node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PMM0153 | PMM0408 | PMM0153 | PMM0408 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | 0.648 |
PMM0153 | ahcY, | PMM0153 | PMM1625 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.434 |
PMM0153 | metA | PMM0153 | PMM0643 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.897 |
PMM0153 | metB | PMM0153 | PMM0409 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | Putative Cystathionine gamma-synthase; Alternative locus ID: PMED4_04521. | 0.648 |
PMM0153 | metH | PMM0153 | PMM0877 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
PMM0153 | metK | PMM0153 | PMM0311 | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.714 |
PMM0408 | PMM0153 | PMM0408 | PMM0153 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | 0.648 |
PMM0408 | ahcY, | PMM0408 | PMM1625 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.916 |
PMM0408 | cysD-2 | PMM0408 | PMM0642 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | 0.938 |
PMM0408 | cysK1 | PMM0408 | PMM0407 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.984 |
PMM0408 | cysK2 | PMM0408 | PMM0123 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.955 |
PMM0408 | metA | PMM0408 | PMM0643 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.945 |
PMM0408 | metB | PMM0408 | PMM0409 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative Cystathionine gamma-synthase; Alternative locus ID: PMED4_04521. | 0.937 |
PMM0408 | metH | PMM0408 | PMM0877 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.975 |
ahcY, | PMM0153 | PMM1625 | PMM0153 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Conserved hypothetical protein; Alternative locus ID: PMED4_01591; Belongs to the methylenetetrahydrofolate reductase family. | 0.434 |
ahcY, | PMM0408 | PMM1625 | PMM0408 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | 0.916 |
ahcY, | cysD-2 | PMM1625 | PMM0642 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | 0.914 |
ahcY, | cysK1 | PMM1625 | PMM0407 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.849 |
ahcY, | cysK2 | PMM1625 | PMM0123 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.847 |
ahcY, | metB | PMM1625 | PMM0409 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Putative Cystathionine gamma-synthase; Alternative locus ID: PMED4_04521. | 0.576 |