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FUCA1 FUCA1 PPT1 PPT1 CTSE CTSE ATP6V0A1 ATP6V0A1 NAGLU NAGLU CLN5 CLN5 LOC101806847 LOC101806847 LOC101807047 LOC101807047 U3JDV6_FICAL U3JDV6_FICAL GGA3 GGA3 LAPTM5 LAPTM5 ARSA ARSA LAPTM4A LAPTM4A AP3S1 AP3S1 LGMN LGMN ARSG ARSG CTSB CTSB AP1G1 AP1G1 GBA GBA LOC101821887 LOC101821887 LAMP1 LAMP1 GALNS GALNS AP4B1 AP4B1 CTSL CTSL LITAF LITAF SLC11A1 SLC11A1 GLB1L GLB1L AP1S2 AP1S2 CTSS CTSS CTSA CTSA ATP6V0D2 ATP6V0D2 ABCA2 ABCA2 ATP6V0B ATP6V0B CLTC CLTC LAPTM4B LAPTM4B AP4S1 AP4S1 CTNS CTNS DNASE2B DNASE2B NPC1 NPC1 NPC2 NPC2 ACP2 ACP2 AP3M2 AP3M2 HGSNAT HGSNAT AP1S3 AP1S3 GUSB GUSB AP3M1 AP3M1 SLC17A5 SLC17A5 AP1B1 AP1B1 ATP6V0D1 ATP6V0D1 M6PR M6PR U3JYV1_FICAL U3JYV1_FICAL U3JYX5_FICAL U3JYX5_FICAL LIPA LIPA PLA2G15 PLA2G15 CLTCL1 CLTCL1 CTSC CTSC MFSD8 MFSD8 MANBA MANBA GM2A GM2A TPP1 TPP1 SCARB2 SCARB2 HYAL3 HYAL3 HYAL2 HYAL2 HYAL1 HYAL1 ATP6V0A4 ATP6V0A4 GNPTAB GNPTAB ABCB9 ABCB9 CTSO CTSO ATP6V0A2 ATP6V0A2 HEXA HEXA AP3B2 AP3B2 SPAM1 SPAM1 LOC101808315 LOC101808315 ATP6AP1 ATP6AP1 ARSB ARSB GNS GNS AP3B1 AP3B1 HEXB HEXB ATP6V1H ATP6V1H LOC101814202 LOC101814202 CTSZ CTSZ CTSH CTSH AP3S2 AP3S2 ASAH1 ASAH1 GLA GLA AGA AGA CTSD CTSD AP4E1 AP4E1 NAGA NAGA IGF2R IGF2R IDS IDS GLB1 GLB1 GAA GAA GALC GALC FUCA2 FUCA2 GGA1 GGA1 LOC101815274 LOC101815274 U3KFJ3_FICAL U3KFJ3_FICAL AP1M1 AP1M1 SUMF1 SUMF1 AP3D1 AP3D1 LOC101814633 LOC101814633 LOC101820296 LOC101820296 GNPTG GNPTG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (465 aa)
PPT1Palmitoyl-protein thioesterase 1. (298 aa)
CTSECathepsin E; Belongs to the peptidase A1 family. (394 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (655 aa)
CLN5Uncharacterized protein. (302 aa)
LOC101806847Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (257 aa)
LOC101807047Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (267 aa)
U3JDV6_FICALPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (256 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (750 aa)
LAPTM5Lysosomal protein transmembrane 5. (258 aa)
ARSAArylsulfatase A. (439 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (202 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (190 aa)
LGMNLegumain. (431 aa)
ARSGArylsulfatase G. (532 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (341 aa)
AP1G1AP-1 complex subunit gamma. (816 aa)
GBAGlucosylceramidase. (500 aa)
LOC101821887Glucosylceramidase. (524 aa)
LAMP1Lysosomal associated membrane protein 1. (423 aa)
GALNSGalactosamine (N-acetyl)-6-sulfatase. (514 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (735 aa)
CTSLUncharacterized protein; Belongs to the peptidase C1 family. (337 aa)
LITAFLipopolysaccharide induced TNF factor. (148 aa)
SLC11A1Solute carrier family 11 member 1. (548 aa)
GLB1LGalactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. (654 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (168 aa)
CTSSUncharacterized protein; Belongs to the peptidase C1 family. (328 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (508 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
ABCA2ATP binding cassette subfamily A member 2. (2408 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (265 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1506 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (224 aa)
AP4S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
CTNSCystinosin, lysosomal cystine transporter. (367 aa)
DNASE2BDeoxyribonuclease 2 beta. (362 aa)
NPC1NPC intracellular cholesterol transporter 1. (1279 aa)
NPC2NPC intracellular cholesterol transporter 2. (127 aa)
ACP2Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family. (401 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase. (583 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (169 aa)
GUSBGlucuronidase beta. (659 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (420 aa)
SLC17A5Solute carrier family 17 member 5. (484 aa)
AP1B1AP complex subunit beta. (957 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (277 aa)
U3JYV1_FICALLipase; Belongs to the AB hydrolase superfamily. Lipase family. (405 aa)
U3JYX5_FICALAB hydrolase-1 domain-containing protein. (358 aa)
LIPAAB hydrolase-1 domain-containing protein. (450 aa)
PLA2G15Phospholipase A2 group XV. (380 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1890 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (435 aa)
MFSD8Major facilitator superfamily domain containing 8. (538 aa)
MANBAMannosidase beta. (811 aa)
GM2AGM2 ganglioside activator. (189 aa)
TPP1Tripeptidyl peptidase 1. (509 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (482 aa)
HYAL3Hyaluronidase. (452 aa)
HYAL2Hyaluronidase. (476 aa)
HYAL1Hyaluronidase. (451 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1197 aa)
ABCB9ATP binding cassette subfamily B member 9. (793 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (371 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (850 aa)
HEXAUncharacterized protein. (447 aa)
AP3B2AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1059 aa)
SPAM1Hyaluronidase. (587 aa)
LOC101808315Hyaluronidase. (443 aa)
ATP6AP1Uncharacterized protein. (428 aa)
ARSBArylsulfatase B. (402 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (475 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1070 aa)
HEXBBeta-hexosaminidase. (516 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
LOC101814202Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (405 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (304 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (219 aa)
AP3S2Adaptor related protein complex 3 subunit sigma 2. (239 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (396 aa)
GLAAlpha-galactosidase. (379 aa)
AGAAspartylglucosaminidase. (306 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (396 aa)
AP4E1AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. (1069 aa)
NAGAAlpha-galactosidase. (434 aa)
IGF2RInsulin like growth factor 2 receptor. (2436 aa)
IDSSulfatase domain-containing protein. (503 aa)
GLB1Beta-galactosidase. (637 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (754 aa)
GALCGalactosylceramidase. (667 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (460 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa)
LOC101815274Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (393 aa)
U3KFJ3_FICALUncharacterized protein. (212 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
SUMF1Sulfatase modifying factor 1. (292 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1207 aa)
LOC101814633Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (242 aa)
LOC101820296P-type domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (926 aa)
GNPTGN-acetylglucosamine-1-phosphate transferase subunit gamma. (288 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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