STRINGSTRING
EU91_0023 EU91_0023 rsgA rsgA efp efp rimO rimO EU91_0482 EU91_0482 recO recO EU91_1789 EU91_1789 EU91_0751 EU91_0751 recG recG EU91_1845 EU91_1845 aspS aspS EU91_1668 EU91_1668 rpsL rpsL rpsQ rpsQ rplB rplB lysS lysS ruvA ruvA pheT pheT EU91_0965 EU91_0965 EU91_0992 EU91_0992 EU91_1213 EU91_1213 pnp pnp EU91_1319 EU91_1319 nusA nusA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EU91_0023SSU ribosomal protein S1p; Alternative locus ID: PGP2_1372. (401 aa)
rsgARibosome small subunit-stimulated GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (305 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
rimORibosomal protein S12p Asp88 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (454 aa)
EU91_0482SSU ribosomal protein S1p; Alternative locus ID: PGP2_0804. (360 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (261 aa)
EU91_1789Single-stranded DNA-binding protein; Alternative locus ID: PGP2_0391. (123 aa)
EU91_0751ATP-dependent DNA ligase LigC; Alternative locus ID: PGP2_1057. (546 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (818 aa)
EU91_1845ATP-dependent DNA ligase; Alternative locus ID: PGP2_0447. (442 aa)
aspSAspartyl-tRNA synthetase Aspartyl-tRNA(Asn) synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa)
EU91_1668Cytoplasmic axial filament protein CafA and Ribonuclease G Ribonuclease E; Alternative locus ID: PGP2_0269. (602 aa)
rpsLSSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
rpsQSSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplBLSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (287 aa)
lysSLysyl-tRNA synthetase (class II); Alternative locus ID: PGP2_0386; Belongs to the class-II aminoacyl-tRNA synthetase family. (512 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (225 aa)
pheTPhenylalanyl-tRNA synthetase beta chain; Alternative locus ID: PGP2_1268; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (814 aa)
EU91_0965Exoribonuclease II; Alternative locus ID: PGP2_1271. (394 aa)
EU91_09923'-to-5' exoribonuclease RNase R; Alternative locus ID: PGP2_1298; Belongs to the RNR ribonuclease family. (744 aa)
EU91_1213Single-stranded DNA-binding protein; Alternative locus ID: PGP2_1827. (141 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (691 aa)
EU91_1319Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (88 aa)
nusATranscription termination protein NusA; Participates in both transcription termination and antitermination. (467 aa)
Your Current Organism:
Prochlorococcus marinus GP2
NCBI taxonomy Id: 59925
Other names: P. marinus str. GP2, Prochlorococcus marinus str. GP2, Prochlorococcus marinus str. RCC296, Prochlorococcus sp. GP2, Prochlorococcus sp. RCC296
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.