STRINGSTRING
EU91_1654 EU91_1654 EU91_1744 EU91_1744 recF recF EU91_1732 EU91_1732 rplC rplC rplW rplW rplB rplB EU91_1720 EU91_1720 rpsC rpsC rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsH rpsH rplR rplR rpsE rpsE rplO rplO rpsK rpsK rplQ rplQ rplM rplM rpsI rpsI rpmE rpmE rpsG rpsG rpsJ rpsJ EU91_1673 EU91_1673 EU91_1632 EU91_1632 EU91_1523 EU91_1523 EU91_1517 EU91_1517 rplU rplU kaiC kaiC EU91_1488 EU91_1488 rpsP rpsP EU91_1420 EU91_1420 EU91_1394 EU91_1394 EU91_1279 EU91_1279 rpmH rpmH rpsN rpsN priA priA EU91_1188 EU91_1188 EU91_1113 EU91_1113 recR recR EU91_1073 EU91_1073 EU91_1041 EU91_1041 rpsU rpsU rpmF rpmF rpsR rpsR rpmG rpmG rpmB rpmB psb28 psb28 dnaG dnaG rpsO rpsO nth nth rpsB rpsB thf1 thf1 EU91_0741 EU91_0741 EU91_0685 EU91_0685 EU91_0682 EU91_0682 EU91_0642 EU91_0642 hpf hpf recO recO EU91_0516 EU91_0516 psaE psaE EU91_0494 EU91_0494 EU91_0482 EU91_0482 psbJ psbJ psbL psbL psbF psbF psbK psbK psbI psbI EU91_0399 EU91_0399 rplJ rplJ rplL rplL EU91_0353 EU91_0353 EU91_0245 EU91_0245 EU91_0186 EU91_0186 EU91_0181 EU91_0181 EU91_0048 EU91_0048 EU91_0047 EU91_0047 EU91_0046 EU91_0046 EU91_0045 EU91_0045 EU91_0044 EU91_0044 cbbL cbbL EU91_0042 EU91_0042 EU91_0040 EU91_0040 EU91_0025 EU91_0025 EU91_0023 EU91_0023 EU91_1878 EU91_1878 EU91_1839 EU91_1839 rpmI rpmI EU91_1808 EU91_1808
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EU91_1654SSU ribosomal protein S20p; Alternative locus ID: PGP2_0255. (67 aa)
EU91_1744Photosystem I subunit II (PsaD); Alternative locus ID: PGP2_0345. (140 aa)
recFDNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (370 aa)
EU91_1732Neurosporene desaturase; Alternative locus ID: PGP2_0333. (501 aa)
rplCLSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (206 aa)
rplWLSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplBLSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (287 aa)
EU91_1720SSU ribosomal protein S19p (S15e); Alternative locus ID: PGP2_0321; Belongs to the universal ribosomal protein uS19 family. (49 aa)
rpsCSSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (243 aa)
rpmCLSU ribosomal protein L29p (L35e); Alternative locus ID: PGP2_0317; Belongs to the universal ribosomal protein uL29 family. (72 aa)
rpsQSSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplNLSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (121 aa)
rplXLSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (118 aa)
rplELSU ribosomal protein L5p (L11e); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsHSSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rplRLSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (122 aa)
rpsESSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (206 aa)
rplOLSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (155 aa)
rpsKSSU ribosomal protein S11p (S14e); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa)
rplQLSU ribosomal protein L17p; Alternative locus ID: PGP2_0302. (116 aa)
rplMLSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (143 aa)
rpsISSU ribosomal protein S9p (S16e); Alternative locus ID: PGP2_0299; Belongs to the universal ribosomal protein uS9 family. (136 aa)
rpmELSU ribosomal protein L31p; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (85 aa)
rpsGSSU ribosomal protein S7p (S5e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsJSSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (116 aa)
EU91_1673Uncharacterized protein; Alternative locus ID: PGP2_0274; similar to the N-terminal domain of Lon protease. (218 aa)
EU91_1632Hypothetical protein; Alternative locus ID: PGP2_0233; FIG005666: putative helicase. (908 aa)
EU91_1523Hypothetical protein; Alternative locus ID: PGP2_0124; FIG001583: hypothetical protein; contains S4-like RNA binding domain. (263 aa)
EU91_1517Putative lumenal protein; Alternative locus ID: PGP2_0118; contains 8 pentapeptide repeats, sll0577 homolog. (186 aa)
rplULSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (146 aa)
kaiCCircadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. (513 aa)
EU91_1488Bacterial histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
rpsPSSU ribosomal protein S16p; Alternative locus ID: PGP2_0051; Belongs to the bacterial ribosomal protein bS16 family. (121 aa)
EU91_1420Hypothetical protein; Alternative locus ID: PGP2_0021. (418 aa)
EU91_1394Cytochrome b559 beta chain (PsbF); Alternative locus ID: PGP2_1681. (98 aa)
EU91_1279Chorismate mutase II; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (127 aa)
rpmHLSU ribosomal protein L34p; Alternative locus ID: PGP2_1564; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
rpsNSSU ribosomal protein S14p (S29e); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (100 aa)
priAHelicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (744 aa)
EU91_1188Hypothetical protein; Alternative locus ID: PGP2_1804; FIG00942471: hypothetical protein. (290 aa)
EU91_1113Ferredoxin-NADP(+) reductase; Alternative locus ID: PGP2_1729. (380 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
EU91_1073Carotenoid cis-trans isomerase; Alternative locus ID: PGP2_1689. (514 aa)
EU91_1041ATP/GTP-binding site motif A; Alternative locus ID: PGP2_1347. (198 aa)
rpsUSSU ribosomal protein S21p; Alternative locus ID: PGP2_1345; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
rpmFLSU ribosomal protein L32p; Alternative locus ID: PGP2_1292; Belongs to the bacterial ribosomal protein bL32 family. (56 aa)
rpsRSSU ribosomal protein S18p; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (73 aa)
rpmGLSU ribosomal protein L33p; Alternative locus ID: PGP2_1269; Belongs to the bacterial ribosomal protein bL33 family. (64 aa)
rpmBLSU ribosomal protein L28p; Alternative locus ID: PGP2_1236; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
psb28Photosystem II 13 kDa protein Psb28 (PsbW); Alternative locus ID: PGP2_1211; Belongs to the Psb28 family. (117 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (677 aa)
rpsOSSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (217 aa)
rpsBSSU ribosomal protein S2p (SAe); Alternative locus ID: PGP2_1087; Belongs to the universal ribosomal protein uS2 family. (234 aa)
thf1Hypothetical protein; May be involved in photosynthetic membrane biogenesis. (196 aa)
EU91_0741Cytochrome C553 (soluble cytochrome f); Alternative locus ID: PGP2_1047. (123 aa)
EU91_0685Ribonucleotide reductase of class II (coenzyme B12-dependent); Alternative locus ID: PGP2_0991. (777 aa)
EU91_0682Hypothetical protein; Alternative locus ID: PGP2_0988; FIG022979: MoxR-like ATPase. (298 aa)
EU91_0642Photosystem I subunit III precursor; Alternative locus ID: PGP2_0964; plastocyanin (cyt c553) docking protein (PsaF). (187 aa)
hpfRibosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (194 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (261 aa)
EU91_0516Phytoene dehydrogenase; Alternative locus ID: PGP2_0838. (509 aa)
psaEPhotosystem I subunit IV (PsaE); Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase; Belongs to the PsaE family. (69 aa)
EU91_0494Putative dNTP triphosphohydrolase; Alternative locus ID: PGP2_0816; putative. (418 aa)
EU91_0482SSU ribosomal protein S1p; Alternative locus ID: PGP2_0804. (360 aa)
psbJPhotosystem II protein PsbJ; One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. (65 aa)
psbLPhotosystem II protein PsbL; One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization. (39 aa)
psbFCytochrome b559 beta chain (PsbF); This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. Belongs to the PsbE/PsbF family. (48 aa)
psbKPhotosystem II protein PsbK; One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. (46 aa)
psbIPhotosystem II protein PsbI; One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light- driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. (42 aa)
EU91_0399Photosystem II manganese-stabilizing protein (PsbO); Alternative locus ID: PGP2_0721. (264 aa)
rplJLSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (175 aa)
rplLLSU ribosomal protein L7/L12 (P1/P2); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (131 aa)
EU91_0353Diacylglycerol kinase; Alternative locus ID: PGP2_0675. (139 aa)
EU91_0245ATPase; Alternative locus ID: PGP2_0567. (429 aa)
EU91_0186Peptidyl-prolyl cis-trans isomerase; Alternative locus ID: PGP2_0508. (363 aa)
EU91_0181Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (116 aa)
EU91_0048Putative carboxysome peptide B; Alternative locus ID: PGP2_1397. (73 aa)
EU91_0047Putative carboxysome peptide A; Alternative locus ID: PGP2_1396. (83 aa)
EU91_0046Carboxysome shell protein CsoS3; Alternative locus ID: PGP2_1395. (509 aa)
EU91_0045Carboxysome shell protein CsoS2; Alternative locus ID: PGP2_1394. (772 aa)
EU91_0044Ribulose bisphosphate carboxylase small chain; Alternative locus ID: PGP2_1393. (89 aa)
cbbLRibulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (471 aa)
EU91_0042Carboxysome shell protein CsoS1; Alternative locus ID: PGP2_1391. (92 aa)
EU91_0040Hypothetical protein; Alternative locus ID: PGP2_1389; FIG00940838: hypothetical protein. (256 aa)
EU91_0025Aldehyde decarbonylase; Catalyzes the decarbonylation of fatty aldehydes to alkanes. (242 aa)
EU91_0023SSU ribosomal protein S1p; Alternative locus ID: PGP2_1372. (401 aa)
EU91_1878DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (559 aa)
EU91_1839Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (460 aa)
rpmILSU ribosomal protein L35p; Alternative locus ID: PGP2_0428; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
EU91_1808Putative Photosystem II reaction center Z protein (PsbZ); Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna. (65 aa)
Your Current Organism:
Prochlorococcus marinus GP2
NCBI taxonomy Id: 59925
Other names: P. marinus str. GP2, Prochlorococcus marinus str. GP2, Prochlorococcus marinus str. RCC296, Prochlorococcus sp. GP2, Prochlorococcus sp. RCC296
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