(14 nodes) MAPK cascade, and MAP kinase phosphatase activity network (Penicillium solitum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6QQY6	Protein kinase domain-containing protein. (551 aa)
	A0A1V6QRY1	Uncharacterized protein. (893 aa)
	A0A1V6QU64	Protein kinase domain-containing protein. (622 aa)
	A0A1V6QUE6	Protein kinase domain-containing protein. (363 aa)
	A0A1V6QUI8	MAP kinase kinase kinase. (1343 aa)
	A0A1V6QXU5	Uncharacterized protein. (887 aa)
	A0A1V6R7E5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (494 aa)
	A0A1V6RD59	Protein kinase domain-containing protein. (1613 aa)
	A0A1V6REE1	Uncharacterized protein. (429 aa)
	A0A1V6RHV4	Uncharacterized protein. (711 aa)
	A0A1V6RIW4	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (291 aa)
	A0A1V6RK47	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (422 aa)
	A0A1V6RKQ3	Mitogen-activated protein kinase. (508 aa)
	A0A1V6RQ48	PPM-type phosphatase domain-containing protein. (579 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6QQY6	A0A1V6QRY1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.994
A0A1V6QQY6	A0A1V6QU64	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.865
A0A1V6QQY6	A0A1V6QUE6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.864
A0A1V6QQY6	A0A1V6QUI8	Protein kinase domain-containing protein.	MAP kinase kinase kinase.	0.910
A0A1V6QQY6	A0A1V6QXU5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.570
A0A1V6QQY6	A0A1V6R7E5	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.682
A0A1V6QQY6	A0A1V6RD59	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.956
A0A1V6QQY6	A0A1V6REE1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.552
A0A1V6QQY6	A0A1V6RHV4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.506
A0A1V6QQY6	A0A1V6RIW4	Protein kinase domain-containing protein.	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.	0.903
A0A1V6QQY6	A0A1V6RK47	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.871
A0A1V6QQY6	A0A1V6RKQ3	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.865
A0A1V6QQY6	A0A1V6RQ48	Protein kinase domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.568
A0A1V6QRY1	A0A1V6QQY6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.994
A0A1V6QRY1	A0A1V6QU64	Uncharacterized protein.	Protein kinase domain-containing protein.	0.981
A0A1V6QRY1	A0A1V6QUE6	Uncharacterized protein.	Protein kinase domain-containing protein.	0.693
A0A1V6QRY1	A0A1V6QUI8	Uncharacterized protein.	MAP kinase kinase kinase.	0.840
A0A1V6QRY1	A0A1V6R7E5	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.952
A0A1V6QRY1	A0A1V6RD59	Uncharacterized protein.	Protein kinase domain-containing protein.	0.509
A0A1V6QRY1	A0A1V6RHV4	Uncharacterized protein.	Uncharacterized protein.	0.465

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