STRINGSTRING
RAF1 RAF1 TCF7L1 TCF7L1 TXN TXN BIRC2 BIRC2 DYNC2H1 DYNC2H1 HSP90B1 HSP90B1 RAB7B RAB7B RAB5C RAB5C PIK3C2A PIK3C2A KLC4 KLC4 MAP2K2 MAP2K2 EXOC7 EXOC7 ARF1 ARF1 LOC101808892 LOC101808892 FADD FADD KPNA4 KPNA4 DYNLT3 DYNLT3 DYNC1I2 DYNC1I2 LOC101810521 LOC101810521 ARPC5L ARPC5L CASP7 CASP7 TAB3 TAB3 MAP2K6 MAP2K6 MYO6 MYO6 DYNC1H1 DYNC1H1 PTPRC PTPRC HSP90AA1 HSP90AA1 ELMO1 ELMO1 KLC1 KLC1 AKT1 AKT1 ARPC5 ARPC5 RHOJ RHOJ GCC2 GCC2 MAPK13 MAPK13 MAPK14 MAPK14 PLEKHM2 PLEKHM2 EXOC5 EXOC5 BAK1 BAK1 ARPC2 ARPC2 CYFIP1 CYFIP1 PIK3CB PIK3CB CASP8 CASP8 U3JNE7_FICAL U3JNE7_FICAL GAPDH GAPDH ELMO2 ELMO2 KPNA1 KPNA1 TIRAP TIRAP ARHGEF26 ARHGEF26 DYNLL2 DYNLL2 RIPK2 RIPK2 RALA RALA TNFRSF1A TNFRSF1A VPS41 VPS41 PFN2 PFN2 MAPK10 MAPK10 VPS39 VPS39 U3JU34_FICAL U3JU34_FICAL NFKBIA NFKBIA VPS18 VPS18 IL18 IL18 U3JUX4_FICAL U3JUX4_FICAL MYL12B MYL12B FOS FOS IKBKB IKBKB MYD88 MYD88 RILP RILP ROCK2 ROCK2 U3JWB1_FICAL U3JWB1_FICAL ABI1 ABI1 PIK3CD PIK3CD M6PR M6PR MLKL MLKL MAPK8 MAPK8 LOC101820432 LOC101820432 DYNLL1 DYNLL1 PAK1 PAK1 TRADD TRADD DYNC1LI2 DYNC1LI2 U3JZ18_FICAL U3JZ18_FICAL MAPK9 MAPK9 SKP1 SKP1 RAB7A RAB7A MAPK1 MAPK1 RPS3 RPS3 LOC101807822 LOC101807822 CXCL8 CXCL8 LOC101808210 LOC101808210 NFKB1 NFKB1 FLNB FLNB PIK3CA PIK3CA KPNA3 KPNA3 CYFIP2 CYFIP2 TNFSF10 TNFSF10 LY96 LY96 RHOA RHOA PIK3C3 PIK3C3 MYL2 MYL2 VPS33A VPS33A NOD1 NOD1 DYNC1LI1 DYNC1LI1 ARPC3 ARPC3 RAB5A RAB5A MYL10 MYL10 PLEKHM1 PLEKHM1 U3K4K5_FICAL U3K4K5_FICAL IL6 IL6 MAPK11 MAPK11 VPS11 VPS11 WASL WASL MAP2K1 MAP2K1 LOC101816877 LOC101816877 DYNC1I1 DYNC1I1 CDC42 CDC42 FBXO22 FBXO22 SNX33 SNX33 SNX18 SNX18 PAK3 PAK3 MAP2K4 MAP2K4 HSP90AB1 HSP90AB1 U3KA53_FICAL U3KA53_FICAL AKT3 AKT3 ACBD3 ACBD3 CASP3 CASP3 EXOC4 EXOC4 PODXL PODXL HRAS HRAS CYTH1 CYTH1 CTNNB1 CTNNB1 LEF1 LEF1 TAB1 TAB1 FYCO1 FYCO1 TRAF6 TRAF6 DYNLRB1 DYNLRB1 DYNLT1 DYNLT1 MYL9 MYL9 DYNC2LI1 DYNC2LI1 CYTH4 CYTH4 CHUK CHUK CSE1L CSE1L ARPC4 ARPC4 BCL2 BCL2 TXN2 TXN2 EXOC2 EXOC2 U3KF52_FICAL U3KF52_FICAL RIPK1 RIPK1 TAB2 TAB2 NCKAP1 NCKAP1 NME9 NME9 MAP2K3 MAP2K3 ARPC1B ARPC1B ARPC1A ARPC1A ACTB ACTB CYTH3 CYTH3 RAC1 RAC1 TLR2 TLR2 TLR5 TLR5 ARF6 ARF6 RHOG RHOG RHOB RHOB LOC101817858 LOC101817858 JUN JUN RHOH RHOH RAB9B RAB9B RAB9A RAB9A LOC101809398 LOC101809398 LOC101812558 LOC101812558
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (667 aa)
TCF7L1Transcription factor 7 like 1. (325 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (111 aa)
BIRC2Uncharacterized protein. (611 aa)
DYNC2H1Uncharacterized protein. (2107 aa)
HSP90B1Heat shock protein 90 beta family member 1. (794 aa)
RAB7BRAB7B, member RAS oncogene family. (203 aa)
RAB5CUncharacterized protein. (216 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1700 aa)
KLC4TPR_REGION domain-containing protein. (633 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (781 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
LOC101808892Non-specific serine/threonine protein kinase. (543 aa)
FADDFas associated via death domain. (227 aa)
KPNA4Importin subunit alpha; Belongs to the importin alpha family. (522 aa)
DYNLT3Dynein light chain Tctex-type 3. (116 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (629 aa)
LOC101810521Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (292 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (80 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (310 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (684 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1299 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4467 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1201 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (728 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
KLC1Uncharacterized protein. (542 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (104 aa)
RHOJRas homolog family member J. (214 aa)
GCC2GRIP and coiled-coil domain containing 2. (1675 aa)
MAPK13Mitogen-activated protein kinase. (367 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (1019 aa)
EXOC5Exocyst complex component 5. (709 aa)
BAK1BCL2 antagonist/killer 1. (213 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (302 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (507 aa)
U3JNE7_FICALUncharacterized protein; Belongs to the peptidase C14A family. (468 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
KPNA1Importin subunit alpha; Belongs to the importin alpha family. (544 aa)
TIRAPTIR domain containing adaptor protein. (237 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (579 aa)
DYNLL2Dynein light chain. (89 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (573 aa)
RALARAS like proto-oncogene A. (206 aa)
TNFRSF1AUncharacterized protein. (429 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (863 aa)
PFN2Profilin; Belongs to the profilin family. (96 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
VPS39VPS39 subunit of HOPS complex. (865 aa)
U3JU34_FICALProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (286 aa)
NFKBIAANK_REP_REGION domain-containing protein. (313 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (996 aa)
IL18Interleukin 18. (207 aa)
U3JUX4_FICALUncharacterized protein. (193 aa)
MYL12BUncharacterized protein. (172 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (371 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (259 aa)
RILPRH2 domain-containing protein. (325 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1411 aa)
U3JWB1_FICALUncharacterized protein. (221 aa)
ABI1Abl interactor 1. (613 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (277 aa)
MLKLMixed lineage kinase domain like pseudokinase. (484 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
LOC101820432Dynein light chain. (89 aa)
DYNLL1Dynein light chain. (94 aa)
PAK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (499 aa)
TRADDTNFRSF1A associated via death domain. (306 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (421 aa)
U3JZ18_FICALUncharacterized protein. (570 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
MAPK1Mitogen-activated protein kinase. (321 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (319 aa)
LOC101807822Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (169 aa)
LOC101808210Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
NFKB1Nuclear factor kappa B subunit 1. (982 aa)
FLNBFilamin B. (2652 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KPNA3Importin subunit alpha; Belongs to the importin alpha family. (497 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (301 aa)
LY96Lymphocyte antigen 96. (155 aa)
RHOARas homolog family member A. (172 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (882 aa)
MYL2Myosin light chain 2. (165 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (539 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (432 aa)
ARPC3Actin related protein 2/3 complex subunit 3. (328 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
MYL10Uncharacterized protein. (165 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1009 aa)
U3K4K5_FICALCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
IL6Interleukin 6. (165 aa)
MAPK11Mitogen-activated protein kinase. (333 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (929 aa)
WASLWASP like actin nucleation promoting factor. (506 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (404 aa)
LOC101816877Interleukin 1 receptor associated kinase 4. (464 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
CDC42Cell division cycle 42. (191 aa)
FBXO22F-box protein 22. (393 aa)
SNX33Sorting nexin. (565 aa)
SNX18Sorting nexin. (559 aa)
PAK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (290 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (396 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (725 aa)
U3KA53_FICALTNFR-Cys domain-containing protein. (228 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ACBD3Acyl-CoA binding domain containing 3. (511 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (282 aa)
EXOC4Uncharacterized protein. (179 aa)
PODXLUncharacterized protein. (567 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CYTH1Cytohesin 1. (416 aa)
CTNNB1Catenin beta 1. (781 aa)
LEF1Lymphoid enhancer binding factor 1. (331 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (427 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1596 aa)
TRAF6TNF receptor-associated factor. (471 aa)
DYNLRB1Dynein light chain roadblock. (96 aa)
DYNLT1Dynein light chain Tctex-type 1. (127 aa)
MYL9Myosin light chain 9. (180 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (355 aa)
CYTH4Cytohesin 4. (407 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (751 aa)
CSE1LChromosome segregation 1 like. (1000 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (167 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TXN2Thioredoxin 2. (141 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (925 aa)
U3KF52_FICALTIR domain-containing protein; Belongs to the Toll-like receptor family. (792 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (705 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (698 aa)
NCKAP1NCK associated protein 1. (1028 aa)
NME9Thioredoxin domain-containing protein. (99 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (371 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ACTBActin beta. (378 aa)
CYTH3Cytohesin 3. (399 aa)
RAC1Rac family small GTPase 1. (192 aa)
TLR2TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
TLR5TIR domain-containing protein; Belongs to the Toll-like receptor family. (862 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RHOGUncharacterized protein. (191 aa)
RHOBRas homolog family member B. (196 aa)
LOC101817858Toll-like receptor. (801 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
RHOHRas homolog family member H. (191 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
LOC101809398Uncharacterized protein. (191 aa)
LOC101812558TIR domain-containing protein. (875 aa)
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
Server load: low (14%) [HD]