STRINGSTRING
ORC6 ORC6 CCNE1 CCNE1 PCNA PCNA CDC6 CDC6 ATM ATM HDAC1 HDAC1 MAD2L1 MAD2L1 WEE1 WEE1 BUB1B BUB1B CCND1 CCND1 ABL1 ABL1 STAG2 STAG2 CDC7 CDC7 CCND2 CCND2 CDC25A CDC25A SKP2 SKP2 MCM3 MCM3 SMC3 SMC3 RAD21 RAD21 CDC14A CDC14A TTK TTK SMC1B SMC1B CCND3 CCND3 ORC3 ORC3 CDKN1A CDKN1A CDC14B CDC14B TFDP1 TFDP1 CDC23 CDC23 CDC16 CDC16 PLK1 PLK1 WEE2 WEE2 U3JNF2_FICAL U3JNF2_FICAL ORC2 ORC2 CREBBP CREBBP CDKN1B CDKN1B BUB3 BUB3 CDC27 CDC27 GADD45G GADD45G E2F5 E2F5 CHEK1 CHEK1 GSK3B GSK3B YWHAB YWHAB CDKN2C CDKN2C ANAPC10 ANAPC10 ORC1 ORC1 CCNE2 CCNE2 ANAPC2 ANAPC2 CDC20 CDC20 RAD21L1 RAD21L1 MCM4 MCM4 PRKDC PRKDC YWHAZ YWHAZ E2F1 E2F1 TGFB3 TGFB3 YWHAQ YWHAQ YWHAE YWHAE TFDP2 TFDP2 ATR ATR E2F4 E2F4 YWHAH YWHAH DBF4 DBF4 MCM2 MCM2 SKP1 SKP1 CDC45 CDC45 CCNA1 CCNA1 RB1 RB1 CHEK2 CHEK2 SMAD2 SMAD2 ANAPC5 ANAPC5 ANAPC4 ANAPC4 ANAPC7 ANAPC7 CDK7 CDK7 MAD2L2 MAD2L2 MDM2 MDM2 CUL1 CUL1 ORC5 ORC5 CDK6 CDK6 CCNH CCNH HDAC2 HDAC2 BUB1 BUB1 ANAPC1 ANAPC1 FZR1 FZR1 LOC101806043 LOC101806043 ANAPC11 ANAPC11 EP300 EP300 RBX1 RBX1 TGFB2 TGFB2 CCNB2 CCNB2 RBL1 RBL1 SMAD3 SMAD3 MCM5 MCM5 U3KFN2_FICAL U3KFN2_FICAL RBL2 RBL2 CDK1 CDK1 PTTG1 PTTG1 STAG1 STAG1 E2F3 E2F3 MCM6 MCM6 ORC4 ORC4 MAD1L1 MAD1L1 SFN SFN CDC26 CDC26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORC6Origin recognition complex subunit 6. (285 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (624 aa)
ATMNon-specific serine/threonine protein kinase. (3066 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (457 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (206 aa)
WEE1WEE1 G2 checkpoint kinase. (433 aa)
BUB1BUncharacterized protein. (1090 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
ABL1Tyrosine-protein kinase. (1127 aa)
STAG2Stromal antigen 2. (1262 aa)
CDC7Cell division cycle 7. (528 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (285 aa)
CDC25ACell division cycle 25A. (473 aa)
SKP2S-phase kinase associated protein 2. (442 aa)
MCM3DNA helicase; Belongs to the MCM family. (827 aa)
SMC3Structural maintenance of chromosomes protein. (1218 aa)
RAD21RAD21 cohesin complex component. (631 aa)
CDC14ACell division cycle 14A. (532 aa)
TTKTTK protein kinase. (880 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (307 aa)
ORC3Origin recognition complex subunit 3. (621 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (147 aa)
CDC14BUncharacterized protein. (461 aa)
TFDP1Transcription factor. (412 aa)
CDC23Cell division cycle 23. (585 aa)
CDC16Cell division cycle 16. (646 aa)
PLK1Polo like kinase 1. (508 aa)
WEE2Wee1-like protein kinase. (560 aa)
U3JNF2_FICALSCD domain-containing protein. (1193 aa)
ORC2Origin recognition complex subunit 2. (467 aa)
CREBBPCREB binding protein. (2320 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
BUB3BUB3 mitotic checkpoint protein. (329 aa)
CDC27Cell division cycle 27. (834 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
E2F5E2F transcription factor 5. (349 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (395 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (167 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (870 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (746 aa)
CDC20Cell division cycle 20. (561 aa)
RAD21L1RAD21 cohesin complex component like 1. (568 aa)
MCM4DNA helicase; Belongs to the MCM family. (813 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3419 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
E2F1E2F transcription factor 1. (418 aa)
TGFB3Transforming growth factor beta 3. (456 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (234 aa)
TFDP2Transcription factor. (441 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2657 aa)
E2F4E2F transcription factor 4. (406 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (247 aa)
DBF4DBF4 zinc finger. (683 aa)
MCM2DNA helicase; Belongs to the MCM family. (885 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CDC45Cell division cycle 45. (572 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (384 aa)
RB1RB transcriptional corepressor 1. (924 aa)
CHEK2Checkpoint kinase 2. (522 aa)
SMAD2Mothers against decapentaplegic homolog. (466 aa)
ANAPC5Anaphase promoting complex subunit 5. (757 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (799 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
MDM2MDM2 proto-oncogene. (308 aa)
CUL1Cullin 1; Belongs to the cullin family. (677 aa)
ORC5Origin recognition complex subunit 5. (447 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CCNHCyclin H; Belongs to the cyclin family. (288 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1066 aa)
ANAPC1Anaphase promoting complex subunit 1. (1785 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
LOC101806043Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (409 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
EP300E1A binding protein p300. (2447 aa)
RBX1Ring-box 1. (81 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (400 aa)
RBL1RB transcriptional corepressor like 1. (963 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
MCM5DNA helicase; Belongs to the MCM family. (735 aa)
U3KFN2_FICALANK_REP_REGION domain-containing protein. (137 aa)
RBL2RB transcriptional corepressor like 2. (1142 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
PTTG1Uncharacterized protein. (191 aa)
STAG1Stromal antigen 1. (1257 aa)
E2F3E2F transcription factor 3. (336 aa)
MCM6DNA helicase; Belongs to the MCM family. (903 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (387 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (717 aa)
SFNStratifin; Belongs to the 14-3-3 family. (246 aa)
CDC26Uncharacterized protein. (29 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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