STRINGSTRING
OGDH OGDH GCK GCK GPT2 GPT2 HK2 HK2 ALDOB ALDOB SHMT2 SHMT2 ACAT1 ACAT1 CS CS ACSS1 ACSS1 ACOX1 ACOX1 ACO1 ACO1 FH FH SDHA SDHA ENO4 ENO4 ME1 ME1 PSAT1 PSAT1 AGXT AGXT FBP1 FBP1 FBP2 FBP2 IDH1 IDH1 PHGDH PHGDH RGN RGN LOC101813135 LOC101813135 PDHA1 PDHA1 PCCA PCCA HIBCH HIBCH CAT CAT PRPS2 PRPS2 ENO2 ENO2 TPI1 TPI1 GAPDH GAPDH HAO2 HAO2 ACSS2 ACSS2 DLAT DLAT SDHD SDHD ADH5 ADH5 ALDH6A1 ALDH6A1 LOC101821726 LOC101821726 DLST DLST IDNK IDNK ALDOC ALDOC U3JVH9_FICAL U3JVH9_FICAL GLUD1 GLUD1 OGDHL OGDHL G6PD G6PD PSPH PSPH GCSH GCSH PGD PGD GOT2 GOT2 H6PD H6PD ENO1 ENO1 ACADS ACADS GPI GPI SDSL SDSL ME3 ME3 ESD ESD SUCLA2 SUCLA2 GOT1 GOT1 PGAM1 PGAM1 HK3 HK3 TKT TKT GLYCTK GLYCTK IDH3B IDH3B AMT AMT ADPGK ADPGK MDH2 MDH2 PKM PKM ACOX3 ACOX3 MTHFR MTHFR DLD DLD RPIA RPIA SUCLG1 SUCLG1 IDH3A IDH3A GLDC GLDC TALDO1 TALDO1 HAO1 HAO1 PGK1 PGK1 IDH2 IDH2 PRPS1 PRPS1 ACO2 ACO2 TKFC TKFC ACAT2 ACAT2 HADHA HADHA MCEE MCEE MMUT MMUT ECHS1 ECHS1 CPS1 CPS1 RPE RPE HKDC1 HKDC1 HK1 HK1 PDHB PDHB SUCLG2 SUCLG2 PFKL PFKL GPT GPT EHHADH EHHADH MDH1 MDH1 SHMT1 SHMT1 PGP PGP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OGDHOxoglutarate dehydrogenase. (1020 aa)
GCKPhosphotransferase. (465 aa)
GPT2Glutamic--pyruvic transaminase 2. (545 aa)
HK2Hexokinase 2. (917 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (328 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (337 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (471 aa)
ACSS1Acetyl-coenzyme A synthetase. (516 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (592 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
FHFumarate hydratase. (495 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
ENO4Enolase 4. (594 aa)
ME1Malic enzyme. (567 aa)
PSAT1Phosphoserine aminotransferase. (386 aa)
AGXTSerine--pyruvate aminotransferase. (417 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (339 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (340 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
PHGDHPhosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (435 aa)
RGNRegucalcin. (299 aa)
LOC101813135SGL domain-containing protein. (300 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (399 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (707 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (409 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
PRPS2Phosphoribosyl pyrophosphate synthetase 2. (312 aa)
ENO2Enolase 2. (434 aa)
TPI1Triosephosphate isomerase. (255 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
HAO2Hydroxyacid oxidase 2. (368 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (680 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (108 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (535 aa)
LOC101821726Acetyl-coenzyme A synthetase. (682 aa)
DLSTDihydrolipoamide S-succinyltransferase. (468 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (166 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
U3JVH9_FICALFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (333 aa)
GLUD1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (523 aa)
OGDHLOxoglutarate dehydrogenase like. (1012 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (474 aa)
PSPHPhosphoserine phosphatase. (226 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (139 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
GOT2Aspartate aminotransferase. (393 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (790 aa)
ENO1Enolase 1. (445 aa)
ACADSAcyl-CoA dehydrogenase short chain. (373 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (522 aa)
SDSLSerine dehydratase like. (277 aa)
ME3Malic enzyme. (555 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (253 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (437 aa)
GOT1Aspartate aminotransferase. (374 aa)
PGAM1Uncharacterized protein. (208 aa)
HK3Hexokinase 3. (965 aa)
TKTTransketolase. (617 aa)
GLYCTKGlycerate kinase. (506 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (372 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (356 aa)
ADPGKADP dependent glucokinase. (439 aa)
MDH2Malate dehydrogenase. (341 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (651 aa)
DLDDihydrolipoyl dehydrogenase. (508 aa)
RPIARibose 5-phosphate isomerase A. (226 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (358 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (370 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (937 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
PGK1Phosphoglycerate kinase. (417 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (400 aa)
PRPS1Pribosyltran_N domain-containing protein. (318 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (750 aa)
TKFCTriokinase and FMN cyclase. (582 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (754 aa)
MCEEMethylmalonyl-CoA epimerase. (172 aa)
MMUTMethylmalonyl-CoA mutase. (740 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
CPS1Carbamoyl-phosphate synthase 1. (1508 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (276 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK1Hexokinase 1. (917 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (351 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (406 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (785 aa)
GPTGlutamic--pyruvic transaminase. (485 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (725 aa)
MDH1Malate dehydrogenase. (334 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (482 aa)
PGPUncharacterized protein. (108 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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