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ATP1A1 ATP1A1 U3K649_FICAL U3K649_FICAL KCND2 KCND2 U3K5X4_FICAL U3K5X4_FICAL ATP2A3 ATP2A3 MAST4 MAST4 MMEL1 MMEL1 MAST2 MAST2 ORAI2 ORAI2 U3K3X5_FICAL U3K3X5_FICAL KCNIP4 KCNIP4 ATP2A2 ATP2A2 ORAI1 ORAI1 STIM2 STIM2 CACNA2D2 CACNA2D2 NKX2-5 NKX2-5 U3K2B4_FICAL U3K2B4_FICAL KCNIP2 KCNIP2 ASPHD2 ASPHD2 SCN1A SCN1A SCN2A SCN2A U3K121_FICAL U3K121_FICAL SCN3A SCN3A U3JZM9_FICAL U3JZM9_FICAL SRI SRI CACNB2 CACNB2 FGF12 FGF12 TRPC1 TRPC1 ATP1B3 ATP1B3 LOC101819537 LOC101819537 LOC101810052 LOC101810052 KCNIP1 KCNIP1 CORIN CORIN KCNK9 KCNK9 CACNG5 CACNG5 CACNG4 CACNG4 SLC8A1 SLC8A1 KCNK18 KCNK18 LOC101810276 LOC101810276 U3JG75_FICAL U3JG75_FICAL U3JDB7_FICAL U3JDB7_FICAL KCND3 KCND3 LOC101821431 LOC101821431 NPR2 NPR2 KCNIP3 KCNIP3 FAHD2A FAHD2A U3JB93_FICAL U3JB93_FICAL ATP2B4 ATP2B4 NPPB NPPB KCNJ2 KCNJ2 KCNE4 KCNE4 PLN PLN U3KK46_FICAL U3KK46_FICAL KCNE3 KCNE3 KCNJ11 KCNJ11 U3KII5_FICAL U3KII5_FICAL KCNE2 KCNE2 U3KHW1_FICAL U3KHW1_FICAL LOC101818535 LOC101818535 MAST3 MAST3 KCNJ12 KCNJ12 SCN4A SCN4A KCNK1 KCNK1 ITPR1 ITPR1 RYR2 RYR2 KCNJ4 KCNJ4 KCNK10 KCNK10 KCNK13 KCNK13 KCNK2 KCNK2 CLIC2 CLIC2 KCNQ1 KCNQ1 U3KA67_FICAL U3KA67_FICAL KCNK12 KCNK12 U3K924_FICAL U3K924_FICAL KCNK5 KCNK5 KCNK17 KCNK17 KCNK16 KCNK16 ATP2B1 ATP2B1 CACNA2D1 CACNA2D1 AKAP9 AKAP9 U3K6N9_FICAL U3K6N9_FICAL STIM1 STIM1 U3JW60_FICAL U3JW60_FICAL KCNA5 KCNA5 CASQ2 CASQ2 SCN4B SCN4B FXYD6 FXYD6 SCN3B SCN3B ATP1B1 ATP1B1 U3JSQ3_FICAL U3JSQ3_FICAL RYR3 RYR3 SLC8A2 SLC8A2 ASPH ASPH KCNK15 KCNK15 KCNE1 KCNE1 MME MME SLC8A3 SLC8A3 U3JPW9_FICAL U3JPW9_FICAL FGF14 FGF14 PHEX PHEX ITPR2 ITPR2 ITPR3 ITPR3 ABCC9 ABCC9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1A1ATPase Na+/K+ transporting subunit alpha 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1101 aa)
U3K649_FICALGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (231 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (346 aa)
U3K5X4_FICALUncharacterized protein; Belongs to the potassium channel family. (260 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1048 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2380 aa)
MMEL1Membrane metalloendopeptidase like 1. (773 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1950 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (257 aa)
U3K3X5_FICALSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1826 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (267 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1059 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (228 aa)
STIM2Stromal interaction molecule 2. (678 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1065 aa)
NKX2-5NK2 homeobox 5. (302 aa)
U3K2B4_FICALCation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (765 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (225 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (367 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1640 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1875 aa)
U3K121_FICALUncharacterized protein. (139 aa)
SCN3ASodium voltage-gated channel alpha subunit 3. (1947 aa)
U3JZM9_FICALGuKc domain-containing protein. (418 aa)
SRISorcin. (222 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (611 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (736 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
LOC101819537Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2040 aa)
LOC101810052Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (275 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (217 aa)
CORINCorin, serine peptidase. (1097 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (279 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (988 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (378 aa)
LOC101810276Uncharacterized protein. (137 aa)
U3JG75_FICALUncharacterized protein. (48 aa)
U3JDB7_FICALUncharacterized protein. (1403 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
LOC101821431Guanylate cyclase. (828 aa)
NPR2Guanylate cyclase. (976 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (227 aa)
FAHD2AFAA_hydrolase domain-containing protein. (278 aa)
U3JB93_FICALUncharacterized protein. (905 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1166 aa)
NPPBUncharacterized protein. (140 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (163 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
U3KK46_FICALUncharacterized protein. (163 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (95 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (396 aa)
U3KII5_FICALUncharacterized protein. (93 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (122 aa)
U3KHW1_FICAL3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (371 aa)
LOC1018185353Beta_HSD domain-containing protein. (414 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1410 aa)
KCNJ12Uncharacterized protein. (429 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1805 aa)
KCNK1Potassium channel subfamily K member. (331 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2762 aa)
RYR2Ryanodine receptor 2. (4972 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (450 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (523 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (381 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
CLIC2Chloride intracellular channel 2. (247 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (595 aa)
U3KA67_FICALAsp-B-Hydro_N domain-containing protein. (158 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (329 aa)
U3K924_FICALUncharacterized protein. (188 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (482 aa)
KCNK17Potassium channel subfamily K member. (322 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (267 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1176 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1062 aa)
AKAP9A-kinase anchoring protein 9. (2608 aa)
U3K6N9_FICALCation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (316 aa)
STIM1Stromal interaction molecule 1. (607 aa)
U3JW60_FICALSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1973 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (429 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (404 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (96 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
U3JSQ3_FICALIns145_P3_rec domain-containing protein. (93 aa)
RYR3Uncharacterized protein. (4330 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (774 aa)
ASPHAspartate beta-hydroxylase. (776 aa)
KCNK15Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (372 aa)
KCNE1Uncharacterized protein. (127 aa)
MMEMembrane metalloendopeptidase. (698 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
U3JPW9_FICALIon_trans domain-containing protein; Belongs to the potassium channel family. (370 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (747 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2692 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
ABCC9ATP binding cassette subfamily C member 9. (1574 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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