STRINGSTRING
gap2 gap2 ABM76928.1 ABM76928.1 pgm pgm rpiA rpiA mipB mipB gpmI gpmI ABM77288.1 ABM77288.1 glgX glgX ABM77448.1 ABM77448.1 tal tal ABM77668.1 ABM77668.1 zwf zwf ABM77715.1 ABM77715.1 prsA prsA ABM77726.1 ABM77726.1 malQ malQ gap3 gap3 ABM77987.1 ABM77987.1 tpi tpi pgi pgi hisZ hisZ pykF pykF rpe rpe glpX glpX glgC glgC gnd gnd pgl pgl glgB glgB ABM78586.1 ABM78586.1 glk glk glgA glgA glmU glmU ABM78904.1 ABM78904.1 ABM78918.1 ABM78918.1 ABM78952.1 ABM78952.1 xylB xylB ABM79074.1 ABM79074.1 ABM79115.1 ABM79115.1 glmM glmM ABM79308.1 ABM79308.1 ABM79309.1 ABM79309.1 glcE glcE glgP glgP glmS glmS tktA tktA nagA nagA eno eno pgk pgk sps sps
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gap2COG57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (376 aa)
ABM76928.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (346 aa)
pgmCOG33 Phosphoglucomutase [Carbohydrate transport and metabolism]. (552 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (238 aa)
mipBPutative fructose-6-phosphate aldolase (FSA); COG176 Transaldolase [Carbohydrate transport and metabolism]. (223 aa)
gpmIPhosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (540 aa)
ABM77288.1COG363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]. (274 aa)
glgXPutative isoamylase; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Belongs to the glycosyl hydrolase 13 family. (704 aa)
ABM77448.1Putative glycolate oxidase subunit glcD; COG277 FAD/FMN-containing dehydrogenases [Energy production and conversion]. (491 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (390 aa)
ABM77668.1COG1543 Uncharacterized conserved protein [Function unknown]; Belongs to the glycosyl hydrolase 57 family. (522 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
ABM77715.1Possible sugar-phosphate nucleotidyl transferase; COG662 Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]. (127 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (337 aa)
ABM77726.1Conserved hypothetical protein. (178 aa)
malQCOG1640 4-alpha-glucanotransferase [Carbohydrate transport and metabolism]. (521 aa)
gap3COG57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (351 aa)
ABM77987.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (283 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (243 aa)
pgiPhosphoglucose isomerase (PGI); COG166 Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Belongs to the GPI family. (536 aa)
hisZPossible Histidyl-tRNA synthetase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa)
pykFCOG469 Pyruvate kinase [Carbohydrate transport and metabolism]; Belongs to the pyruvate kinase family. (605 aa)
rpeCOG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family. (264 aa)
glpXFructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (334 aa)
glgCCOG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (431 aa)
gnd6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa)
pglPutative 6-phosphogluconolactonase (DevB, Pgl); Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (756 aa)
ABM78586.1ROK family protein; COG1940 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]. (304 aa)
glkCOG837 Glucokinase [Carbohydrate transport and metabolism]; Belongs to the bacterial glucokinase family. (353 aa)
glgAPutative ADPglucose--glucosyltransferase (GlgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (499 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (470 aa)
ABM78904.1Glycoside hydrolase family protein; COG366 Glycosidases [Carbohydrate transport and metabolism]. (483 aa)
ABM78918.1Putative neutral invertase-like protein. (488 aa)
ABM78952.1Haloacid dehalogenase/epoxide hydrolase family protein; COG637 Predicted phosphatase/phosphohexomutase [General function prediction only]. (270 aa)
xylBCarbohydrate kinase, FGGY family protein; COG1070 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]. (427 aa)
ABM79074.1Hypothetical protein; COG3588 Fructose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]. (241 aa)
ABM79115.1Hypothetical protein. (60 aa)
glmMPhosphotransferase superclass; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (468 aa)
ABM79308.1Hypothetical protein. (43 aa)
ABM79309.1COG247 Fe-S oxidoreductase [Energy production and conversion]. (507 aa)
glcEPutative glycolate oxidase subunit GlcE; COG277 FAD/FMN-containing dehydrogenases [Energy production and conversion]. (460 aa)
glgPPhosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (841 aa)
glmSGlutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (634 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (669 aa)
nagACOG1820 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]. (400 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
pgkCOG126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. (401 aa)
spsSucrose phosphate synthase; COG438 Glycosyltransferase [Cell envelope biogenesis, outer membrane]. (707 aa)
Your Current Organism:
Prochlorococcus marinus MIT9303
NCBI taxonomy Id: 59922
Other names: P. marinus str. MIT 9303, Prochlorococcus marinus str. MIT 9303, Prochlorococcus sp. MIT 9303, Prochlorococcus sp. MIT9303
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