STRINGSTRING
ABM79219.1 ABM79219.1 folK folK ABM79278.1 ABM79278.1 ABM79311.1 ABM79311.1 tmk tmk nadK-2 nadK-2 ABM79429.1 ABM79429.1 ABM79432.1 ABM79432.1 xylB xylB ABM78857.1 ABM78857.1 ABM78817.1 ABM78817.1 ABM78809.1 ABM78809.1 ABM78778.1 ABM78778.1 ABM78777.1 ABM78777.1 ribF ribF nadK nadK glk glk thrB thrB ABM78586.1 ABM78586.1 proB proB prkB prkB rsbW rsbW ispE ispE ABM78346.1 ABM78346.1 pykF pykF pgi pgi cobU cobU ABM78202.1 ABM78202.1 cysC cysC ABM78152.1 ABM78152.1 tpi tpi ABM78075.1 ABM78075.1 ABM78062.1 ABM78062.1 dgkA dgkA ABM79501.1 ABM79501.1 eno eno pgk pgk coaE coaE ndk ndk ABM79597.1 ABM79597.1 ABM79674.1 ABM79674.1 ABM79676.1 ABM79676.1 ppk ppk sec59 sec59 ABM79751.1 ABM79751.1 nblS nblS ABM76946.1 ABM76946.1 gmk gmk argB argB ABM77492.1 ABM77492.1 ABM76928.1 ABM76928.1 lysC lysC thiL thiL aroK aroK anmK anmK ABM77072.1 ABM77072.1 gpmI gpmI kaiC kaiC pyrH pyrH sasA sasA prsA prsA ABM77734.1 ABM77734.1 phoR phoR ABM77987.1 ABM77987.1 ABM78009.1 ABM78009.1 panC panC ABM79005.1 ABM79005.1 ABM79027.1 ABM79027.1 adk adk ABM79074.1 ABM79074.1 ABM79172.1 ABM79172.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABM79219.1COG642 Signal transduction histidine kinase [Signal transduction mechanisms]. (379 aa)
folKPossible 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; COG801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism]. (248 aa)
ABM79278.1Selenide,water dikinase; COG1252 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]. (730 aa)
ABM79311.1COG3395 Uncharacterized protein conserved in bacteria [Function unknown]. (480 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (216 aa)
nadK-2Predicted inorganic polyphosphate / ATP-NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (315 aa)
ABM79429.1Hypothetical protein. (302 aa)
ABM79432.1Hypothetical protein. (110 aa)
xylBCarbohydrate kinase, FGGY family protein; COG1070 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]. (427 aa)
ABM78857.1Hypothetical protein. (239 aa)
ABM78817.1COG642 Signal transduction histidine kinase [Signal transduction mechanisms]. (496 aa)
ABM78809.1Hypothetical protein. (140 aa)
ABM78778.1Hypothetical protein. (164 aa)
ABM78777.1COG3063 Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]. (233 aa)
ribFPutative riboflavin kinase/FAD synthase; COG196 FAD synthase [Coenzyme metabolism]; Belongs to the ribF family. (310 aa)
nadKPredicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (302 aa)
glkCOG837 Glucokinase [Carbohydrate transport and metabolism]; Belongs to the bacterial glucokinase family. (353 aa)
thrBHomoserine kinase:GHMP kinases putative ATP-binding domain; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa)
ABM78586.1ROK family protein; COG1940 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]. (304 aa)
proBPutative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (361 aa)
prkBCOG3954 Phosphoribulokinase [Energy production and conversion]. (300 aa)
rsbWCOG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]. (164 aa)
ispEPutative 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (CMK); Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (319 aa)
ABM78346.1Hypothetical protein. (66 aa)
pykFCOG469 Pyruvate kinase [Carbohydrate transport and metabolism]; Belongs to the pyruvate kinase family. (605 aa)
pgiPhosphoglucose isomerase (PGI); COG166 Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Belongs to the GPI family. (536 aa)
cobUCOG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase [Coenzyme metabolism]. (186 aa)
ABM78202.1COG4240 Predicted kinase [General function prediction only]. (352 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (227 aa)
ABM78152.1COG642 Signal transduction histidine kinase [Signal transduction mechanisms]. (444 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (243 aa)
ABM78075.1Conserved hypothetical protein. (371 aa)
ABM78062.1COG2187 Uncharacterized protein conserved in bacteria [Function unknown]. (556 aa)
dgkACOG818 Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]. (152 aa)
ABM79501.1Possible kinase; COG661 Predicted unusual protein kinase [General function prediction only]. (559 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
pgkCOG126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. (401 aa)
coaEPutative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (244 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (152 aa)
ABM79597.1COG515 Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms. (444 aa)
ABM79674.1Hypothetical protein. (693 aa)
ABM79676.1Hypothetical protein. (99 aa)
ppkPutative Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (712 aa)
sec59COG170 Dolichol kinase [Lipid metabolism]. (201 aa)
ABM79751.1Possible protein kinase:ABC1 family protein; COG661 Predicted unusual protein kinase [General function prediction only]. (629 aa)
nblSCOG5002 Signal transduction histidine kinase [Signal transduction mechanisms]. (685 aa)
ABM76946.1COG515 Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms. (640 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (192 aa)
argBAspartokinase superfamily:Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (308 aa)
ABM77492.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (342 aa)
ABM76928.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (346 aa)
lysCCOG527 Aspartokinases [Amino acid transport and metabolism]. (595 aa)
thiLPutative thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (327 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
anmKPredicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (379 aa)
ABM77072.1Conserved hypothetical protein. (326 aa)
gpmIPhosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (540 aa)
kaiCPossible circadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. (488 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
sasATwo-component sensor histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (370 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (337 aa)
ABM77734.1Possible kinase; COG661 Predicted unusual protein kinase [General function prediction only]. (564 aa)
phoRTwo-component sensor histidine kinase, phosphate sensing; COG642 Signal transduction histidine kinase [Signal transduction mechanisms]. (361 aa)
ABM77987.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (283 aa)
ABM78009.1Hypothetical protein. (107 aa)
panCPanthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (488 aa)
ABM79005.1COG642 Signal transduction histidine kinase [Signal transduction mechanisms]. (463 aa)
ABM79027.1COG3001 Uncharacterized protein conserved in bacteria [Function unknown]; Belongs to the fructosamine kinase family. (287 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (182 aa)
ABM79074.1Hypothetical protein; COG3588 Fructose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]. (241 aa)
ABM79172.1COG2971 Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]. (320 aa)
Your Current Organism:
Prochlorococcus marinus MIT9303
NCBI taxonomy Id: 59922
Other names: P. marinus str. MIT 9303, Prochlorococcus marinus str. MIT 9303, Prochlorococcus sp. MIT 9303, Prochlorococcus sp. MIT9303
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