STRINGSTRING
DVL3 DVL3 CAV1 CAV1 LRP5 LRP5 LOC101814614 LOC101814614 CAV3 CAV3 LRP6 LRP6 GSK3B GSK3B WNT8B WNT8B WNT8A WNT8A HMGXB3 HMGXB3 DVL1 DVL1 WNT1 WNT1 U3JCA6_FICAL U3JCA6_FICAL WNT3A WNT3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVL3Dishevelled segment polarity protein 3. (671 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1609 aa)
LOC101814614Methyltransf_11 domain-containing protein. (271 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LRP6LDL receptor related protein 6. (1460 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (395 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
HMGXB3HMG-box containing 3. (1307 aa)
DVL1Dishevelled segment polarity protein 1. (687 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
U3JCA6_FICALUncharacterized protein. (69 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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