STRINGSTRING
BTC BTC FGFR4 FGFR4 FGF8 FGF8 FLT3 FLT3 FNDC3B FNDC3B KL KL PIK3CA PIK3CA FNDC3A FNDC3A FGF2 FGF2 AREG AREG EREG EREG EPGN EPGN BANK1 BANK1 U3K075_FICAL U3K075_FICAL PDGFRB PDGFRB PIK3CD PIK3CD PIP4K2A PIP4K2A PIK3AP1 PIK3AP1 NRG3 NRG3 FGFR1 FGFR1 EGF EGF PPP4R1 PPP4R1 TRAT1 TRAT1 STRN3 STRN3 SRC SRC NRG1 NRG1 CD86 CD86 EGFR EGFR GAB1 GAB1 U3JNB8_FICAL U3JNB8_FICAL PIK3CB PIK3CB FGF13 FGF13 LOC101807206 LOC101807206 CD28 CD28 KIT KIT PDGFRA PDGFRA FGF18 FGF18 ESR2 ESR2 PIP5K1B PIP5K1B FAM102B FAM102B PPP4R4 PPP4R4 U3JCA6_FICAL U3JCA6_FICAL ERBB2 ERBB2 INSC INSC FGF9 FGF9 GRB2 GRB2 FNBP4 FNBP4 FAM102A FAM102A FGF3 FGF3 FGF4 FGF4 FGF19 FGF19 CD80 CD80 FGF6 FGF6 FGF23 FGF23 FGFR2 FGFR2 U3KLQ5_FICAL U3KLQ5_FICAL LOC101809398 LOC101809398 RHOG-2 RHOG-2 RHOG RHOG U3KJD3_FICAL U3KJD3_FICAL U3KIM8_FICAL U3KIM8_FICAL PDGFA PDGFA FGF22 FGF22 PIK3R2 PIK3R2 PIP4K2B PIP4K2B WDR64 WDR64 ERBB4 ERBB4 RELCH RELCH RAC2 RAC2 PDGFB PDGFB ESR1 ESR1 STRN STRN PIP5K1C PIP5K1C INS INS FGF7 FGF7 FGF20 FGF20 FGF10 FGF10 FGF16 FGF16 LOC101811605 LOC101811605 NRG4 NRG4 KITLG KITLG HGF HGF FRS2 FRS2 MET MET FGFR3 FGFR3 PIK3R1 PIK3R1 PIK3R3 PIK3R3 NRG2 NRG2 CD276 CD276 HBEGF HBEGF KLB KLB FGF1 FGF1 PTPN11 PTPN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTCBetacellulin. (177 aa)
FGFR4Fibroblast growth factor receptor. (803 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
FLT3Fms related tyrosine kinase 3. (992 aa)
FNDC3BFibronectin type III domain containing 3B. (883 aa)
KLKlotho. (967 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3AFibronectin type III domain containing 3A. (1166 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (118 aa)
AREGAmphiregulin. (216 aa)
EREGEpiregulin. (153 aa)
EPGNEpithelial mitogen. (151 aa)
BANK1Uncharacterized protein. (170 aa)
U3K075_FICALDBB domain-containing protein. (382 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1093 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (370 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (793 aa)
NRG3Neuregulin 3. (429 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
EGFEpidermal growth factor. (1255 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (950 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (192 aa)
STRN3Striatin 3. (681 aa)
SRCTyrosine-protein kinase. (539 aa)
NRG1Neuregulin 1. (687 aa)
CD86CD86 molecule. (287 aa)
EGFRReceptor protein-tyrosine kinase. (1164 aa)
GAB1GRB2 associated binding protein 1. (754 aa)
U3JNB8_FICALUncharacterized protein. (1034 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
LOC101807206IGv domain-containing protein. (218 aa)
CD28CD28 molecule. (222 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ESR2Estrogen receptor 2. (568 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (545 aa)
FAM102BFamily with sequence similarity 102 member B. (359 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (842 aa)
U3JCA6_FICALUncharacterized protein. (69 aa)
ERBB2Receptor protein-tyrosine kinase. (1243 aa)
INSCINSC spindle orientation adaptor protein. (487 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FNBP4Formin binding protein 4. (950 aa)
FAM102AFamily with sequence similarity 102 member A. (381 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (164 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
CD80Uncharacterized protein. (306 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (210 aa)
FGFR2Fibroblast growth factor receptor. (918 aa)
U3KLQ5_FICALEGF-like domain-containing protein. (49 aa)
LOC101809398Uncharacterized protein. (191 aa)
RHOG-2Ras homolog family member G. (191 aa)
RHOGUncharacterized protein. (191 aa)
U3KJD3_FICALWD_REPEATS_REGION domain-containing protein. (49 aa)
U3KIM8_FICALNucleoplasmin domain-containing protein. (34 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (101 aa)
PIK3R2Uncharacterized protein. (727 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (366 aa)
WDR64WD repeat domain 64. (959 aa)
ERBB4Receptor protein-tyrosine kinase. (1228 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (845 aa)
RAC2Rac family small GTPase 2. (192 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (251 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
STRNStriatin. (605 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (724 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (177 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (149 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (169 aa)
LOC101811605WRNPLPNID domain-containing protein. (927 aa)
NRG4Neuregulin 4. (116 aa)
KITLGKIT ligand. (234 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (732 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1382 aa)
FGFR3Fibroblast growth factor receptor 3. (653 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R3Uncharacterized protein. (753 aa)
NRG2Neuregulin 2. (570 aa)
CD276CD276 molecule. (309 aa)
HBEGFHeparin binding EGF like growth factor. (206 aa)
KLBKlotho beta. (970 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.