STRINGSTRING
met17 met17 aroG aroG speE speE menA menA crtB crtB ABM79361.1 ABM79361.1 kdsA kdsA ABM79185.1 ABM79185.1 ABM79023.1 ABM79023.1 ribH ribH spsE spsE miaA miaA ecm4 ecm4 ribE ribE ctaB ctaB ubiA ubiA hemC hemC cobO cobO ispA ispA uppS uppS ABM77804.1 ABM77804.1 ABM78139.1 ABM78139.1 ubiX ubiX nadA nadA ABM78549.1 ABM78549.1 aroA aroA sds sds thiE thiE ABM78725.1 ABM78725.1 chlG chlG ABM78836.1 ABM78836.1 metB metB ABM78855.1 ABM78855.1 metK metK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
met17COG2873 O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]. (442 aa)
aroGDAHP synthetase class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (360 aa)
speEPutative spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)
menA1,4-dihydroxy-2-naphthoate (DHNA) octaprenyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily. (324 aa)
crtBCOG1562 Phytoene/squalene synthetase [Lipid metabolism]. (313 aa)
ABM79361.1O-acetylserine (thiol)-lyase A; COG31 Cysteine synthase [Amino acid transport and metabolism]; Belongs to the cysteine synthase/cystathionine beta- synthase family. (328 aa)
kdsACOG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Belongs to the KdsA family. (300 aa)
ABM79185.1COG2109 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]. (204 aa)
ABM79023.1COG2109 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]. (402 aa)
ribHPutative 6,7-dimethyl-8-ribityllumazine synthase or riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (165 aa)
spsECOG2089 Sialic acid synthase [Cell envelope biogenesis, outer membrane]. (335 aa)
miaAtRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (299 aa)
ecm4COG435 Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]. (330 aa)
ribECOG307 Riboflavin synthase alpha chain [Coenzyme metabolism]. (220 aa)
ctaBPutative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (333 aa)
ubiAProbable 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family. (297 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (317 aa)
cobOPossible cob(I)alamin adenosyltransferase; COG2109 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]. (230 aa)
ispAPolyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. (306 aa)
uppSUndecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (265 aa)
ABM77804.1MAPEG. (127 aa)
ABM78139.1Hypothetical protein. (77 aa)
ubiXPutative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (202 aa)
nadAQuinolinate synthetase A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (333 aa)
ABM78549.1COG625 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]. (417 aa)
aroAEPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa)
sdsPolyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. (323 aa)
thiEThiamine monophosphate synthase (TMP); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (353 aa)
ABM78725.1Hypothetical protein; COG766 UDP-N-acetylglucosamine enolpyruvyl transferase [Cell envelope biogenesis, outer membrane]. (305 aa)
chlGChlorophyll synthase 33 kD subunit; COG382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]. (336 aa)
ABM78836.1Possible Galanin. (329 aa)
metBCOG626 Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]. (389 aa)
ABM78855.1O-acetylserine (thiol)-lyase A; COG31 Cysteine synthase [Amino acid transport and metabolism]; Belongs to the cysteine synthase/cystathionine beta- synthase family. (328 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (419 aa)
Your Current Organism:
Prochlorococcus marinus MIT9303
NCBI taxonomy Id: 59922
Other names: P. marinus str. MIT 9303, Prochlorococcus marinus str. MIT 9303, Prochlorococcus sp. MIT 9303, Prochlorococcus sp. MIT9303
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.