT83_FICALUncharacterized protein. (208 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
MYH7BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (96 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (404 aa)
ATP1A1ATPase Na+/K+ transporting subunit alpha 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1101 aa)
U3JUX4_FICALUncharacterized protein. (193 aa)
MYL12BUncharacterized protein. (172 aa)
MYBPC3Myosin binding protein C, cardiac. (1276 aa)
MYH15Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (429 aa)
U3JW60_FICALSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1973 aa)
U3JWC9_FICALGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (670 aa)
LOC101819537Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2040 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
VCLVinculin. (1168 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (736 aa)
SORBS1Sorbin and SH3 domain containing 1. (1284 aa)
SORBS1-2SoHo domain-containing protein. (487 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (611 aa)
VIMVimentin; Belongs to the intermediate filament family. (447 aa)
LOC101809654Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (572 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
MYOFMyoferlin. (2077 aa)
SRISorcin. (222 aa)
U3JZM9_FICALGuKc domain-containing protein. (418 aa)
ANXA6Annexin. (671 aa)
SCN3ASodium voltage-gated channel alpha subunit 3. (1947 aa)
U3K121_FICALUncharacterized protein. (139 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1875 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1640 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (367 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (225 aa)
U3K2B4_FICALCation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (765 aa)
NKX2-5NK2 homeobox 5. (302 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1065 aa)
MYL2Myosin light chain 2. (165 aa)
MYBPC1Myosin binding protein C, slow type. (1226 aa)
STIM2Stromal interaction molecule 2. (678 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (228 aa)
SMIM20Small integral membrane protein 20. (68 aa)
RNF222Ring finger protein 222. (211 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1059 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (267 aa)
U3K3X5_FICALSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1826 aa)
MYL10Uncharacterized protein. (165 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (257 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1950 aa)
MMEL1Membrane metalloendopeptidase like 1. (773 aa)
CALD1Caldesmon 1. (748 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2380 aa)
LMOD2Leiomodin 2. (454 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1048 aa)
U3K5X4_FICALUncharacterized protein; Belongs to the potassium channel family. (260 aa)
U3K649_FICALGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (231 aa)
NPPBUncharacterized protein. (140 aa)
STIM1Stromal interaction molecule 1. (607 aa)
U3K6N9_FICALCation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (316 aa)
AKAP9A-kinase anchoring protein 9. (2608 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1062 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1176 aa)
ITGA1Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (653 aa)
LOC101807400Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1921 aa)
GATD1Glutamine amidotransferase like class 1 domain containing 1. (220 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (267 aa)
KCNK17Potassium channel subfamily K member. (322 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (482 aa)
DYSFDysferlin. (2097 aa)
U3K924_FICALUncharacterized protein. (188 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (329 aa)
U3KA67_FICALAsp-B-Hydro_N domain-containing protein. (158 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (595 aa)
TNNT3Troponin T3, fast skeletal type. (266 aa)
TNNI2Troponin I2, fast skeletal type. (194 aa)
MYH1Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1909 aa)
U3KB47_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
TMOD2Tropomodulin 2. (351 aa)
U3KBD4_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1899 aa)
U3KBE3_FICALUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (627 aa)
TMOD3Tropomodulin 3. (351 aa)
CLIC2Chloride intracellular channel 2. (247 aa)
SORBS2Sorbin and SH3 domain containing 2. (1426 aa)
LOC101813636Uncharacterized protein. (787 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1875 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (381 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (523 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (450 aa)
MYL9Myosin light chain 9. (180 aa)
TLN2Talin 2. (2542 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
UTRNUtrophin; May play a role in anchoring the cytoskeleton to the plasma membrane. (3432 aa)
MYL1Myosin light chain 1. (190 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
LMOD3Leiomodin 3. (574 aa)
RYR2Ryanodine receptor 2. (4972 aa)
ACTN2Actinin alpha 2. (897 aa)
TPM4Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (807 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2762 aa)
KCNK1Potassium channel subfamily K member. (331 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2148 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1805 aa)
KCNJ12Uncharacterized protein. (429 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1410 aa)
NEBUncharacterized protein. (4845 aa)
LOC1018185353Beta_HSD domain-containing protein. (414 aa)
U3KHW1_FICAL3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (371 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (122 aa)
TLNRD1Talin rod domain containing 1. (355 aa)
U3KII5_FICALUncharacterized protein. (93 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (396 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (95 aa)
U3KK46_FICALUncharacterized protein. (163 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (163 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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