(93 nodes) Pyruvate metabolism network (Fibroporia radiculosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FIBRA_00356	Uncharacterized protein. (562 aa)
	FIBRA_00290	Pyruvate kinase; Belongs to the pyruvate kinase family. (1300 aa)
	FIBRA_00048	Malic enzyme. (579 aa)
	FIBRA_09059	F-box domain-containing protein. (508 aa)
	FIBRA_07870	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (431 aa)
	FIBRA_07808	Uncharacterized protein. (649 aa)
	FIBRA_07064	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (414 aa)
	FIBRA_06810	Epimerase domain-containing protein. (360 aa)
	FIBRA_06430	Epimerase domain-containing protein. (336 aa)
	FIBRA_06418	Epimerase domain-containing protein. (338 aa)
	FIBRA_05882	FMN hydroxy acid dehydrogenase domain-containing protein. (535 aa)
	FIBRA_05697	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
	FIBRA_03776	Aldedh domain-containing protein. (533 aa)
	FIBRA_03320	Uncharacterized protein. (487 aa)
	FIBRA_03249	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (367 aa)
	FIBRA_02973	FAD-binding PCMH-type domain-containing protein. (1003 aa)
	FIBRA_02421	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa)
	FIBRA_02108	Probable acetate kinase. (455 aa)
	FIBRA_01514	F-box domain-containing protein. (521 aa)
	FIBRA_01389	Acetyl-coenzyme A synthetase. (643 aa)
	FIBRA_00984	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (423 aa)
	FIBRA_08870	Dihydrolipoyl dehydrogenase. (506 aa)
	FIBRA_08772	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (503 aa)
	FIBRA_07672	Uncharacterized protein. (136 aa)
	FIBRA_06028	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (155 aa)
	FIBRA_05134	Aldedh domain-containing protein. (37 aa)
	FIBRA_05052	Lactamase_B domain-containing protein. (280 aa)
	FIBRA_04392	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (462 aa)
	FIBRA_04323	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
	FIBRA_03777	AB hydrolase-1 domain-containing protein. (519 aa)
	FIBRA_03568	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (231 aa)
	FIBRA_02556	F-box domain-containing protein. (648 aa)
	FIBRA_01257	Uncharacterized protein. (502 aa)
	FIBRA_00679	Uncharacterized protein. (676 aa)
	FIBRA_09010	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	FIBRA_08834	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (325 aa)
	FIBRA_08616	Uncharacterized protein. (527 aa)
	FIBRA_08147	Malate dehydrogenase. (354 aa)
	FIBRA_07827	Epimerase domain-containing protein. (338 aa)
	FIBRA_07558	Uncharacterized protein. (444 aa)
	FIBRA_07236	Uncharacterized protein. (306 aa)
	FIBRA_07172	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (487 aa)
	FIBRA_06433	Epimerase domain-containing protein. (491 aa)
	FIBRA_06416	Epimerase domain-containing protein. (340 aa)
	FIBRA_06218	DJ-1_PfpI domain-containing protein. (224 aa)
	FIBRA_05364	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (336 aa)
	FIBRA_05089	Acylphosphatase. (58 aa)
	FIBRA_04763	Uncharacterized protein. (461 aa)
	FIBRA_04382	Uncharacterized protein. (495 aa)
	FIBRA_03902	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (722 aa)
	FIBRA_03538	Uncharacterized protein. (388 aa)
	FIBRA_03147	Uncharacterized protein. (541 aa)
	FIBRA_02950	Uncharacterized protein. (518 aa)
	FIBRA_02821	Uncharacterized protein. (563 aa)
	FIBRA_02681	Malic enzyme. (390 aa)
	FIBRA_02014	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (398 aa)
	FIBRA_01715	Epimerase domain-containing protein. (369 aa)
	FIBRA_00713	Bms1-type G domain-containing protein. (781 aa)
	FIBRA_08600	Uncharacterized protein. (503 aa)
	FIBRA_08013	BLACT_WH domain-containing protein. (237 aa)
	FIBRA_06417	Epimerase domain-containing protein. (332 aa)
	FIBRA_06382	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (463 aa)
	FIBRA_04126	FMN hydroxy acid dehydrogenase domain-containing protein. (442 aa)
	FIBRA_03816	Uncharacterized protein. (1106 aa)
	FIBRA_03539	Zn(2)-C6 fungal-type domain-containing protein. (301 aa)
	FIBRA_03238	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (517 aa)
	FIBRA_02941	Uncharacterized protein. (469 aa)
	FIBRA_02564	Uncharacterized protein. (384 aa)
	FIBRA_02559	Uncharacterized protein. (459 aa)
	FIBRA_01950	zf-C3HC4 domain-containing protein. (346 aa)
	FIBRA_01757	Uncharacterized protein; Belongs to the cytochrome b5 family. (495 aa)
	FIBRA_01255	Uncharacterized protein. (505 aa)
	FIBRA_08997	Uncharacterized protein. (326 aa)
	FIBRA_08610	Uncharacterized protein. (512 aa)
	FIBRA_08234	Uncharacterized protein. (462 aa)
	FIBRA_08229	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (499 aa)
	FIBRA_07826	Epimerase domain-containing protein. (337 aa)
	FIBRA_07036	Uncharacterized protein. (652 aa)
	FIBRA_06790	FAD-binding PCMH-type domain-containing protein. (507 aa)
	FIBRA_06479	Lactamase_B domain-containing protein. (338 aa)
	FIBRA_06415	Epimerase domain-containing protein. (342 aa)
	FIBRA_06029	VOC domain-containing protein. (150 aa)
	FIBRA_05300	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (370 aa)
	FIBRA_04970	FAD-binding PCMH-type domain-containing protein. (602 aa)
	FIBRA_04814	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	FIBRA_03959	Epimerase domain-containing protein. (342 aa)
	FIBRA_03865	Uncharacterized protein. (470 aa)
	FIBRA_03638	Malic enzyme. (572 aa)
	FIBRA_02949	Uncharacterized protein. (503 aa)
	FIBRA_02778	Uncharacterized protein. (2238 aa)
	FIBRA_02680	Malic domain-containing protein. (142 aa)
	FIBRA_02537	Pyruvate carboxyltransferase domain-containing protein. (801 aa)
	FIBRA_01080	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (537 aa)

Your Current Organism:

Fibroporia radiculosa

NCBI taxonomy Id: 599839
Other names: Antrodia radiculosa, F. radiculosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FIBRA_00048	FIBRA_00290	J7S5J5	J7SC03	Malic enzyme.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.755
FIBRA_00048	FIBRA_00679	J7S5J5	J4HS04	Malic enzyme.	Uncharacterized protein.	0.735
FIBRA_00048	FIBRA_00984	J7S5J5	J4I886	Malic enzyme.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.485
FIBRA_00048	FIBRA_01255	J7S5J5	J4GJP7	Malic enzyme.	Uncharacterized protein.	0.730
FIBRA_00048	FIBRA_01257	J7S5J5	J4HT09	Malic enzyme.	Uncharacterized protein.	0.730
FIBRA_00048	FIBRA_01389	J7S5J5	J4I8G5	Malic enzyme.	Acetyl-coenzyme A synthetase.	0.652
FIBRA_00048	FIBRA_01757	J7S5J5	J4GL94	Malic enzyme.	Uncharacterized protein; Belongs to the cytochrome b5 family.	0.775
FIBRA_00048	FIBRA_01950	J7S5J5	J4GLY2	Malic enzyme.	zf-C3HC4 domain-containing protein.	0.654
FIBRA_00048	FIBRA_02014	J7S5J5	J4H1L6	Malic enzyme.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.761
FIBRA_00048	FIBRA_02421	J7S5J5	J4I919	Malic enzyme.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.796
FIBRA_00048	FIBRA_02537	J7S5J5	J4G1T6	Malic enzyme.	Pyruvate carboxyltransferase domain-containing protein.	0.702
FIBRA_00048	FIBRA_02680	J7S5J5	J4G2A8	Malic enzyme.	Malic domain-containing protein.	0.558
FIBRA_00048	FIBRA_02681	J7S5J5	J4H1Z7	Malic enzyme.	Malic enzyme.	0.541
FIBRA_00048	FIBRA_02778	J7S5J5	J4G2Q4	Malic enzyme.	Uncharacterized protein.	0.652
FIBRA_00048	FIBRA_02821	J7S5J5	J4H224	Malic enzyme.	Uncharacterized protein.	0.775
FIBRA_00048	FIBRA_02941	J7S5J5	J4GN74	Malic enzyme.	Uncharacterized protein.	0.828
FIBRA_00048	FIBRA_02949	J7S5J5	J4G3K4	Malic enzyme.	Uncharacterized protein.	0.775
FIBRA_00048	FIBRA_02950	J7S5J5	J4H249	Malic enzyme.	Uncharacterized protein.	0.775
FIBRA_00048	FIBRA_02973	J7S5J5	J4I9C6	Malic enzyme.	FAD-binding PCMH-type domain-containing protein.	0.679
FIBRA_00048	FIBRA_03568	J7S5J5	J4HW23	Malic enzyme.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.551