14 items (Ficedula albicollis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRP6	LDL receptor related protein 6. (1460 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	LOC101814614	Methyltransf_11 domain-containing protein. (271 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1609 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	DVL1	Dishevelled segment polarity protein 1. (687 aa)
	DVL3	Dishevelled segment polarity protein 3. (671 aa)
	HMGXB3	HMG-box containing 3. (1307 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	WNT8B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (395 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
	U3JCA6_FICAL	Uncharacterized protein. (69 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV3	ENSFALP00000010549	ENSFALP00000014211	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.960
CAV1	GSK3B	ENSFALP00000010549	ENSFALP00000005581	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.408
CAV1	LRP5	ENSFALP00000010549	ENSFALP00000013261	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.445
CAV1	LRP6	ENSFALP00000010549	ENSFALP00000002716	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	LDL receptor related protein 6.	0.619
CAV1	WNT3A	ENSFALP00000010549	ENSFALP00000001133	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.496
CAV3	CAV1	ENSFALP00000014211	ENSFALP00000010549	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.960
CAV3	GSK3B	ENSFALP00000014211	ENSFALP00000005581	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.515
CAV3	LRP5	ENSFALP00000014211	ENSFALP00000013261	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.624
CAV3	LRP6	ENSFALP00000014211	ENSFALP00000002716	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	LDL receptor related protein 6.	0.761
CAV3	WNT3A	ENSFALP00000014211	ENSFALP00000001133	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.558
DVL1	DVL3	ENSFALP00000009680	ENSFALP00000008289	Dishevelled segment polarity protein 1.	Dishevelled segment polarity protein 3.	0.933
DVL1	GSK3B	ENSFALP00000009680	ENSFALP00000005581	Dishevelled segment polarity protein 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.971
DVL1	LRP5	ENSFALP00000009680	ENSFALP00000013261	Dishevelled segment polarity protein 1.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.847
DVL1	LRP6	ENSFALP00000009680	ENSFALP00000002716	Dishevelled segment polarity protein 1.	LDL receptor related protein 6.	0.850
DVL1	WNT1	ENSFALP00000009680	ENSFALP00000000160	Dishevelled segment polarity protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.590
DVL1	WNT3A	ENSFALP00000009680	ENSFALP00000001133	Dishevelled segment polarity protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.506
DVL1	WNT8A	ENSFALP00000009680	ENSFALP00000007975	Dishevelled segment polarity protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.543
DVL1	WNT8B	ENSFALP00000009680	ENSFALP00000007670	Dishevelled segment polarity protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.543
DVL3	DVL1	ENSFALP00000008289	ENSFALP00000009680	Dishevelled segment polarity protein 3.	Dishevelled segment polarity protein 1.	0.933
DVL3	GSK3B	ENSFALP00000008289	ENSFALP00000005581	Dishevelled segment polarity protein 3.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.971