(30 nodes) Endoplasmic reticulum organization network (Penicillium solitum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6QRR8	Uncharacterized protein. (1518 aa)
	A0A1V6RRZ2	Uncharacterized protein. (736 aa)
	A0A1V6RQV3	Uncharacterized protein. (751 aa)
	A0A1V6RPW2	Zinc_ribbon_10 domain-containing protein. (394 aa)
	A0A1V6QQM6	Uncharacterized protein. (1234 aa)
	A0A1V6QPZ2	Uncharacterized protein. (629 aa)
	A0A1V6QHX5	Uncharacterized protein. (344 aa)
	A0A1V6QFI0	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (267 aa)
	A0A1V6QDV9	MSP domain-containing protein. (274 aa)
	A0A1V6R6V3	Uncharacterized protein. (374 aa)
	A0A1V6R5Y5	Uncharacterized protein. (350 aa)
	A0A1V6R598	Uncharacterized protein. (1221 aa)
	A0A1V6R4H7	Uncharacterized protein. (634 aa)
	A0A1V6QXL7	Uncharacterized protein. (1031 aa)
	A0A1V6R3C4	Uncharacterized protein. (381 aa)
	A0A1V6R2K7	Uncharacterized protein. (177 aa)
	A0A1V6R271	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1038 aa)
	A0A1V6R170	Protein YOP1. (330 aa)
	GET1	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (264 aa)
	A0A1V6R966	Zn(2)-C6 fungal-type domain-containing protein. (220 aa)
	A0A1V6QUX8	Zn(2)-C6 fungal-type domain-containing protein. (381 aa)
	SEY1	Protein SEY1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (880 aa)
	A0A1V6RKJ7	Reticulon-like protein. (357 aa)
	A0A1V6RI04	Uncharacterized protein. (86 aa)
	A0A1V6RHV8	Protein YOP1. (171 aa)
	A0A1V6RCW5	Uncharacterized protein. (321 aa)
	A0A1V6RBB3	DUF2012 domain-containing protein. (272 aa)
	A0A1V6QW60	L-type lectin-like domain-containing protein. (325 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
	A0A1V6R7F7	Uncharacterized protein. (256 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V6QDV9	A0A1V6QFI0	A0A1V6QDV9	A0A1V6QFI0	MSP domain-containing protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.667
A0A1V6QDV9	A0A1V6QRR8	A0A1V6QDV9	A0A1V6QRR8	MSP domain-containing protein.	Uncharacterized protein.	0.518
A0A1V6QDV9	A0A1V6R4H7	A0A1V6QDV9	A0A1V6R4H7	MSP domain-containing protein.	Uncharacterized protein.	0.576
A0A1V6QDV9	A0A1V6RKJ7	A0A1V6QDV9	A0A1V6RKJ7	MSP domain-containing protein.	Reticulon-like protein.	0.696
A0A1V6QDV9	GET3	A0A1V6QDV9	A0A1V6QB13	MSP domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.441
A0A1V6QFI0	A0A1V6QDV9	A0A1V6QFI0	A0A1V6QDV9	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	MSP domain-containing protein.	0.667
A0A1V6QFI0	A0A1V6RBB3	A0A1V6QFI0	A0A1V6RBB3	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	DUF2012 domain-containing protein.	0.964
A0A1V6QFI0	GET1	A0A1V6QFI0	A0A1V6QTF8	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.528
A0A1V6QFI0	GET3	A0A1V6QFI0	A0A1V6QB13	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.533
A0A1V6QHX5	A0A1V6QPZ2	A0A1V6QHX5	A0A1V6QPZ2	Uncharacterized protein.	Uncharacterized protein.	0.479
A0A1V6QHX5	A0A1V6R5Y5	A0A1V6QHX5	A0A1V6R5Y5	Uncharacterized protein.	Uncharacterized protein.	0.479
A0A1V6QHX5	A0A1V6R6V3	A0A1V6QHX5	A0A1V6R6V3	Uncharacterized protein.	Uncharacterized protein.	0.479
A0A1V6QHX5	A0A1V6R966	A0A1V6QHX5	A0A1V6R966	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.479
A0A1V6QHX5	A0A1V6RCW5	A0A1V6QHX5	A0A1V6RCW5	Uncharacterized protein.	Uncharacterized protein.	0.479
A0A1V6QHX5	GET1	A0A1V6QHX5	A0A1V6QTF8	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.695
A0A1V6QHX5	GET3	A0A1V6QHX5	A0A1V6QB13	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.987
A0A1V6QPZ2	A0A1V6QHX5	A0A1V6QPZ2	A0A1V6QHX5	Uncharacterized protein.	Uncharacterized protein.	0.479
A0A1V6QPZ2	GET1	A0A1V6QPZ2	A0A1V6QTF8	Uncharacterized protein.	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.850
A0A1V6QPZ2	GET3	A0A1V6QPZ2	A0A1V6QB13	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.789
A0A1V6QRR8	A0A1V6QDV9	A0A1V6QRR8	A0A1V6QDV9	Uncharacterized protein.	MSP domain-containing protein.	0.518

page 1 of 5

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About