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| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (886 aa) |
| | EU91_1923 | Hypothetical protein; Alternative locus ID: PGP2_1874; FIG00940617: hypothetical protein. (301 aa) |
| | EU91_1918 | Phage integrase family; Alternative locus ID: PGP2_1869. (389 aa) |
| | EU91_1911 | Exodeoxyribonuclease III; Alternative locus ID: PGP2_1881. (281 aa) |
| | EU91_1890 | Transcription termination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (209 aa) |
| | EU91_1886 | DNA gyrase subunit A; Alternative locus ID: PGP2_0488. (813 aa) |
| | EU91_1882 | DNA polymerasee III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (385 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (967 aa) |
| | EU91_1866 | Aconitate hydratase 2; Alternative locus ID: PGP2_0468; Belongs to the aconitase/IPM isomerase family. (857 aa) |
| | EU91_1863 | Cyanobacteria-specific RpoD-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (339 aa) |
| | aspS | Aspartyl-tRNA synthetase Aspartyl-tRNA(Asn) synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa) |
| | EU91_1843 | Hypothetical protein; Alternative locus ID: PGP2_0445; FIG00940187: hypothetical protein. (175 aa) |
| | EU91_1839 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (460 aa) |
| | rplI | LSU ribosomal protein L9p; Binds to the 23S rRNA. (151 aa) |
| | rplT | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (115 aa) |
| | dnaX | DNA polymerasee III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (587 aa) |
| | rnj | Zn-dependent hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (661 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (679 aa) |
| | EU91_1812 | DNA polymerasee III delta subunit; Alternative locus ID: PGP2_0414. (333 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (913 aa) |
| | infC | Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (190 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (655 aa) |
| | EU91_1795 | Cyanobacteria-specific RpoD-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (333 aa) |
| | EU91_1789 | Single-stranded DNA-binding protein; Alternative locus ID: PGP2_0391. (123 aa) |
| | EU91_1785 | Two component transcriptional regulator; Alternative locus ID: PGP2_0387; winged helix family. (248 aa) |
| | lysS | Lysyl-tRNA synthetase (class II); Alternative locus ID: PGP2_0386; Belongs to the class-II aminoacyl-tRNA synthetase family. (512 aa) |
| | smpB | tmRNA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...] (164 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (249 aa) |
| | EU91_1750 | Ribonuclease D related protein; Alternative locus ID: PGP2_0351. (211 aa) |
| | recF | DNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (370 aa) |
| | recA | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (365 aa) |
| | rplC | LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (206 aa) |
| | rplD | LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel. (210 aa) |
| | rplW | LSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | LSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (287 aa) |
| | EU91_1720 | SSU ribosomal protein S19p (S15e); Alternative locus ID: PGP2_0321; Belongs to the universal ribosomal protein uS19 family. (49 aa) |
| | rplV | LSU ribosomal protein L22p (L17e); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (128 aa) |
| | rpsC | SSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | rplP | LSU ribosomal protein L16p (L10e); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (160 aa) |
| | rpsQ | SSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa) |
| | rplN | LSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (121 aa) |
| | rplX | LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (118 aa) |
| | rplE | LSU ribosomal protein L5p (L11e); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsH | SSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa) |
| | rplF | LSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa) |
| | rplR | LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (122 aa) |
| | rpsE | SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (206 aa) |
| | rplO | LSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (155 aa) |
| | rpsM | SSU ribosomal protein S13p (S18e); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa) |
| | rpsK | SSU ribosomal protein S11p (S14e); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rpoA | DNA-directed RNA polymerasee alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (342 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (269 aa) |
| | rpmE | LSU ribosomal protein L31p; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (85 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (364 aa) |
| | EU91_1682 | Site-specific recombinase; Alternative locus ID: PGP2_0283. (207 aa) |
| | rpsL | SSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | rpsG | SSU ribosomal protein S7p (S5e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (691 aa) |
| | tuf | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa) |
| | rpsJ | SSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (116 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (205 aa) |
| | EU91_1668 | Cytoplasmic axial filament protein CafA and Ribonuclease G Ribonuclease E; Alternative locus ID: PGP2_0269. (602 aa) |
| | infB | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1121 aa) |
| | nusA | Transcription termination protein NusA; Participates in both transcription termination and antitermination. (467 aa) |
| | EU91_1654 | SSU ribosomal protein S20p; Alternative locus ID: PGP2_0255. (67 aa) |
| | rpoB | DNA-directed RNA polymerasee beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1097 aa) |
| | rpoC1 | DNA-directed RNA polymerasee gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (633 aa) |
| | rpoC2 | DNA-directed RNA polymerasee delta (beta'') subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. (1340 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (348 aa) |
| | EU91_1632 | Hypothetical protein; Alternative locus ID: PGP2_0233; FIG005666: putative helicase. (908 aa) |
| | EU91_1629 | RNA binding methyltransferase FtsJ like; Alternative locus ID: PGP2_0230. (270 aa) |
| | rpoZ | DNA-directed RNA polymerasee omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (78 aa) |
| | EU91_1595 | Hypothetical protein; Alternative locus ID: PGP2_0196; FIG00940322: hypothetical protein. (123 aa) |
| | EU91_1523 | Hypothetical protein; Alternative locus ID: PGP2_0124; FIG001583: hypothetical protein; contains S4-like RNA binding domain. (263 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (307 aa) |
| | rplU | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (146 aa) |
| | kaiC | Circadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. (513 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (412 aa) |
| | EU91_1488 | Bacterial histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) |
| | EU91_1465 | 23S rRNA methyltransferase; Alternative locus ID: PGP2_0066. (236 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (385 aa) |
| | EU91_1455 | Cyanobacteria-specific RpoD-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (313 aa) |
| | ffh | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (492 aa) |
| | era | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (303 aa) |
| | pheS | Phenylalanyl-tRNA synthetase alpha chain; Alternative locus ID: PGP2_0035; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (335 aa) |
| | lexA | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (205 aa) |
| | EU91_1424 | Putative phage integrase family; Alternative locus ID: PGP2_0025. (429 aa) |
| | EU91_1420 | Hypothetical protein; Alternative locus ID: PGP2_0021. (418 aa) |
| | EU91_1377 | Ribosomal large subunit pseudouridine synthase F; Alternative locus ID: PGP2_1664; Belongs to the pseudouridine synthase RsuA family. (240 aa) |
| | polA | DNA polymerasee I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (976 aa) |
| | EU91_1319 | Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (88 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (128 aa) |
| | EU91_1275 | Hypothetical protein; Alternative locus ID: PGP2_1562; FIG137771: hypothetical protein. (134 aa) |
| | rpsN | SSU ribosomal protein S14p (S29e); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (100 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (691 aa) |
| | EU91_1213 | Single-stranded DNA-binding protein; Alternative locus ID: PGP2_1827. (141 aa) |
| | priA | Helicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (744 aa) |
| | sigA | Group 2 RNA polymerasee sigma factor RNA polymerasee sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (394 aa) |
| | EU91_1197 | tRNA dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (335 aa) |
| | EU91_1188 | Hypothetical protein; Alternative locus ID: PGP2_1804; FIG00942471: hypothetical protein. (290 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (157 aa) |
| | trmJ | tRNA:Cm32/Um32 methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (250 aa) |
| | EU91_1129 | Ribosomal RNA small subunit methyltransferase D; Alternative locus ID: PGP2_1745. (199 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (865 aa) |
| | EU91_1106 | Putative helix-turn-helix protein; Alternative locus ID: PGP2_1722. (164 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa) |
| | EU91_1087 | Cold-shock DEAD-box protein A; Alternative locus ID: PGP2_1703; Belongs to the DEAD box helicase family. (593 aa) |
| | EU91_1085 | Exodeoxyribonuclease V beta chain; Alternative locus ID: PGP2_1701. (1208 aa) |
| | EU91_1083 | Exodeoxyribonuclease V gamma chain; Alternative locus ID: PGP2_1699. (1060 aa) |
| | EU91_1075 | Two-component response regulator; Alternative locus ID: PGP2_1691. (245 aa) |
| | EU91_1011 | Hypothetical protein; Alternative locus ID: PGP2_1317; FIG002958: hypothetical protein. (58 aa) |
| | EU91_0992 | 3'-to-5' exoribonuclease RNase R; Alternative locus ID: PGP2_1298; Belongs to the RNR ribonuclease family. (744 aa) |
| | EU91_0971 | tRNA (cytosine34-2'-O-)-methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (160 aa) |
| | EU91_0965 | Exoribonuclease II; Alternative locus ID: PGP2_1271. (394 aa) |
| | rpsR | SSU ribosomal protein S18p; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (73 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; Alternative locus ID: PGP2_1268; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (814 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (652 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (274 aa) |
| | EU91_0894 | Error-prone repair protein UmuD; Alternative locus ID: PGP2_1200; Belongs to the peptidase S24 family. (138 aa) |
| | EU91_0893 | Error-prone; Alternative locus ID: PGP2_1199; lesion bypass DNA polymerase V (UmuC). (428 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (677 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (225 aa) |
| | rpsO | SSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | EU91_0883 | 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB LSU rRNA Gm2251; Alternative locus ID: PGP2_1189; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (335 aa) |
| | mrnC | Hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (133 aa) |
| | EU91_0839 | Crp-family regulatory protein; Alternative locus ID: PGP2_1145. (195 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (217 aa) |
| | EU91_0829 | Ribosome-associated endonuclease; Alternative locus ID: PGP2_1135; involved in final steps of 23S rRNA maturation. (306 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (360 aa) |
| | EU91_0790 | GTP-binding protein TypA/BipA; Alternative locus ID: PGP2_1096. (598 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (818 aa) |
| | tsf | Translation elongation factor T; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (218 aa) |
| | EU91_0751 | ATP-dependent DNA ligase LigC; Alternative locus ID: PGP2_1057. (546 aa) |
| | EU91_0750 | Hypothetical protein; Alternative locus ID: PGP2_1056; FIG003033: Helicase domain protein. (828 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (545 aa) |
| | gltX | Glutamyl-tRNA synthetase Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa) |
| | EU91_0642 | Photosystem I subunit III precursor; Alternative locus ID: PGP2_0964; plastocyanin (cyt c553) docking protein (PsaF). (187 aa) |
| | EU91_0640 | Putative secreted protein MPB70 precursor; Alternative locus ID: PGP2_0962. (581 aa) |
| | EU91_0632 | Hypothetical protein; Alternative locus ID: PGP2_0954; FIG00940299: hypothetical protein. (164 aa) |
| | EU91_0624 | Putative Arenavirus glycoprotein; Alternative locus ID: PGP2_0946. (158 aa) |
| | EU91_0616 | AbrB family transciptional regulator; Alternative locus ID: PGP2_0938. (117 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (868 aa) |
| | EU91_0599 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (438 aa) |
| | trmH | tRNA (Guanosine18-2'-O-) -methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (223 aa) |
| | rpsD | SSU ribosomal protein S4p (S9e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (188 aa) |
| | EU91_0531 | Hypothetical protein; Alternative locus ID: PGP2_0853; Hypothetical protein YaeJ with similarity to translation release factor. (142 aa) |
| | mutM | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (293 aa) |
| | EU91_0489 | YrdC/Sua5 family protein; Alternative locus ID: PGP2_0811; required for threonylcarbamoyladenosine (t(6)A) formation in tRNA; Belongs to the SUA5 family. (193 aa) |
| | EU91_0488 | Protein-N(5)-glutamine methyltransferase PrmC; Alternative locus ID: PGP2_0810; methylates polypeptide chain release factors RF1 and RF2. (289 aa) |
| | nrdR | Ribonucleotide reductase transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (159 aa) |
| | EU91_0482 | SSU ribosomal protein S1p; Alternative locus ID: PGP2_0804. (360 aa) |
| | EU91_0473 | ATP-dependent DNA helicase UvrD/PcrA; Alternative locus ID: PGP2_0795. (802 aa) |
| | EU91_0472 | tRNA nucleotidyltransferase; Alternative locus ID: PGP2_0794; A-adding; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (415 aa) |
| | sfsA | Sugar/maltose fermentation stimulation protein; Alternative locus ID: PGP2_0753; Belongs to the SfsA family. (246 aa) |
| | EU91_0417 | Global nitrogen regulatory protein; Alternative locus ID: PGP2_0739; CRP family of transcriptional regulators. (244 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (968 aa) |
| | EU91_0405 | DNA-3-methyladenine glycosylase II; Alternative locus ID: PGP2_0727; Belongs to the DNA glycosylase MPG family. (135 aa) |
| | mutS2 | Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (803 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (203 aa) |
| | rplK | LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa) |
| | rplA | LSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (235 aa) |
| | rplJ | LSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (175 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (239 aa) |
| | EU91_0363 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (354 aa) |
| | EU91_0339 | Two-component response regulator; Alternative locus ID: PGP2_0661. (242 aa) |
| | EU91_0335 | Translation initiation factor SUI1-related protein; Alternative locus ID: PGP2_0657. (103 aa) |
| | EU91_0324 | Hypothetical protein; Alternative locus ID: PGP2_0646; FIG00941193: hypothetical protein. (61 aa) |
| | EU91_0323 | Bacterial regulatory protein; Alternative locus ID: PGP2_0645; LuxR family. (92 aa) |
| | EU91_0311 | RNA-binding region RNP-1 (RNA recognition motif); Alternative locus ID: PGP2_0633. (139 aa) |
| | EU91_0310 | tRNA nucleotidyltransferase; Alternative locus ID: PGP2_0632; CC-adding. (405 aa) |
| | EU91_0303 | Two-component response regulator; Alternative locus ID: PGP2_0625. (248 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (450 aa) |
| | EU91_0297 | Two-component system response regulator; Alternative locus ID: PGP2_0619. (260 aa) |
| | EU91_0245 | ATPase; Alternative locus ID: PGP2_0567. (429 aa) |
| | smc | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1194 aa) |
| | EU91_0219 | Putative RNA methylase family UPF0020; Alternative locus ID: PGP2_0541; Belongs to the methyltransferase superfamily. (374 aa) |
| | EU91_0191 | HNH endonuclease:HNH nuclease; Alternative locus ID: PGP2_0513. (133 aa) |
| | efp | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa) |
| | EU91_0181 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (116 aa) |
| | rsgA | Ribosome small subunit-stimulated GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (305 aa) |
| | EU91_0175 | tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (334 aa) |
| | EU91_0174 | RNA-binding region RNP-1 (RNA recognition motif); Alternative locus ID: PGP2_0496. (167 aa) |
| | EU91_0157 | Modification methylase EcoRV (Adenine-specific methyltransferase EcoRV) (MEcoRV); Alternative locus ID: PGP2_1506. (286 aa) |
| | EU91_0156 | Alternative locus ID: PGP2_1505; Eco Rv Endonuclease Complex With Dna. (250 aa) |
| | EU91_0138 | Hypothetical protein; Alternative locus ID: PGP2_1487; FIG00940386: hypothetical protein. (219 aa) |
| | EU91_0116 | Putative DNA polymerasee III; Alternative locus ID: PGP2_1465; epsilon subunit. (248 aa) |
| | thrS | Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (638 aa) |
| | EU91_0073 | Cyanobacteria-specific RpoD-like sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (307 aa) |
| | EU91_0071 | Hypothetical protein; Alternative locus ID: PGP2_1420; FIG00941040: hypothetical protein. (106 aa) |
| | EU91_0068 | AbrB family transciptional regulator; Alternative locus ID: PGP2_1417. (120 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (465 aa) |
| | EU91_0023 | SSU ribosomal protein S1p; Alternative locus ID: PGP2_1372. (401 aa) |
| | EU91_0007 | Hypothetical protein; Alternative locus ID: PGP2_1851; FIG00942800: hypothetical protein. (129 aa) |
