(53 nodes) Mixed, incl. Histone methylation, and Structural constituent of chromatin network (Penicillium solitum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6Q3B8	SET domain-containing protein. (382 aa)
	A0A1V6Q728	AB hydrolase-1 domain-containing protein. (295 aa)
	A0A1V6Q7E8	Uncharacterized protein. (352 aa)
	A0A1V6Q9M7	Uncharacterized protein. (1494 aa)
	A0A1V6QAP7	SHNi-TPR domain-containing protein. (450 aa)
	A0A1V6QCF9	SET domain-containing protein. (662 aa)
	A0A1V6QD05	Uncharacterized protein. (837 aa)
	A0A1V6QMD7	Uncharacterized protein. (495 aa)
	A0A1V6QQ45	Histone H3; Belongs to the histone H3 family. (136 aa)
	A0A1V6QQS5	Histone H2B; Belongs to the histone H2B family. (141 aa)
	A0A1V6QQW8	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A1V6QRL8	Histone H2A; Belongs to the histone H2A family. (132 aa)
	A0A1V6QSQ0	Uncharacterized protein. (814 aa)
	A0A1V6QSV7	Uncharacterized protein. (175 aa)
	A0A1V6QTY5	Uncharacterized protein. (1507 aa)
	A0A1V6QTY9	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (356 aa)
	A0A1V6QU08	WD_REPEATS_REGION domain-containing protein. (443 aa)
	A0A1V6QUG2	SET domain-containing protein. (131 aa)
	A0A1V6QUR1	WD_REPEATS_REGION domain-containing protein. (482 aa)
	A0A1V6QUZ0	H15 domain-containing protein. (218 aa)
	A0A1V6QVB7	Uncharacterized protein. (92 aa)
	A0A1V6QVK7	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (503 aa)
	A0A1V6QVP4	Uncharacterized protein. (794 aa)
	A0A1V6QW76	DUF2236 domain-containing protein. (458 aa)
	A0A1V6QW90	Histone H2A; Belongs to the histone H2A family. (139 aa)
	A0A1V6QWI7	PHD-type domain-containing protein. (837 aa)
	A0A1V6QWY2	Uncharacterized protein. (316 aa)
	A0A1V6QY51	WD_REPEATS_REGION domain-containing protein. (1109 aa)
	A0A1V6QZL4	Uncharacterized protein. (381 aa)
	A0A1V6R0J0	PHD-type domain-containing protein. (846 aa)
	A0A1V6R0R3	SET domain-containing protein. (456 aa)
	A0A1V6R197	Uncharacterized protein. (1393 aa)
	A0A1V6R343	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (884 aa)
	A0A1V6R360	Chromo domain-containing protein. (238 aa)
	A0A1V6R3Q1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
	A0A1V6R3R2	SET domain-containing protein. (617 aa)
	A0A1V6R432	Helo_like_N domain-containing protein. (382 aa)
	A0A1V6R7E7	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1210 aa)
	A0A1V6R7H1	Chromo domain-containing protein. (1348 aa)
	A0A1V6R861	Histone acetyltransferase. (528 aa)
	A0A1V6R894	SPRY domain-containing protein. (596 aa)
	A0A1V6R9U0	Uncharacterized protein. (1016 aa)
	A0A1V6RB91	Histone domain-containing protein. (167 aa)
	A0A1V6RC19	Uncharacterized protein. (82 aa)
	A0A1V6RCH7	WD_REPEATS_REGION domain-containing protein. (513 aa)
	A0A1V6RDC5	Uncharacterized protein. (500 aa)
	A0A1V6RI84	Uncharacterized protein. (295 aa)
	A0A1V6RIS9	SET domain-containing protein. (435 aa)
	A0A1V6RJ76	Uncharacterized protein. (169 aa)
	A0A1V6RJD9	Uncharacterized protein. (1105 aa)
	A0A1V6RKU8	SET domain-containing protein. (351 aa)
	A0A1V6RPG1	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A1V6RRC1	PHD-type domain-containing protein. (851 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6Q3B8	A0A1V6Q728	SET domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.630
A0A1V6Q3B8	A0A1V6QCF9	SET domain-containing protein.	SET domain-containing protein.	0.694
A0A1V6Q3B8	A0A1V6QMD7	SET domain-containing protein.	Uncharacterized protein.	0.499
A0A1V6Q3B8	A0A1V6QQ45	SET domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.681
A0A1V6Q3B8	A0A1V6QQS5	SET domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.705
A0A1V6Q3B8	A0A1V6QQW8	SET domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.704
A0A1V6Q3B8	A0A1V6QRL8	SET domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.680
A0A1V6Q3B8	A0A1V6QSQ0	SET domain-containing protein.	Uncharacterized protein.	0.499
A0A1V6Q3B8	A0A1V6QU08	SET domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.777
A0A1V6Q3B8	A0A1V6QUG2	SET domain-containing protein.	SET domain-containing protein.	0.514
A0A1V6Q3B8	A0A1V6QUR1	SET domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.736
A0A1V6Q3B8	A0A1V6QVB7	SET domain-containing protein.	Uncharacterized protein.	0.751
A0A1V6Q3B8	A0A1V6QVP4	SET domain-containing protein.	Uncharacterized protein.	0.640
A0A1V6Q3B8	A0A1V6QW76	SET domain-containing protein.	DUF2236 domain-containing protein.	0.630
A0A1V6Q3B8	A0A1V6QW90	SET domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.670
A0A1V6Q3B8	A0A1V6QWI7	SET domain-containing protein.	PHD-type domain-containing protein.	0.585
A0A1V6Q3B8	A0A1V6QWY2	SET domain-containing protein.	Uncharacterized protein.	0.585
A0A1V6Q3B8	A0A1V6R0R3	SET domain-containing protein.	SET domain-containing protein.	0.514
A0A1V6Q3B8	A0A1V6R197	SET domain-containing protein.	Uncharacterized protein.	0.714
A0A1V6Q3B8	A0A1V6R343	SET domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.699

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