(18 nodes) Terpenoid backbone biosynthesis network (Ficedula albicollis)

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Your Input:
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (333 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (337 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	FNTB	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (410 aa)
	MVD	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (409 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (504 aa)
	FNTA	Farnesyltransferase, CAAX box, alpha. (354 aa)
	IDI1	Nudix hydrolase domain-containing protein. (227 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (366 aa)
	PCYOX1	Prenylcysteine oxidase 1. (495 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (256 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (522 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (220 aa)
	PDSS2	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (377 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (298 aa)

Your Current Organism:

Ficedula albicollis

NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	ACAT2	ENSFALP00000000469	ENSFALP00000012639	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.913
ACAT1	GGPS1	ENSFALP00000000469	ENSFALP00000014134	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.456
ACAT1	HMGCR	ENSFALP00000000469	ENSFALP00000010514	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.567
ACAT1	HMGCS1	ENSFALP00000000469	ENSFALP00000011630	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.989
ACAT1	HMGCS2	ENSFALP00000000469	ENSFALP00000003883	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.990
ACAT1	IDI1	ENSFALP00000000469	ENSFALP00000007292	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Nudix hydrolase domain-containing protein.	0.549
ACAT1	MVD	ENSFALP00000000469	ENSFALP00000003642	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.670
ACAT1	MVK	ENSFALP00000000469	ENSFALP00000009108	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.744
ACAT2	ACAT1	ENSFALP00000012639	ENSFALP00000000469	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.913
ACAT2	GGPS1	ENSFALP00000012639	ENSFALP00000014134	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.456
ACAT2	HMGCR	ENSFALP00000012639	ENSFALP00000010514	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.621
ACAT2	HMGCS1	ENSFALP00000012639	ENSFALP00000011630	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
ACAT2	HMGCS2	ENSFALP00000012639	ENSFALP00000003883	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
ACAT2	IDI1	ENSFALP00000012639	ENSFALP00000007292	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Nudix hydrolase domain-containing protein.	0.631
ACAT2	MVD	ENSFALP00000012639	ENSFALP00000003642	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.670
ACAT2	MVK	ENSFALP00000012639	ENSFALP00000009108	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.746
DHDDS	FNTA	ENSFALP00000000380	ENSFALP00000005335	Alkyl transferase; Belongs to the UPP synthase family.	Farnesyltransferase, CAAX box, alpha.	0.955
DHDDS	FNTB	ENSFALP00000000380	ENSFALP00000001251	Alkyl transferase; Belongs to the UPP synthase family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.942
DHDDS	GGPS1	ENSFALP00000000380	ENSFALP00000014134	Alkyl transferase; Belongs to the UPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.961
DHDDS	HMGCR	ENSFALP00000000380	ENSFALP00000010514	Alkyl transferase; Belongs to the UPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.541