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A0A1V6QU42 A0A1V6QU42 A0A1V6QU88 A0A1V6QU88 MET3 MET3 A0A1V6QXM4 A0A1V6QXM4 A0A1V6QYG1 A0A1V6QYG1 A0A1V6QZX0 A0A1V6QZX0 A0A1V6R0F1 A0A1V6R0F1 A0A1V6R0G6 A0A1V6R0G6 A0A1V6R0K3 A0A1V6R0K3 A0A1V6R0K9 A0A1V6R0K9 uba4 uba4 A0A1V6R1Z3 A0A1V6R1Z3 A0A1V6R2R4 A0A1V6R2R4 A0A1V6RRS9 A0A1V6RRS9 A0A1V6RRP7 A0A1V6RRP7 A0A1V6RR37 A0A1V6RR37 A0A1V6RQM7 A0A1V6RQM7 A0A1V6RQK2 A0A1V6RQK2 A0A1V6RQ34 A0A1V6RQ34 A0A1V6RPW6 A0A1V6RPW6 A0A1V6RPM4 A0A1V6RPM4 A0A1V6R3N5 A0A1V6R3N5 NCS2 NCS2 A0A1V6R4Z6 A0A1V6R4Z6 A0A1V6R525 A0A1V6R525 A0A1V6R541 A0A1V6R541 A0A1V6R5P5 A0A1V6R5P5 A0A1V6R600 A0A1V6R600 A0A1V6R6F2 A0A1V6R6F2 A0A1V6R6S5 A0A1V6R6S5 A0A1V6R6V1 A0A1V6R6V1 A0A1V6R807 A0A1V6R807 A0A1V6R934 A0A1V6R934 A0A1V6R996 A0A1V6R996 A0A1V6R9H3 A0A1V6R9H3 A0A1V6R9R2 A0A1V6R9R2 A0A1V6R9R8 A0A1V6R9R8 A0A1V6PQ78 A0A1V6PQ78 A0A1V6PQ91 A0A1V6PQ91 A0A1V6PTE2 A0A1V6PTE2 A0A1V6PVQ7 A0A1V6PVQ7 A0A1V6PWJ8 A0A1V6PWJ8 A0A1V6PWY6 A0A1V6PWY6 A0A1V6PXU5 A0A1V6PXU5 A0A1V6PZ91 A0A1V6PZ91 A0A1V6Q044 A0A1V6Q044 A0A1V6Q127 A0A1V6Q127 A0A1V6Q5D7 A0A1V6Q5D7 A0A1V6Q5E4 A0A1V6Q5E4 A0A1V6Q8I6 A0A1V6Q8I6 A0A1V6Q9Q3 A0A1V6Q9Q3 A0A1V6QCD2 A0A1V6QCD2 A0A1V6QCE2 A0A1V6QCE2 A0A1V6QEA1 A0A1V6QEA1 A0A1V6QIT4 A0A1V6QIT4 A0A1V6QLZ1 A0A1V6QLZ1 A0A1V6QM53 A0A1V6QM53 A0A1V6QMC6 A0A1V6QMC6 A0A1V6QN15 A0A1V6QN15 A0A1V6QPR5 A0A1V6QPR5 A0A1V6QPZ6 A0A1V6QPZ6 A0A1V6QQC0 A0A1V6QQC0 A0A1V6QQK2 A0A1V6QQK2 A0A1V6QQS2 A0A1V6QQS2 A0A1V6QRB9 A0A1V6QRB9 A0A1V6RP03 A0A1V6RP03 A0A1V6RN53 A0A1V6RN53 A0A1V6RMX7 A0A1V6RMX7 A0A1V6RM40 A0A1V6RM40 A0A1V6RLU6 A0A1V6RLU6 A0A1V6RLM8 A0A1V6RLM8 A0A1V6RKY1 A0A1V6RKY1 NCS6 NCS6 A0A1V6RJF9 A0A1V6RJF9 A0A1V6RIK5 A0A1V6RIK5 A0A1V6RIF3 A0A1V6RIF3 A0A1V6RI67 A0A1V6RI67 A0A1V6REF7 A0A1V6REF7 A0A1V6RCT4 A0A1V6RCT4 A0A1V6RCF6 A0A1V6RCF6 A0A1V6RC94 A0A1V6RC94 A0A1V6RA37 A0A1V6RA37 A0A1V6RA00 A0A1V6RA00 A0A1V6QRE8 A0A1V6QRE8 A0A1V6QRT7 A0A1V6QRT7 A0A1V6QRV1 A0A1V6QRV1 A0A1V6QS11 A0A1V6QS11 A0A1V6QSA9 A0A1V6QSA9 A0A1V6QSJ0 A0A1V6QSJ0 A0A1V6QT11 A0A1V6QT11 A0A1V6QT36 A0A1V6QT36 A0A1V6QTB7 A0A1V6QTB7 A0A1V6PQ60 A0A1V6PQ60
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A1V6QU42DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1738 aa)
A0A1V6QU88tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (287 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
A0A1V6QXM4Uncharacterized protein. (177 aa)
A0A1V6QYG1ATP_transf domain-containing protein. (353 aa)
A0A1V6QZX0RPOLD domain-containing protein. (335 aa)
A0A1V6R0F1Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (723 aa)
A0A1V6R0G6Uncharacterized protein. (78 aa)
A0A1V6R0K3Uncharacterized protein. (616 aa)
A0A1V6R0K9Uncharacterized protein. (290 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (489 aa)
A0A1V6R1Z3Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1225 aa)
A0A1V6R2R4CTP_transf_like domain-containing protein. (447 aa)
A0A1V6RRS9RNA_pol_L_2 domain-containing protein. (163 aa)
A0A1V6RRP7Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (706 aa)
A0A1V6RR37HORMA domain-containing protein. (290 aa)
A0A1V6RQM7RPOLD domain-containing protein. (374 aa)
A0A1V6RQK2Uncharacterized protein. (711 aa)
A0A1V6RQ34DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2228 aa)
A0A1V6RPW6Uncharacterized protein. (322 aa)
A0A1V6RPM4Uncharacterized protein. (72 aa)
A0A1V6R3N5NTP_transferase domain-containing protein. (440 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (369 aa)
A0A1V6R4Z6DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1448 aa)
A0A1V6R525Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (384 aa)
A0A1V6R541CTP_transf_like domain-containing protein. (470 aa)
A0A1V6R5P5DNA polymerase. (1698 aa)
A0A1V6R600DNA primase; Belongs to the eukaryotic-type primase small subunit family. (505 aa)
A0A1V6R6F2RNA-dependent RNA polymerase. (1352 aa)
A0A1V6R6S5DNA polymerase. (1461 aa)
A0A1V6R6V1DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1208 aa)
A0A1V6R807BPL/LPL catalytic domain-containing protein. (445 aa)
A0A1V6R934Uncharacterized protein. (366 aa)
A0A1V6R996Uncharacterized protein. (571 aa)
A0A1V6R9H3Uncharacterized protein. (439 aa)
A0A1V6R9R2DNA polymerase. (1104 aa)
A0A1V6R9R8PAPS_reduct domain-containing protein. (328 aa)
A0A1V6PQ78Integrase catalytic domain-containing protein. (536 aa)
A0A1V6PQ91RNase H domain-containing protein. (446 aa)
A0A1V6PTE2Endo/exonuclease/phosphatase domain-containing protein. (347 aa)
A0A1V6PVQ7Uncharacterized protein. (1431 aa)
A0A1V6PWJ8Uncharacterized protein. (1178 aa)
A0A1V6PWY6Reverse transcriptase domain-containing protein. (177 aa)
A0A1V6PXU5Reverse transcriptase domain-containing protein. (82 aa)
A0A1V6PZ91Uncharacterized protein. (1559 aa)
A0A1V6Q044RT_RNaseH_2 domain-containing protein. (177 aa)
A0A1V6Q127Integrase catalytic domain-containing protein. (390 aa)
A0A1V6Q5D7Uncharacterized protein. (101 aa)
A0A1V6Q5E4Uncharacterized protein. (74 aa)
A0A1V6Q8I6Fido domain-containing protein. (260 aa)
A0A1V6Q9Q3Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (280 aa)
A0A1V6QCD2YrdC-like domain-containing protein. (241 aa)
A0A1V6QCE2Uncharacterized protein. (184 aa)
A0A1V6QEA1Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (597 aa)
A0A1V6QIT4Uncharacterized protein. (193 aa)
A0A1V6QLZ1Uncharacterized protein. (507 aa)
A0A1V6QM53Uncharacterized protein. (387 aa)
A0A1V6QMC6Uncharacterized protein. (522 aa)
A0A1V6QN15Uncharacterized protein. (234 aa)
A0A1V6QPR5NTP_transferase domain-containing protein. (364 aa)
A0A1V6QPZ6DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1671 aa)
A0A1V6QQC0BRCT domain-containing protein. (342 aa)
A0A1V6QQK2Endo/exonuclease/phosphatase domain-containing protein. (347 aa)
A0A1V6QQS2Uncharacterized protein. (503 aa)
A0A1V6QRB9Uncharacterized protein. (893 aa)
A0A1V6RP03DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1164 aa)
A0A1V6RN53DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1373 aa)
A0A1V6RMX7POLAc domain-containing protein. (1144 aa)
A0A1V6RM40Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (431 aa)
A0A1V6RLU6Uncharacterized protein. (153 aa)
A0A1V6RLM8Uncharacterized protein. (546 aa)
A0A1V6RKY1CTP_transf_like domain-containing protein. (403 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (413 aa)
A0A1V6RJF9Uncharacterized protein. (1337 aa)
A0A1V6RIK5Uncharacterized protein. (1064 aa)
A0A1V6RIF3DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (242 aa)
A0A1V6RI67RNA-dependent RNA polymerase. (1040 aa)
A0A1V6REF7BRCT domain-containing protein. (716 aa)
A0A1V6RCT4DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1249 aa)
A0A1V6RCF6mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (414 aa)
A0A1V6RC94Phosphatidate cytidylyltransferase; Belongs to the CDS family. (448 aa)
A0A1V6RA37Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (561 aa)
A0A1V6RA00RNA_pol_L_2 domain-containing protein. (138 aa)
A0A1V6QRE8Uncharacterized protein. (686 aa)
A0A1V6QRT7DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1256 aa)
A0A1V6QRV1DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (351 aa)
A0A1V6QS11UmuC domain-containing protein. (646 aa)
A0A1V6QSA9UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
A0A1V6QSJ0Uncharacterized protein. (369 aa)
A0A1V6QT11DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
A0A1V6QT36BRCT domain-containing protein. (663 aa)
A0A1V6QTB7UmuC domain-containing protein. (615 aa)
A0A1V6PQ60Integrase catalytic domain-containing protein. (538 aa)
Your Current Organism:
Penicillium solitum
NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum
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